California is currently home to 5930 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Los Angeles, San Francisco, San Diego and Sacramento. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Discovering Novel Cancer Treatment Options Using a Comprehensive NGS-based Liquid Molecular Testing Panel in the Community Setting ("DINOSAur II")
Recruiting
To prospectively identify cancer patients whose tumors express specific molecular markers targeted by therapeutic agents from a comprehensive l i q u i d molecular test, for the purpose of selecting the most clinically appropriate treatment in a pragmatic two arm trial.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/01/2023
Locations: Adventist Health Glendale, Glendale, California
Conditions: Stage III Solid Tumors, Stage IV Solid Tumors
Discovering Novel Cancer Treatment Options Using a Comprehensive NGS-based Molecular Testing Panel in the Community Setting ("DINOSAur")
Recruiting
To prospectively identify cancer patients whose tumors express specific molecular markers targeted by therapeutic agents from a comprehensive molecular test, for the purpose of selecting the most clinically appropriate treatment in a pragmatic two arm trial.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/01/2023
Locations: Adventist Health Glendale, Glendale, California
Conditions: Stage III Solid Tumors, Stage IV Solid Tumors
A CHW Intervention to Identify and Decrease Barriers to COVID 19 Testing & Vaccination
Recruiting
The objective of this study is to compare the results of a COVID-19 specific curriculum led by LACDHS Community Health Workers (CHWs) from these same communities of safety-net patients to effectively increase COVID-19 testing and vaccination for individual patients, and to facilitate needed healthcare in a timely manner for the safety net health system, and to develop a sustained public health presence in these communities to build trust and preparedness for critical COVID-19 related future need... Read More
Gender:
All
Ages:
16 years and above
Trial Updated:
02/28/2023
Locations: Los Angeles Department of Public Health, Los Angeles, California
Conditions: Vaccine Hesitancy, COVID-19 Testing, Community Health Workers
Intralesional HPV Vaccine for Condylomata
Recruiting
This study will investigate whether injecting genital warts with small quantities of the Gardasil 9 vaccine has an effect on the warts.
Gender:
All
Ages:
18 years and above
Trial Updated:
02/28/2023
Locations: Zuckerberg San Francisco General Hospital, San Francisco, California
Conditions: Human Papilloma Virus, Warts, Warts, Genital, Condyloma, Condylomata Acuminata
A Study to Assess Safety and Efficacy of PRL3-Zumab in Patients With Solid Tumors
Recruiting
This is a multi-center, Phase 2, open-label, single dose level study of PRL3-zumab monotherapy in patients with unresectable or metastatic solid tumor.
Gender:
All
Ages:
18 years and above
Trial Updated:
02/28/2023
Locations: St. Jude Medical Center, Fullerton, California
Conditions: Solid Tumor
Microbiota Intervention to Change the Response of Parkinson's Disease
Recruiting
The clinical phenotype of Parkinson's disease (PD) is quite variable, as is the response to and side effects from medications. While many patients respond to carbidopa/levodopa early on, motor fluctuations and dyskinesias can become a problem as the condition progresses, causing significant impairment in function and quality of life. The gut microbiome is of increasing interest in PD, potentially contributing to pathophysiology and clinical phenotype. Furthermore, gut bacteria are capable of met... Read More
Gender:
All
Ages:
30 years and above
Trial Updated:
02/28/2023
Locations: University of California San Francisco, San Francisco, California
Conditions: Parkinson Disease
Liquid Biopsies in Pediatric Solid Tumors
Recruiting
This study is being done to determine if traces of tumor can be found in the blood before, during, and after patients stop treatment. We will analyze the tumor material to see if it is similar to tumor tissue and if the tumor material in blood is helpful in monitoring the disease.
Gender:
All
Ages:
6 months and above
Trial Updated:
02/27/2023
Locations: Children's Hospital Los Angeles, Los Angeles, California
Conditions: Pediatric Solid Tumor, Unspecified, Protocol Specific
Effects of ivAED™ Device on "Air-in-line" Alarms and Workflow Disruption
Recruiting
The investigators propose to test the hypothesis, that is, the effectiveness of the ivAED to eliminate air-in-line, comparing two commercially available, standard IV infusion pumps: the Braun Infusomat® Space P and the Becton-Dickenson Alaris™ model 8100 pump (the latter is currently in use as the standard IV infusion pump at Keck Hospital of USC). Testing of an IV infusion pump other the Keck Hospital of USC standard is indicated, as the independent laboratory testing of the Alaris™ 8100 pump f... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
02/27/2023
Locations: USC Keck Hospital, Los Angeles, California
Conditions: Infusion
Thymus Regeneration, Immunorestoration, and Insulin Mitigation Extension Trial
Recruiting
The TRIIM-X trial is an expanded pilot clinical study that will evaluate a personalized combination treatment regimen for thymus regeneration. The thymus is a part of the immune system that declines markedly with age, and regenerating it may prevent or reverse key aspects of immunosenescence (immune system aging) and potentially prevent or reverse key parts of the aging process more generally. The study will evaluate biomarkers for epigenetic aging and immunosenescence, as well as evaluate estab... Read More
Gender:
All
Ages:
Between 40 years and 80 years
Trial Updated:
02/27/2023
Locations: Intervene Immune, Torrance, California
Conditions: Epigenetic Aging, Immunosenescence
STS & ACC Foundation's Transcutaneous Valve Therapy (TVT) Registry Foundation's Transcutaneous Valve Therapy (TVT) Registry
Recruiting
The TVT Registry was designed to support a national surveillance system to assess the characteristics, treatments, and outcomes of patients receiving transcutaneous valve therapies.
Gender:
All
Ages:
18 years and above
Trial Updated:
02/27/2023
Locations: Hoah Memorial Hospital Presbyterian, Newport Beach, California
Conditions: Transcutaneous Valve Therapies
Atrial Fibrillation Ablation Registry
Recruiting
The Atrial Fibrillation Ablation Registry (AFib Ablation Registry™) is designed to assess the prevalence, demographics, management, and outcomes of patients undergoing percutaneous catheter ablation procedures to treat atrial fibrillation (AF).
Gender:
All
Ages:
18 years and above
Trial Updated:
02/27/2023
Locations: Hoah Memorial Hospital Presbyterian, Newport Beach, California
Conditions: Atrial Fibrillation
A Retrospective Trial to Evaluate the Micra Pacemaker
Recruiting
This is a retrospective study of our patient population implanted with the Medtronic's Leadless single-chamber ventricular pacemakers.
Gender:
All
Ages:
18 years and above
Trial Updated:
02/27/2023
Locations: Hoag Memorial Hospital Presbyterian, Newport Beach, California
Conditions: Pacemaker