Colorado is currently home to 1917 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Denver, Aurora, Colorado Springs and Englewood. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
An Active and Placebo-Controlled Study of Brazikumab in Participants With Moderately to Severely Active Ulcerative Colitis
NCT04718818
Recruiting
The present study D5272C00001 (Legacy # 3151-201-008) seeks to evaluate the efficacy and safety of brazikumab versus placebo in patients with moderately to severely active UC and will include assessments of clinical responses as demonstrated by improvement of symptoms and of colonic mucosal appearance as observed on endoscopy.
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
01/19/2021
Locations: Research Site, Colorado Springs, Colorado
Conditions: Ulcerative Colitis
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Study to Evaluate the Benefit of RUCONEST in Improving Neurological Symptoms in Post COVID-19 Infection
NCT04705831
Recruiting
Randomized, Double Blind, Placebo Controlled, Proof-of-Concept Study to Evaluate the Benefit of RUCONEST in Improving Neurological Symptoms in Post-SARS-CoV-2 Infection.
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
01/08/2021
Locations: IMMUNOe Research Centers, Centennial, Colorado
Conditions: Post-Viral Fatigue Syndrome, Post-Viral Disorder (Disorder), Covid19
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Evaluation of the Safety and Effectiveness of the Dexcom Glucose Monitoring (CGM) System
NCT04645641
Recruiting
Evaluation of the Safety and Effectiveness of the Dexcom Glucose Monitoring (CGM) System
Gender:
All
Ages:
2 years and above
Trial Updated:
11/25/2020
Locations: Barbara Davis Center, Aurora, Colorado
Conditions: Diabetes Mellitus
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Role of Genetics in Idiopathic Pulmonary Fibrosis (IPF)
NCT01088217
Recruiting
The purpose of this study is to investigate inherited genetic factors that play a role in the development of familial pulmonary fibrosis and to identify a group of genes that predispose individuals to develop pulmonary fibrosis. Finding the genes that cause pulmonary fibrosis is the first step at developing better methods for early diagnosis and improved treatment for pulmonary fibrosis. The overall hypothesis is that inherited genetic factors predispose individuals to develop pulmonary fibrosis... Read More
Gender:
All
Ages:
All
Trial Updated:
09/11/2020
Locations: University of Colorado Denver, Aurora, Colorado
Conditions: Idiopathic Pulmonary Fibrosis, Familial Pulmonary Fibrosis, Idiopathic Interstitial Pneumonia, Familial Interstitial Pneumonia
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Temsirolimus Alone or Paired With Dexamethasone Delivered to the Adventitia to eNhance Clinical Efficacy After Femoropopliteal Revascularization
NCT03942601
Recruiting
This is a prospective, multi-center, pilot feasibility study to document the effects of adventitial delivery of temsirolimus or temsirolimus with dexamethasone sodium phosphate injection, USP, after revascularization of femoropopliteal lesions in symptomatic patients with moderate to severe claudication (Rutherford 2-3) or critical limb ischemia (CLI) with rest pain (Rutherford 4). Subjects will be followed for up to 60 months post index procedure.
Gender:
All
Ages:
Between 18 years and 85 years
Trial Updated:
08/31/2020
Locations: University of Colorado, Denver, Colorado
Conditions: Peripheral Arterial Disease
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Cardiovascular Innovation & Research Institute 's NEXUS Registry, the Whole is Greater Than the Parts.
NCT03428048
Recruiting
Information gathered from the patients via a disease specific questionnaire will be married to data from the National Cardiovascular Data Registry (NCDR®). Details will be continuously analyzed and used to direct quality of care at our center. The institution is categorized as a low-volume institution for percutaneous coronary intervention (PCI) for coronary artery disease treatment as well as surgical and endocardial ablation for the management of atrial fibrillation (Afib). The association bet... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/29/2020
Locations: Valley View Hospital, Glenwood Springs, Colorado
Conditions: Coronary Artery Disease, Atrial Fibrillation (AF)
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Alveolar Macrophage Programming Following Endotoxin Exposure
NCT03859050
Recruiting
The histologic hallmarks of lung inflammation include accumulation of inflammatory cells in the airspaces and interstitium, injury to alveolar epithelial and endothelial cells, loss of epithelial-capillary integrity and accumulation of edema fluid in the interstitium and airspaces. Accordingly, for alveolar repair to occur inflammation must be halted, debris and inflammatory cells removed, injured tissue cells replaced, and capillary barrier function re-established. Macrophages are key players i... Read More
Gender:
All
Ages:
Between 18 years and 50 years
Trial Updated:
08/19/2019
Locations: National Jewish Health, Denver, Colorado
Conditions: ARDS, Human
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Investigate the Development and Progression of Lung Disease in Rheumatoid Arthritis Over Time
NCT03616158
Recruiting
The purpose of this study is to investigate the link between the lungs and rheumatoid arthritis (RA). Additionally, to understand why RA patients get lung disease, how to treat, and prevent the disease.
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
06/05/2019
Locations: National Jewish Health, Denver, Colorado
Conditions: Rheumatoid Arthritis, Lung Diseases
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Intensity Modulated Radiotherapy (IMRT) vs. 3D-conformal Accelerated Partial Breast Irradiation (APBI) for Early Stage Breast Cancer After Lumpectomy
NCT01185132
Recruiting
In the setting of radiotherapy as part of breast-conservation therapy for patients with early stage breast cancer, the novel planning and delivery method of intensity modulated radiotherapy is an effective and safe alternative to the commonly-used standard 3D-conformal external beam radiotherapy, spares more normal breast and lung tissue, and may lead to improved clinical outcomes.
Gender:
All
Ages:
40 years and above
Trial Updated:
06/24/2014
Locations: Rocky Mountain Cancer Centers - Aurora, Aurora, Colorado
Conditions: Breast Cancer
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