Colorado is currently home to 1915 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Denver, Aurora, Colorado Springs and Englewood. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Temsirolimus Alone or Paired With Dexamethasone Delivered to the Adventitia to eNhance Clinical Efficacy After Femoropopliteal Revascularization
NCT03942601
Recruiting
This is a prospective, multi-center, pilot feasibility study to document the effects of adventitial delivery of temsirolimus or temsirolimus with dexamethasone sodium phosphate injection, USP, after revascularization of femoropopliteal lesions in symptomatic patients with moderate to severe claudication (Rutherford 2-3) or critical limb ischemia (CLI) with rest pain (Rutherford 4). Subjects will be followed for up to 60 months post index procedure.
Gender:
All
Ages:
Between 18 years and 85 years
Trial Updated:
08/31/2020
Locations: University of Colorado, Denver, Colorado
Conditions: Peripheral Arterial Disease
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Cardiovascular Innovation & Research Institute 's NEXUS Registry, the Whole is Greater Than the Parts.
NCT03428048
Recruiting
Information gathered from the patients via a disease specific questionnaire will be married to data from the National Cardiovascular Data Registry (NCDR®). Details will be continuously analyzed and used to direct quality of care at our center. The institution is categorized as a low-volume institution for percutaneous coronary intervention (PCI) for coronary artery disease treatment as well as surgical and endocardial ablation for the management of atrial fibrillation (Afib). The association bet... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/29/2020
Locations: Valley View Hospital, Glenwood Springs, Colorado
Conditions: Coronary Artery Disease, Atrial Fibrillation (AF)
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Pulmonary Hypertension Association Registry
NCT04071327
Recruiting
The PHA Registry (PHAR) is a national study about people who have pulmonary arterial hypertension (PAH) and chronic thromboembolic pulmonary hypertension (CTEPH). PHAR collects information from people with PAH and CTEPH who are cared for in participating PHA-accredited Pulmonary Hypertension Care Centers throughout the U.S. PHAR will determine how people with PAH and CTEPH are evaluated, tested, and treated, and will observe how well these participants do. The goal is to see if people with PH a... Read More
Gender:
All
Ages:
All
Trial Updated:
04/01/2020
Locations: Children's Hospital Colorado, Aurora, Colorado
Conditions: Pulmonary Arterial Hypertension, Chronic Thromboembolic Pulmonary Hypertension, Pulmonary Hypertension
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Alveolar Macrophage Programming Following Endotoxin Exposure
NCT03859050
Recruiting
The histologic hallmarks of lung inflammation include accumulation of inflammatory cells in the airspaces and interstitium, injury to alveolar epithelial and endothelial cells, loss of epithelial-capillary integrity and accumulation of edema fluid in the interstitium and airspaces. Accordingly, for alveolar repair to occur inflammation must be halted, debris and inflammatory cells removed, injured tissue cells replaced, and capillary barrier function re-established. Macrophages are key players i... Read More
Gender:
All
Ages:
Between 18 years and 50 years
Trial Updated:
08/19/2019
Locations: National Jewish Health, Denver, Colorado
Conditions: ARDS, Human
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Investigate the Development and Progression of Lung Disease in Rheumatoid Arthritis Over Time
NCT03616158
Recruiting
The purpose of this study is to investigate the link between the lungs and rheumatoid arthritis (RA). Additionally, to understand why RA patients get lung disease, how to treat, and prevent the disease.
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
06/05/2019
Locations: National Jewish Health, Denver, Colorado
Conditions: Rheumatoid Arthritis, Lung Diseases
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SOLEMN Study - Synergy Optical Coherence Tomography in Left Main PCI
NCT03474432
Recruiting
BACKGROUD: Percutaneous coronary intervention (PCI) is increasingly used to treat unprotected left main coronary artery stenosis. Protected LM PCI is considered standard of care in most centers. OCT allows for precise determination of stent placement, stent expansion and apposition. The pattern of vessel healing can be very precisely studied if immediate post-stent implantation OCT/IVUS data is compared to the 6-month post-PCI interval. While OCT cannot be optimally used for ostial lesion ima... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
01/14/2019
Locations: VA Eastern Colorado Health Care System, Denver, Colorado
Conditions: Percutaneous Coronary Intervention, Optical Coherence Tomography, In-stent Coronary Artery Restenosis
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Intensity Modulated Radiotherapy (IMRT) vs. 3D-conformal Accelerated Partial Breast Irradiation (APBI) for Early Stage Breast Cancer After Lumpectomy
NCT01185132
Recruiting
In the setting of radiotherapy as part of breast-conservation therapy for patients with early stage breast cancer, the novel planning and delivery method of intensity modulated radiotherapy is an effective and safe alternative to the commonly-used standard 3D-conformal external beam radiotherapy, spares more normal breast and lung tissue, and may lead to improved clinical outcomes.
Gender:
All
Ages:
40 years and above
Trial Updated:
06/24/2014
Locations: Rocky Mountain Cancer Centers - Aurora, Aurora, Colorado
Conditions: Breast Cancer
Register for Updates