California is currently home to 5575 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Los Angeles, San Francisco, San Diego and Sacramento. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Blood Flow Restriction After Meniscus Repair
Recruiting
The purpose of this study is to evaluate post-operative outcomes after meniscus surgery in participants undergoing blood flow restriction training as a rehabilitative adjunct compared to those with standard rehabilitation.
Gender:
ALL
Ages:
Between 18 years and 60 years
Trial Updated:
01/31/2023
Locations: University of California, San Francisco, San Francisco, California
Conditions: Meniscus Disorder, Meniscus, Torn Tibial, Meniscus Lesion, Meniscus Tear, Tibial, Atrophy, Muscular
A Patient-Centric Platform Trial for Precision Oncology
Recruiting
XCELSIOR is a non-interventional data registry. Information about treatments, treatment decisions and rationale, and patient outcomes including safety and effectiveness of anti-cancer therapy and associated supportive care will be collected for analysis.
Gender:
ALL
Ages:
0 years and above
Trial Updated:
01/31/2023
Locations: Cancer Commons, Los Altos, California
Conditions: Oncology
Outcomes After Weight Loss Surgery in Low-Risk Patients
Recruiting
The purpose of this research is to determine patient-reported outcomes after weight loss surgery, including changes in health, mood, quality of life, health satisfaction, and emotional health, in low-risk patients. Weight loss surgery has been well studied for patients with body mass index (BMI) 35 kg/m\^2 or more and those with weight-related medical problems who have a BMI 30 kg/m\^2 or more. However, outcomes after weight loss surgery in patients with BMI under 35 kg/m\^2 and without co-morbi... Read More
Gender:
ALL
Ages:
All
Trial Updated:
01/24/2023
Locations: Dr. Feiz and Associates, Beverly Hills, California
Conditions: Weight Loss, Bariatric Surgery
Silicon Valley Guaranteed Income Project
Recruiting
The goal of this clinical trial is to learn about how unconditional cash payments equivalent to $1,000 for 24 months (also called 'guaranteed income') might help families experiencing homelessness and/or unstable housing in Santa Clara County, California. The main questions it aims to answer are: 1. What is the impact of guaranteed income on homelessness and housing stability among families experiencing homelessness or housing instability? 2. What is the impact of guaranteed income on the heal... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/13/2023
Locations: ¡Sí Se Puede! Collective, San Jose, California
Conditions: Families Experiencing Homelessness and/or Housing Instability
Study to Assess Allogeneic Anti-CD38 A2 Dimeric Antigen Receptor T Cells in Relapsed or Refractory Multiple Myeloma
Recruiting
This is a phase 1b, open-label, dose-escalation study of STI-1492 administered by a single intravenous infusion in subjects with relapsed or refractory multiple myeloma.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/12/2023
Locations: UC Irvine, Orange, California
Conditions: Multiple Myeloma
Rett Syndrome Registry
Recruiting
The Rett Syndrome Registry is a longitudinal observational study of individuals with MECP2 mutations and a diagnosis of Rett syndrome. Designed together with the IRSF Rett Syndrome Center of Excellence Network medical directors, this study collects data on the signs and symptoms of Rett syndrome as reported by the Rett syndrome experts and by the caregivers of individuals with Rett syndrome. This study will be used to develop consensus based guidelines for the care of your loved ones with Rett s... Read More
Gender:
ALL
Ages:
Between 0 years and 99 years
Trial Updated:
01/09/2023
Locations: Children's Hospital Los Angeles, Los Angeles, California
Conditions: Rett Syndrome, Rett Syndrome, Atypical, Genetic Disease, Genetic Diseases, X-Linked, Intellectual Disability, Neurobehavioral Manifestations, Neurologic Manifestations, Neurologic Disorder, Neurodevelopmental Disorders, Nervous System Diseases
Percutaneous Electrical Nerve Field Stimulation for Adults With Irritable Bowel Syndrome
Recruiting
This is a prospective, double-blind, randomized, sham-controlled pilot study evaluating the efficacy of percutaneous electrical nerve field stimulation for the treatment of adult patients with irritable bowel syndrome (IBS).
Gender:
ALL
Ages:
Between 18 years and 60 years
Trial Updated:
01/09/2023
Locations: UCLA, Los Angeles, California
Conditions: Irritable Bowel Syndrome, Abdominal Pain, Autonomic Nervous System Imbalance
Rady Children's Institute Genomic Biorepository
Recruiting
Rady Children's Institute for Genomic Medicine (RCI) will collect biological samples (such as blood), derived genomic sequences (from DNA and RNA), and clinical features in a Biorepository as a standardized resource for future research studies. The purpose of the Genomic Institute Biorepository is to provide consented samples and data for basic and clinical research related to the genomic cause and treatment of childhood disease, and, in the future, as reference (Quality Control) data to improve... Read More
Gender:
ALL
Ages:
All
Trial Updated:
12/08/2022
Locations: Rady Pediatric Genomics & Systems Medicine Institute, San Diego, California
Conditions: Genetic Diseases
A Study of Concurrent Stereotactic Body Radiotherapy With Opdualag in Metastatic Uveal Melanoma
Recruiting
This is a phase 2 trial of concurrent stereotactic radiation therapy (SBRT) with immunotherapy with relatlimab and nivolumab for up to two years. SBRT will be given in three doses of 15Gy each to 1-5 separate metastases. Opdualag (nivolumab 480mg and relatlimab 160mg) will be given every 4 weeks for two years
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/02/2022
Locations: California Pacific Medical Center Research Institute, San Francisco, California
Conditions: Uveal Melanoma
Adoptive Cell Transfer of Autologous Tumor Infiltrating Lymphocytes and High-Dose Interleukin 2 in Select Solid Tumors
Recruiting
To determine whether special tumor fighting cells that is taken from participants' tumors and grown in the laboratory and then given back to the participant will fight the participant's cancer when their immune system is suppressed from attacking these special tumor fighting cells. This is called transfer of autologous (they came from you) tumor infiltrating lymphocytes (the cells that have been grown in the laboratory. Participants getting these cell infusions will also be treated with interleu... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/01/2022
Locations: UC San Diego Moores Cancer Center, La Jolla, California
Conditions: Metastatic Melanoma, Locally Advanced Refractory/Recurrent Melanoma, Metastatic Head and Neck Cancer, Locally Advanced Refractory/Recurrent Head and Neck Cancer
Remote Dielectric Sensing (ReDS) Assisted Diuresis in Acute Decompensated Heart Failure
Recruiting
This study evaluates the use of a wearable vest capable of non-invasively measuring lung fluid content in hospitalized patients with heart failure
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/28/2022
Locations: University of California, San Francisco, San Francisco, California
Conditions: Heart Failure; With Decompensation
StimRouter Registry Clinical Protocol
Recruiting
This Registry study will prospectively evaluate the long-term effectiveness, safety, and tolerability of the StimRouter Neuromodulation System, along with evaluating the technical performance of StimRouter, surgical outcomes, health-related quality of life, concomitant medical use, and subject's impression of improvement.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/07/2022
Locations: University of California San Diego, La Jolla, California
Conditions: Chronic Pain, Peripheral Neuropathy, Nervous System Diseases, Peripheral Nervous System Diseases, Peripheral Nervous System Problem, Peripheral Nerve Injuries, Peripheral Nervous