Colorado is currently home to 1917 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Denver, Aurora, Colorado Springs and Englewood. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
A Clinical Evaluation of the MicroSTent® PeripherAl Vascular SteNt in Subjects With Arterial Disease Below the Knee (STAND)
NCT03477604
Recruiting
Randomized multicenter clinical trial consisting of two arms; one arm treated with PTA plus the MicroStent® System and one arm treated with PTA alone. Purpose to evaluate the safety and effectiveness of using the MicroStent® Peripheral Vascular Stent System, hereafter referred to as the MicroStent® System, for the treatment of infrapopliteal lesions in subjects with peripheral arterial disease.
Gender:
All
Ages:
21 years and above
Trial Updated:
10/03/2022
Locations: Rocky Mountain Regional VA Medical Center, Aurora, Colorado
Conditions: Peripheral Arterial Disease
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Bacterial Gene Profiling to Predict Antibiotic Resistance During Cystic Fibrosis Pulmonary Exacerbations
NCT04341532
Recruiting
Pulmonary exacerbations (PEx) are key events that lead to a decline in health status among CF patients, with many never recovering to baseline health. With the advancement of new CFTR modulators and other therapies increasing the lifespan of those living with CF, it will become increasingly important to have better strategies to manage PEx in order to have better outcomes following treatment. PEx treatment decisions will need to take into consideration the increasing frequency of antimicrobial r... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
09/28/2022
Locations: National Jewish Health, Denver, Colorado
Conditions: Cystic Fibrosis
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The Role of Laryngopharyngeal Reflux in IPF
NCT03418350
Recruiting
The primary objective of this study is to show that the Supraglottic Index (SGI) is an easily-collected index that accurately identifies the presence and severity of laryngopharyngeal reflux (LPF) in idiopathic pulmonary fibrosis (IPF).
Gender:
All
Ages:
Between 40 years and 95 years
Trial Updated:
09/26/2022
Locations: National Jewish Health, Denver, Colorado
Conditions: IPF, Reflux
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Leo Study Unstable Asthma
NCT05308277
Recruiting
This is a prospective, observational study to investigate the agreement of the Leo device signal derivation with gold standard asthmatic testing in recently exacerbated asthmatic children. This study is designed for engineering validation of a wireless, wearable device (Leo) for assessing clinical control of children recovering from acute respiratory event such as asthma attack. The Leo device will monitor chest impedance, ECG and body position to calculate parameters such as respiration rate,... Read More
Gender:
All
Ages:
Between 2 years and 18 years
Trial Updated:
09/23/2022
Locations: Children's Hospital Colorado, Aurora, Colorado
Conditions: Asthma in Children
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Rare and Atypical Diabetes Network
NCT05544266
Recruiting
RADIANT is a network of 14 clinical sites and several laboratories dedicated to the study of atypical diabetes. The objective of this study is to define new forms of diabetes and the unique mechanisms underlying these forms of atypical diabetes. The specific aims are to: Identify and enroll individuals and families with undiagnosed rare and atypical forms of diabetes. Determine the etiologic basis of the metabolic disorder among individuals and families with novel forms of rare and atypical di... Read More
Gender:
All
Ages:
All
Trial Updated:
09/14/2022
Locations: University of Colorado- Denver, Aurora, Colorado
Conditions: Diabetes Mellitus, Diabetes Mellitus Progression, Glucose Intolerance, Glucose Metabolism Disorders, Metabolic Disease, Endocrine; Complications, Endocrine System Diseases
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An Open Label, Multicenter Study to Evaluate the Pharmacokinetics, Efficacy and Safety of ASCENIV™ (IGIV) in Pediatric Subjects With Primary Immunodeficiency Diseases (PIDD)
NCT05070455
Recruiting
This is a Phase IV, multicenter, open-label study of Asceniv™ administered as an intravenous infusion of Asceniv™ (IGIV) 300-800 mg/kg every 21 or 28 days in approximately 12 pediatric subjects with Primary Immunodeficiency Diseases (PIDD). The study will be conducted at 5-7 centers in the United States, with subjects receiving six (28 day cycle) or seven (21 day cycle) doses of Asceniv™ during the study.
