Search
Massachusetts Paid Clinical Trials
A listing of 3310 clinical trials in Massachusetts actively recruiting volunteers for paid trials and research studies in various therapeutic areas.
3265 - 3276 of 3310
Match to Clinical Trials
Access to cutting-edge treatments
Latest clinical trials
Find trials in your area
Search by Name
Filter by Condition
Filter by Location
Filter by Age
Filter by Type
Gender
Type of Study
Clinical Trial Phase
Massachusetts is currently home to 3310 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Boston, Worcester, Springfield and Burlington. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Featured Trial
Paid Clinical Studies Nationwide
Recruiting
Nationwide clinical trials offered in your area. Some trials offering up to several thousand dollars in compensation for participation.
Featured Trial
Chronic Cough Clinical Study
Recruiting
We are evaluating an investigational treatment to see if it may help people dealing with chronic cough.
Eligible participants will receive study-related medical care at no cost. You may be compensated for study-related travel and time. Health insurance is not required. If you qualify, you may receive:
Payment up to $1500, which varies by study.
Eligible participants will receive study-related medical care at no cost. You may be compensated for study-related travel and time. Health insurance is not required. If you qualify, you may receive:
Payment up to $1500, which varies by study.
Conditions:
Cough
Chronic Cough
Asthma
Allergic Asthma
Sinusitis
Featured Trial
Transcranial Magnetic Stimulation (TMS) for Obsessive Compulsive Disorder (OCD)
Recruiting
Transcranial magnetic stimulation (TMS) is an FDA-approved, non-invasive form of brain stimulation for OCD. TMS has been shown to be an effective form of treatment in individuals with OCD. By using a form of TMS termed theta-burst stimulation (TBS), we hope that this will result in a more effective treatment by producing faster symptom reduction. We are trialing a novel form of accelerated TMS, where we will deliver ten 10-minute sessions per day, for 5 days. This study will compare the efficacy of TMS for OCD at two distinct brain regions. Participants will be randomized into one of two study groups, and receive stimulation at either the DMPFC or R-OFC. Both regions have been linked to OCD by research. Patients that don't respond to their study region will have the option to receive stimulation at the other region.
Conditions:
Obsessive-Compulsive Disorder
Obsessive Compulsive Disorder
Obsessive Compulsive Disorder (OCD)
Obsessive-Compulsive Disorder (OCD)
Obsessive-compulsive Disorders and Symptoms
Featured Trial
Type 2 Diabetes Clinical Trial
Recruiting
Can changing your breakfast improve your type 2 diabetes? Join this online study from the University of Michigan.
Conditions:
Type 2 Diabetes
Diabetes Mellitus Type 2 in Obese
Diabetes Type Two
Featured Trial
High Triglyceride Clinical Research Study
Recruiting
Living with high triglycerides? See if our clinical study is right for you.
Don’t let financial stress hold you back. All clinical study-related assessments, care, and the investigational study drug are available at no cost. You could also be eligible for compensation for travel.
Don’t let financial stress hold you back. All clinical study-related assessments, care, and the investigational study drug are available at no cost. You could also be eligible for compensation for travel.
Conditions:
High Triglycerides
High Triglyceride Level
Hypertriglyceridemia
Elevated Triglycerides
Triglycerides High
FDG an Myocardial Infarction: The PIAF Trial
Recruiting
In order to define distinct and reliable arterial 18Fluorodeoxyglucose (FDG) thresholds identifying patients at risk for cardiovascular events, patients with a history of myocardial infarction will be included in this international multicenter trial. Non-enhanced whole-body FDG PET/CT will be performed in all patients and the arterial FDG uptake in the carotid arteries as well as the aorta will be quantified by calculating different uptake parameters. In addition, FDG uptake in hematopoietic tis... Read More
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
11/30/2021
Locations: Massachusetts General Hospital, Havard Medical School, Boston, Massachusetts
Conditions: History of Myocardial Infarction
LEAD IT! An App to Enable Persons With Early Stage Dementia to Lead Group Activities for Their Peers
Recruiting
The proposed Phase 2 project will involve the further development and evaluation of LEAD IT!, which is a tablet-based app designed to enable persons with dementia to lead activities for their peers (i.e., other persons with dementia). The study will examine the clinical outcomes of long-term use of the app by both Resident Leaders (RLs) and Resident Players (RPs).
The Specific Aims of the proposed Phase 2 project are to:
Develop improved Beta 1 and Beta 2 Versions of LEAD IT! with sufficient c... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
11/30/2021
Locations: Hearthstone Alzheimer Care, Winchester, Massachusetts
Conditions: Dementia, Alzheimer Disease
Meibomian Gland Probing in the Sub-Acute Phase of Patients With Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis
Recruiting
The investigators' aim is to study the effects of mechanical expression of meibomian glands on eyelid disease, ocular surface health in the subacute phase of SJS/TEN.
