California is currently home to 5582 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Los Angeles, San Francisco, San Diego and Sacramento. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
TLI, TBI, ATG & Hematopoietic Stem Cell Transplantation and Recipient T Regs Therapy in Living Donor Kidney Transplantation
NCT03943238
Recruiting
This study will determine whether a preparatory regimen including total lymphoid irradiation (TLI), total body irradiation (TBI), anti-thymocyte globulin (ATG) and infusion of the donor hematopoietic stem cells when given along with recipient regulatory T cells (Tregs) will allow for eventual discontinuation of anti-rejection drugs after living donor kidney transplantation.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
11/20/2023
Locations: Stanford University, Palo Alto, California
Conditions: Living Donor Kidney Transplantation
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Prevention of Postop Atrial Fibrillation Through Intraoperative Inducibility of Atrial Fibrillation and Amiodarone Treatment
NCT03868150
Recruiting
Patients undergoing first time cardiac surgery will undergo rapid atrial pacing prior to initiation of cardiopulmonary bypass to screen for AF inducibility. Patients with inducible AF will be randomized to prophylactic amiodarone treatment versus no treatment. Patients who are not inducible to AF will be treated with standard post-operative care. Patients will be monitored post-operatively to explore the value of intraoperative inducibility of AF to predict POAF and to evaluate whether the combi... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/20/2023
Locations: Stanford University, Stanford, California
Conditions: Postoperative Atrial Fibrillation
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COMParison of Algorithms for Rotational Evaluation in Atrial Fibrillation
NCT02997254
Recruiting
This is a cohort study to evaluate algorithms for mapping atrial fibrillation by mapping atrial structure and mapping electrical activity to detect focal and rotational activity.
Gender:
ALL
Ages:
Between 21 years and 90 years
Trial Updated:
11/20/2023
Locations: Stanford University, Stanford, California
Conditions: Atrial Fibrillation, Abnormal Heart Rhythms
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International Lymphatic Disease and Lymphedema Registry
NCT01336790
Recruiting
The purpose of the International Lymphatic Disease and Lymphedema Patient Registry and Biorepository is to collect health information in order to study the disease classification, natural history, and impact of Lymphatic Disease, Lymphedema and Related Disorders and its treatments and medical outcomes.
Gender:
ALL
Ages:
All
Trial Updated:
11/20/2023
Locations: Stanford University School of Medicine, Stanford, California
Conditions: Lymphedema
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Prospective Database Registry Study of Scoliosis in Children With Cerebral Palsy
NCT00680264
Recruiting
The purpose of this study is to determine the radiographic and clinical outcomes of Scoliosis surgical and non-operative treatment in patients with Cerebral Palsy.
Gender:
ALL
Ages:
Between 8 years and 21 years
Trial Updated:
11/20/2023
Locations: Rady Children's Hospital, San Diego, California
Conditions: Cerebral Palsy, Scoliosis
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The PALSUR-study: Palliative Care Versus Surgery in High-grade Glioma Patients (ENCRAM 2203)
NCT06146738
Recruiting
There is no consensus on the optimal treatment of patients with high-grade glioma, especially when patients have limited functioning performance at presentation (KPS ≤70). Therefore, there are varied practice patterns around pursuing biopsy, resection, or palliation (best supportive care). This study aims to characterize the impact of palliative care versus biopsy versus resection on survival and quality of life in these patients. Also, it will aim to determine if there is a subset of patients t... Read More
Gender:
ALL
Ages:
Between 18 years and 90 years
Trial Updated:
11/18/2023
Locations: University of California, San Francisco, San Francisco, California
Conditions: Glioblastoma, Glioblastoma Multiforme, Glioblastoma, IDH-wildtype, Glioblastoma Multiforme, Adult
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The RESBIOP-study: Resection Versus Biopsy in High-grade Glioma Patients (ENCRAM 2202)
NCT06146725
Recruiting