Gender:
All
Ages:
Between 2 years and 11 years
Trial Updated:
09/13/2022
Locations: Immunoe Research Centers, Centennial, Colorado
Conditions: Primary Immune Deficiency
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Study of Relugolix in Men With Metastatic Castration-Sensitive Prostate Cancer or Non-Metastatic or Metastatic Castration-Resistant Prostate Cancer
NCT04666129
Recruiting
This study is being conducted to assess the safety and tolerability of relugolix with other agents approved for use in combination with androgen deprivation therapy (ADT) for a 12-week treatment period and an additional 40-week safety extension period in men with prostate cancer, either metastatic castration-sensitive prostate cancer (mCSPC) or non-metastatic or metastatic castration-resistant prostate cancer (nmCRPC or mCRPC).
Gender:
Male
Ages:
18 years and above
Trial Updated:
09/02/2022
Locations: Colorodo Clinical Research, Lakewood, Colorado
Conditions: Metastatic Castration-Resistant Prostate Cancer, Metastatic Castration-Sensitive Prostate Cancer, Non-Metastatic Castration-Resistant Prostate Cancer
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BTL-785F Device for Non-invasive Treatment of Wrinkles and Improvement of the Face Appearance
NCT05524805
Recruiting
This study will evaluate the clinical safety and the performance of the BTL-785F system equipped with the BTL-785-7 applicator for non-invasive treatment of facial wrinkles.
Gender:
All
Ages:
Between 21 years and 70 years
Trial Updated:
08/30/2022
Locations: AboutSkin Research, LLC, Greenwood Village, Colorado
Conditions: Wrinkle
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Sildenafil Exercise: Role of PDE5 Inhibition
NCT04039087
Recruiting
Exercise intolerance is an understudied phenomenon in people with CF. The investigators hypothesized that vascular dysfunction plays a significant role, and can be partially reversed by administration of the phosphodiesterase type 5 (PDE5) inhibitor, sildenafil.
Gender:
All
Ages:
9 years and above
Trial Updated:
08/29/2022
Locations: National Jewish Health, Denver, Colorado
Conditions: Cystic Fibrosis
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NEXAGON for the Treatment of Corneal Persistent Epithelial Defects Following Severe Ocular Chemical and/or Thermal Injuries
NCT04081103
Recruiting
This study will enroll participants with a non-infected, corneal persistent epithelial defect (PED) resulting from an ocular chemical and/or thermal ocular injury which is non-responsive or refractory to current standard of care for at least 14 days. It will assess the efficacy and safety of Nexagon® (lufepirsen) plus standard of care versus NEXAGON-vehicle (placebo) plus standard of care. The recovery of the corneal epithelium will be the primary outcome measure, defined as a cornea that re-epi... Read More
Gender:
All
Ages:
All
Trial Updated:
08/25/2022
Locations: Colorado Eye Consultants, Littleton, Colorado
Conditions: Corneal Persistent Epithelial Defect
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Navigation and Parent Peer Support to Promote Access
NCT04029220
Recruiting
Nearly one in five children in the United States has a mental health problem that interferes with daily functioning and requires intervention, and yet less than 50% of children who need mental health care receive any services. Families and especially from low-income and ethnically diverse backgrounds, experience a range of barriers to engaging in services for their children including: lack of recognition of problems and knowledge of available treatments, connecting to services, trust in provider... Read More
Gender:
All
Ages:
Between 1 year and 99 years
Trial Updated:
08/15/2022
Locations: University of Colorado School of Medicine, Aurora, Colorado
Conditions: Mental Disorder, Child, Mental Health, Family Health
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Heartfulness Meditation to Improve Resilience Among Health Care Students: A 90 Day Program
NCT04790162
Recruiting
This investigation will examine the feasibility of delivery and effect on resilience, depression and anxiety of a 90-day Heartfulness Practice delivered virtually for health care students. It is hypothesized that by providing this program on-line, students will be able to attend easily and complete the sessions. It is also hypothesized that those students who participate in the meditation program will increase resilience.
Gender:
All
Ages:
Between 20 years and 70 years
Trial Updated:
08/12/2022
Locations: University of Colorado Anschutz, Aurora, Colorado
Conditions: Mental Health Wellness 1, Stress, Psychological, Depression, Anxiety
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