The primary outcome is to use meibomian gland imaging to assess the health and caliber of the meibomian glands of both lower eyelids, between the treated and non-treated eyes before and after the intervention. Monitoring of outcomes will be measured by comparing the results of meibography at the initial visit and at the 6-month fo... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
11/23/2021
Locations: Massachusetts Eye and Ear Hospital, Boston, Massachusetts
Conditions: Stevens-Johnson Syndrome, Toxic Epidermal Necrolyses, Ocular Surface Disease, Meibomitis, Meibomian Gland Dysfunction, Dry Eye
Investigation of Brain Plasticity in Autism Spectrum Disorders
Recruiting
Individuals with autism spectrum disorders (ASD) commonly experience variances in tactile behaviors, such as hypersensitivity to light touch stimuli, altered texture discrimination, and hyporesponsivity to pain. Researchers aim to investigate the somatosensory sensitivity and sensorimotor integration utilizing novel, objective behavioral assays and TMS. The main purpose is to study brain plasticity (the changes that occur in the brain through experience) in individuals with autism spectrum disor... Read More
Gender:
All
Ages:
Between 6 years and 18 years
Trial Updated:
11/04/2021
Locations: Boston Children's Hospital, Boston, Massachusetts
Conditions: Autism Spectrum Disorder
The HALT Biomarker Study
Recruiting
The purpose of the HALT Biomarkers study are to identify a panel of circulating proteins that discriminates between patients with and without Hypo-Attenuated Leaflet Thickening (HALT) and can be used to supplement the diagnosis of HALT; to characterize changes in circulating proteins after treatment of HALT with systemic anticoagulation; and to identify circulating proteins that predict the occurrence of HALT.
The study population will be adult patients undergoing transfemoral transcatheter aor... Read More
Gender:
All
Ages:
65 years and above
Trial Updated:
11/02/2021
Locations: Massachusetts General Hospital, Boston, Massachusetts
Conditions: Aortic Stenosis, Hypo-attenuated Leaflet Thickening, Bioprosthetic Valve Degeneration
Data Collection of Heart Rate and Blood Pressure
Recruiting
The purpose of the study is data collection for building and validating the algorithms for analytics of vital signs using wearable earphones (MindMics device).
Gender:
All
Ages:
Between 18 years and 90 years
Trial Updated:
10/22/2021
Locations: MindMics, Inc., Cambridge, Massachusetts
Conditions: Healthy People
Dark Adaptation as an Early Indicator of Response to Statin Therapy for Intermediate AMD
Recruiting
interventional trial for off label use of high dose atorvastatin 80 mg in intermediate AMD patients and correlate recovery response measured by dark adaptation recovery time with drusen volume reduction measured by SD-OCT
Gender:
All
Ages:
Between 50 years and 85 years
Trial Updated:
10/07/2021
Locations: Massachusetts Eye and Ear Infirmary, Boston, Massachusetts
Conditions: Age-related Macular Degeneration
A Study of MPT-0118 in Subjects With Advanced or Metastatic Refractory Solid Tumors
Recruiting
This is a Phase 1/1b open-label, dose-escalation, and cohort expansion study with BID (tablet) oral dose of MPT-0118 in subjects with advanced or metastatic refractory solid tumors.
The study will be conducted in 3 parts:
Part A: MPT-0118 dose-escalation
Part B: MPT-0118 dose-escalation in combination with pembrolizumab
Part C: Cohort expansion of MPT-0118 in combination with pembrolizumab
Gender:
All
Ages:
18 years and above
Trial Updated:
09/15/2021
Locations: Massachusetts General Hospital, Boston, Massachusetts
Conditions: Solid Tumor, Adult, Advanced Solid Tumor, Advanced Cancer, Metastatic Cancer, Refractory Cancer
Myeloma-Developing Regimens Using Genomics (MyDRUG)
Recruiting
The MyDRUG study is a type of Precision Medicine trial to treat patients with drugs targeted to affect specific genes that are mutated as part of the disease. Mutations in genes can lead to uncontrolled cell growth and cancer. Patients with a greater than 25% mutation to any of the following genes; CDKN2C, FGFR3, KRAS, NRAS, BRAF V600E, IDH2 or T(11;14) can be enrolled to one of the treatment arms. These arms have treatments specifically directed to the mutated genes. Patients that do not have a... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
09/09/2021
Locations: Massachusetts General Hospital Cancer Center, Boston, Massachusetts
Conditions: Relapsed Refractory Multiple Myeloma
Resiliency Training in Adolescents With NF1 and NF2
Recruiting
This randomized controlled trial for resiliency training in adolescents with Neurofibromatosis 1 and Neurofibromatosis 2 via secure live video to determine the efficacy two stress and symptom management programs. Both programs are 8 week group programs.
Gender:
All
Ages:
Between 12 years and 17 years
Trial Updated:
09/07/2021
Locations: Massachusetts General Hospital, Boston, Massachusetts
Conditions: Neurofibromatoses
Management of Esophagitis Following Repair of Esophageal Atresia
Recruiting
The goal of this study is to prospectively evaluate the impact of antacid therapy on esophagitis in children with repaired esophageal atresia. Recent clinical guidelines have attempted to define a systematic approach to the management of these patients with regards to minimizing and treating esophagitis (Krishnan et al 2016), however the quality of evidence supporting many of the recommendations are based on expert opinion or on limited, retrospective studies. Risk factors for esophagitis and op... Read More
Gender:
All
Ages:
Between 30 days and 17 years
Trial Updated:
09/02/2021
Locations: Boston Children's Hospital, Boston, Massachusetts
Conditions: Esophageal Atresia, Esophagitis
GARNET™ Filter (GARNET Device) IDE Used in Chronic Hemodialysis Patients With a Bloodstream Infection
Recruiting
To evaluate the feasibility of performing combined hemodialysis with the GARNET device in chronic hemodialysis patients with a blood stream infection (BSI), and measure clinical performance and safety endpoints.
Gender:
All
Ages:
Between 18 years and 90 years
Trial Updated:
09/01/2021
Locations: Beth Israel Deaconess Medical Center, Boston, Massachusetts
Conditions: Bloodstream Infection