There are no guidelines or prospective studies defining the optimal surgical treatment for gliomas of older patients (≥70 years) or those with limited functioning performance at presentation (KPS ≤70). Therefore, the decision between resection and biopsy is varied, amongst neurosurgeons internationally and at times even within an instiutition. This study aims to compare the effects of maximal tumor resection versus tissue biopsy on survival, functional, neurological, and quality of life outcomes... Read More
Gender:
ALL
Ages:
Between 18 years and 90 years
Trial Updated:
11/18/2023
Locations: University of California, San Francisco, San Francisco, California
Conditions: Glioblastoma, Glioblastoma, IDH-wildtype, Glioblastoma Multiforme, Glioblastoma Multiforme, Adult, Glioblastoma Multiforme of Brain
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Use of Virtual and Augmented Reality Devices in Vestibular Physical Therapy for mTBI
NCT05326100
Recruiting
Rapidly evolving virtual reality (VR) and augmented reality (AR) technologies are being incorporated by many large-scale industries, and the medical field is no exception. One area that has gained significant attention in recent years is virtual rehabilitation which allows physical therapists to leverage state-of-the-art immersive virtual environments to uniquely address functional deficits in patients who are unresponsive to conventional treatment techniques. Advanced VR and AR technologies are... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
11/17/2023
Locations: Naval Health Research Center, San Diego, California
Conditions: MTBI - Mild Traumatic Brain Injury, Dysfunction of Vestibular System
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Efficacy of the Nanodropper Device on Intraocular Pressure in Patients With Glaucoma
NCT05273385
Recruiting
Glaucoma is the leading cause of irreversible blindness worldwide. Previous studies demonstrate that smaller eye drops used in the treatment of glaucoma are just as efficacious as their larger counterparts. The proposed study hopes to demonstrate the non-inferiority of using Nanodropper to lower intraoccular pressure (IOP) in glaucoma patients compared to standard of care eye drops.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/16/2023
Locations: University of California, San Francisco, San Francisco, California
Conditions: Glaucoma, Ocular Hypertension, Open Angle Glaucoma
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Still Climbin': An Intervention to Improve Coping Among Black Sexual Minority Men
NCT04587869
Recruiting
This study consists of a randomized controlled trial of a multi-session cognitive behavior therapy (CBT) group intervention that addresses coping with discrimination and medical mistrust among Black sexual minority men (SMM). Primary intervention objectives include increasing health care engagement and receipt of evidence-based preventive care, as well as better coping and reduced anticipated and internalized stigma, and medical mistrust among intervention participants.
Gender:
MALE
Ages:
18 years and above
Trial Updated:
11/16/2023
Locations: APLA Health, Los Angeles, California
Conditions: Discrimination, Social, Health Care Utilization
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Biomarkers of Depression and Treatment Response
NCT04581902
Recruiting
This study is a stratified, parallel-group, single-center study utilizing multimodal imaging techniques to identify biomarkers for Major Depressive Disorder (MDD). The study goal is to identify biomarkers for MDD and treatment response that can be implemented in clinical diagnosis and care as valid and reliable measures, through monitoring neurophysiological and electrophysiological changes across the course of transcranial magnetic stimulation (TMS) treatment.
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
11/16/2023
Locations: University of California, San Francisco, San Francisco, California
Conditions: Depressive Disorder, Major
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A Cognitive Behavioral Therapy Group Intervention to Increase HIV Testing and PrEP Use Among Latinx Sexual Minority Men
NCT04225832
Recruiting
This study consists of a randomized controlled trial (RCT) of a multi-session cognitive behavior therapy (CBT) group intervention that aims to improve HIV outcomes by increasing adaptive, effective coping responses to stigma from intersectional identities related to ethnicity, immigration status, sexual minority identity, HIV status, and PrEP use among Latinx sexual minority men (SMM).
Gender:
MALE
Ages:
18 years and above
Trial Updated:
11/16/2023
Locations: Bienestar Human Services, Inc, Los Angeles, California
Conditions: HIV
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