California is currently home to 5605 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Los Angeles, San Francisco, San Diego and Sacramento. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
A Study of AMDX-2011P in Participants With Primary Open Angle Glaucoma
Recruiting
The purpose of this research study is to assess the ability of AMDX- 2011P to identify amyloid deposits in the retina of participants with Primary Open Angle Glaucoma (POAG).
Gender:
ALL
Ages:
22 years and above
Trial Updated:
07/29/2024
Locations: Global Research Management, Glendale, California
Conditions: Primary Open Angle Glaucoma
A Study of AMDX-2011P in Participants With CAA
Recruiting
The purpose of this study is to assess safety, tolerability, plasma pharmacokinetics and biologic activity of a single intravenous dose of AMDX-2011P in participants with cerebral amyloid angiopathy (CAA).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/29/2024
Locations: Global Research Management, Glendale, California
Conditions: Cerebral Amyloid Angiopathy
Addressing Taste Dysfunction With Miraculin in Head and Neck Cancer Patients Receiving Radiation Therapy
Recruiting
Patients diagnosed with head and neck cancer who receive radiation therapy with and without chemotherapy develop altered sense of taste due to treatment effect, which typically arises in the second week of radiation therapy and progresses throughout the course of treatment. While some symptoms such as pain, mucositis, and xerostomia can be managed with pain medications and saliva replacements, taste alteration has an earlier onset and is a more difficult symptom to readily address and intervene... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/29/2024
Locations: University of California, San Francisco, San Francisco, California
Conditions: Head and Neck Cancer, Taste Dysfunction
Artemis Sleep Countermeasures
Recruiting
Purpose. The purpose of this study is to test sleep and wake-promoting countermeasures to evaluate their effectiveness in helping individuals fall asleep quickly, maintain sleep during a nap, and maintain alertness during waking. Protocol Overview. The proposed study involves two laboratory visits separated by at least one week. Participants are required to complete all procedures in the companion screening and at-home protocol in order to qualify for this laboratory protocol. The at-home proto... Read More
Gender:
ALL
Ages:
Between 18 years and 60 years
Trial Updated:
07/28/2024
Locations: NASA Ames Research Center, Mountain View, California
Conditions: Fatigue
Impact of Direct Current Electrical Stimulation on Treatment of Lumbosacral Radiculopathy
Recruiting
This study will compare two methods of electrical stimulation (alternating current and direct current) as an adjunctive therapy to treating lumbosacral radiculopathy. Both types of electrical stimulation have been used in clinical practice for physical therapy, however direct current stimulation is much less common and there is less known about its impact on physical therapy outcomes. The aim of this project is to show the efficacy of a novel device, the Neubie direct current device, compared to... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/25/2024
Locations: NCEPT Physical Therapy, Escondido, California
Conditions: Radiculopathy Lumbar, Radiculopathy Sacral, Radiculopathy Multiple Sites
Pilot Evaluation of the Cynosure Potenza™ System for Treatment of Cosmetic Dermatologic Skin Conditions
Recruiting
The primary objective of this pilot study is exploratory investigation evaluating the Potenza microneedle fractional radiofrequency (RF) device and may be used in combination with the Icon intense pulsed light (IPL) device.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/25/2024
Locations: Scripps Clinic, San Diego, California
Conditions: Scars, Pigmentation, Skin Laxity, Wrinkles, Stretch Marks
Cortisol and Food Insecurity
Recruiting
This study will use a within-subjects design in a sample of individuals with a range of food insecurity recruited from the Los Angeles community (N = 400; 50% men). These participants will then, in counterbalanced order, be exposed to a gold-standard laboratory stressor and a control condition, one month apart. Moderation analyses will test whether cortisol reactivity to the stressor acts as a modulator of the relationship between high levels of food insecurity and increased hyperpalatable food... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/25/2024
Locations: University of California, Los Angeles, Los Angeles, California
Conditions: Food Insecurity
A Study of AMDX-2011P in Participants With Alzheimer's Disease
Recruiting
The purpose of this study is to assess safety, tolerability, plasma pharmacokinetics and biologic activity of a single intravenous dose of AMDX-2011P in participants with Alzheimer's Disease (AD).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/24/2024
Locations: Global Research Management, Glendale, California
Conditions: Alzheimer Disease
Defining Treatment Outcomes and Genetic Architecture in Idiopathic Toe Walking*
Recruiting
To compare and contrast the clinical, gait and parent-reported outcomes following either non-operative (casting) or operative treatment for children with idiopathic toe walking (ITW) and determine whether there are specific genes associated with ITW.
Gender:
ALL
Ages:
Between 6 years and 18 years
Trial Updated:
07/23/2024
Locations: Shriners Hospitals for Children, Sacramento, California
Conditions: Idiopathic Toe Walking
Targeting the Neurobiology of RRB in Autism Using N-acetylcysteine: Trial
Recruiting
The goal of this study is to target the neurobiology of restricted and repetitive behaviors in children with autism spectrum disorder using N-acetylcysteine (NAC), a well-tolerated nutritional supplement that has shown promise for reducing symptom severity in recent small-scale trials. The findings from this research will shed light on the mechanisms of action underlying the clinical benefits of NAC and the effects of NAC on altering restricted and repetitive behavior symptom severity in childre... Read More
Gender:
ALL
Ages:
Between 3 years and 12 years
Trial Updated:
07/23/2024
Locations: Department of Psychiatry and Behavioral Sciences, Palo Alto, California
Conditions: Autism Spectrum Disorder
Healthcare Providers as Trusted Messengers to Increase Receipt of Tax Credits Among Low-income Families
Recruiting
The purpose of this study is to pilot test the feasibility, acceptability, and preliminary efficacy of healthcare provider referrals to a tax filing app within parent-child health programs to test whether such referrals can increase receipt of tax credits among low-income parents. The study will use a single-group, pre/post test design with a sample of approximately 100 women who have a child under 6 years of age. Participants will be recruited from parental-child health programs and clinics in... Read More
Gender:
ALL
Ages:
Between 18 years and 99 years
Trial Updated:
07/23/2024
Locations: UCLA School of Nursing, Los Angeles, California
Conditions: Depression, Child Development, Stress, Physical Illness, Health Care Utilization
Targeting the Neurobiology of RRB in Autism Using N-acetylcysteine: Single-dose
Recruiting
The goal of this study is to target the neurobiology of restricted and repetitive behaviors in children with autism spectrum disorder using N-acetylcysteine (NAC), a well-tolerated nutritional supplement that has shown promise for reducing symptom severity in recent small-scale trials. The findings from this research will shed light on the mechanisms of action underlying the clinical benefits of NAC.
Gender:
ALL
Ages:
Between 3 years and 12 years
Trial Updated:
07/23/2024
Locations: Stanford University School of Medicine, Stanford, California
Conditions: Autism Spectrum Disorder