California is currently home to 5602 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Los Angeles, San Francisco, San Diego and Sacramento. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Reducing Right Ventricular Failure in Pulmonary Arterial Hypertension (RELIEVE-PAH)
Recruiting
The objectives of the RELIEVE-PAH study are to obtain first-in-human experience with the study device in patients with severe pulmonary arterial hypertension, including evidence of initial safety, device performance and possible signals of clinical effectiveness.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/06/2024
Locations: Keck Medical Center of USC, Los Angeles, California
Conditions: Pulmonary Arterial Hypertension
The Effects and Mechanisms of a High CBD Cannabis Extract (BRC-002) for the Treatment of Pain and Health in Complex Regional Pain Syndrome
Recruiting
The aim of this trial is to determine the potential effects and mechanisms of cannabinoid-induced pain relief in complex regional pain syndrome (CRPS). Multiple psychophysical approaches will be conducted in conjunction with psychological and inflammatory marker testing to determine if and how cannabinoids produce stabilized improvement in CRPS-related pain and comorbidities. The trial consisted of a pre-treatment screening period, six-week treatment period and a two-week follow-up.
Gender:
ALL
Ages:
Between 21 years and 75 years
Trial Updated:
06/05/2024
Locations: Altman Clinical and Translational Research Institute, La Jolla, California
Conditions: Complex Regional Pain Syndrome
Clinical Feasibility and Evaluation of Silicon Photon Counting CT
Recruiting
The purpose of the study is to collect data to evaluate utility of the using photon-counting CT in a clinical setting.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/05/2024
Locations: Stanford University, Palo Alto, California
Conditions: CT Photon-Counting
Physician Modified Endograft For Complex Aortic Aneurysm Repair
Recruiting
The physician modified endograft is intended for treating complex, pararenal, juxtarenal and thoracoabdominal aortic aneurysms requiring coverage of renal arteries, the superior mesenteric artery or the celiac trunk in high-risk patients who do not have an option for endovascular repair with an FDA approved endograft and have an appropriate anatomy. There will be one investigational site with a total of 40 subjects to be enrolled. Time to complete enrollment will be 24 months and the subject fol... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/04/2024
Locations: University of California San Diego, San Diego, California
Conditions: Complex Abdominal Aortic Aneurysm, Juxtarenal Aortic Aneurysm, Pararenal Aortic Aneurysm, Thoracoabdominal Aortic Aneurysm
Phenotyping Response to Spinal Cord Stimulation in Chronic Low Back Pain
Recruiting
Chronic low back pain (CLBP) is a debilitating condition and costly to treat. Long-term drug treatment often fails due to habituation, breakthrough of pain, or adverse effects of drug treatment. Opioid use to manage this pain has contributed to the opioid epidemic. Spinal cord stimulators have emerged as a promising treatment and reduces reliance on drugs. However, response to spinal cord stimulation (SCS) is unpredictable. It is difficult to predict which patients will respond positively to SCS... Read More
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
06/03/2024
Locations: University of California, Los Angeles, Los Angeles, California
Conditions: Chronic Low Back Pain
Evaluating the Feasibility of VR for Pediatric Renal Biopsies
Recruiting
The purpose of this study is to assess the use of virtual reality (VR) as an adjunct or alternative to pharmacologic sedation in pediatric patients undergoing renal biopsy.
Gender:
ALL
Ages:
Between 5 years and 17 years
Trial Updated:
06/03/2024
Locations: UCSF Benioff Children's Hospital, San Francisco, California
Conditions: Pain, Procedural, Procedural Anxiety, Sedation Complication
Eliminating Monitor Overuse Trial (EMO Trial)
Recruiting
The purpose of this study is to identify the optimal deimplementation strategies for an overused practice: continuous pulse oximetry monitoring of children hospitalized with bronchiolitis who are not receiving supplemental oxygen.
Gender:
ALL
Ages:
2 months and above
Trial Updated:
06/03/2024
Locations: University of California Davis, Davis, California
Conditions: Bronchiolitis Acute Viral
Mitral Valve Screening Survey
Recruiting
This study aims to examine the clinical profile/anatomical characteristics and natural history of patients who subsequently fail screening for transcatheter mitral valve intervention (TMVI).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/03/2024
Locations: Keck Hospital of USC, Los Angeles, California
Conditions: Mitral Valve Disease
PROMISE III: Percutaneous Deep Vein Arterialization for the Treatment of Late-Stage Chronic Limb-Threatening Ischemia
Recruiting
A prospective, single-arm, multi-center study designed to gather additional information on the LimFlow System.
Gender:
ALL
Ages:
Between 18 years and 95 years
Trial Updated:
05/31/2024
Locations: University of California, San Diego Health, La Jolla, California
Conditions: Critical Limb Ischemia, Peripheral Arterial Disease, Chronic Limb-Threatening Ischemia
Treatment of Refractory BK Infections With Related Donor BK Specific Cytotoxic T-cells (CTLs)
Recruiting
BK cytotoxic T cells (CTLs) manufactured with the Miltenyi CliniMACS Prodigy Cytokine Capture System will be safe and effective in decreasing specific viral load in children, adolescents and young adults (CAYA) with refractory BK infection post Allogeneic Hematopoietic Stem Cell Transplantation (AlloHSCT) or with primary immunodeficiencies (PID).
Gender:
ALL
Ages:
Between 1 month and 79 years
Trial Updated:
05/30/2024
Locations: University of California San Francisco, San Francisco, California
Conditions: Viral Infection, Primary Immune Deficiency Disorder
Phase II Protocol of Proton Therapy for Partial Breast Irradiation in Early Stage Breast Cancer
Recruiting
The purpose of this research study is to compare the effects (good and bad) on women and their cancer using proton radiation therapy. This study is being done to see if proton radiation therapy will prove to be beneficial for women with early stage breast cancer. A clinical study is necessary to compare the results (good or bad) of proton radiation therapy.
Gender:
FEMALE
Ages:
50 years and above
Trial Updated:
05/30/2024
Locations: California Protons Cancer Therapy Center, San Diego, California
Conditions: Breast Cancer, Breast Neoplasm, Breast Tumor, Cancer of the Breast
Registry Study for Radiation Therapy Outcomes
Recruiting
The purpose of this research study is to collect and analyze information from patients being treated with various forms of radiation therapy.
Gender:
ALL
Ages:
All
Trial Updated:
05/30/2024
Locations: California Protons Cancer Therapy Center, San Diego, California
Conditions: Neoplasms