Massachusetts is currently home to 3366 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Boston, Worcester, Springfield and Burlington. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Study on the Compensatory Mechanism of Iodine Nutrition and the Optimal Intake Level of Lactating Women
NCT04492657
Recruiting
Due to the lack of direct evidence of optimal iodine intake of Chinese children, pregnant and lactating women and infants were found during the recent revision of Chinese dietary reference intakes (DRIs) of iodine in 2013 by the applicant Pro. Zhang, and no systematical research about compensatory mechanism of iodine nutrition in lactating women was found yet. Previous study funded by United Nations International Children's Emergency Fund (UNICEF) cooperated with the international experts on iod... Read More
Gender:
All
Ages:
Between 1 day and 40 years
Trial Updated:
08/09/2020
Locations: Boston University School of Medicine; Iodine Global Network (IGN), Boston, Massachusetts
Conditions: Nutritional Requirements
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Study of Crenolanib vs Midostaurin Following Induction Chemotherapy and Consolidation Therapy in Newly Diagnosed FLT3 Mutated AML
NCT03258931
Recruiting
A phase III randomized multi-center study designed to compare the efficacy of crenolanib with that of midostaurin when administered following induction chemotherapy, consolidation chemotherapy and bone marrow transplantation in newly diagnosed AML subjects with FLT3 mutation. About 510 subjects will be randomized in a 1:1 ratio to receive either crenolanib in addition to standard first line treatment of AML (chemotherapy and if eligible, transplantation) (arm A) or midostaurin and standard treat... Read More
Gender:
All
Ages:
Between 18 years and 60 years
Trial Updated:
05/21/2020
Locations: Massachusetts General Hospital, Boston, Massachusetts
Conditions: Newly Diagnosed FLT3 Mutated AML
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Biocellular-Cellular Regenerative Treatment Scaring Alopecia and Alopecia Areata
NCT03078686
Recruiting
The primary objective of this study is to evaluate the safety and efficacy of the use of a biocellular mixture of emulsified adipose-derived tissue stromal vascular fraction (AD-tSVF) and high density platelet-rich plasma concentrate (HD- PRP). Additionally, comparison with clinical outcomes of adipose-derived cellular Stromal Vascular Fraction (AD-cSVF) + AD-tSVF + HD PRP; AD-cSVF + emulsified AD-tSVF + HD- PRP; emulsified AD-tSVF + HD PRP + AD-cSVF; AD-cSVF via intravenous infusion in treatmen... Read More
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
04/15/2020
Locations: Regeneris Medical, North Attleboro, Massachusetts
Conditions: Alopecia Areata, Scarring Alopecia
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TMS in Preclinical and Prodromal AD: Modulation of Brain Networks and Memory
NCT04294888
Recruiting
The purpose of this study is to assess the effects of non-invasive brain stimulation on memory in cognitively unimpaired older adults and in patients amnestic mild cognitive impairment (aMCI) due to Alzheimer's disease (AD). This study will use repetitive Transcranial Magnetic Stimulation (rTMS) to stimulate nodes of the Default Mode Network (DMN)- which is thought to support episodic memory and to be affected by Alzheimer's pathology. We will use functional connectivity MRI (fcMRI) to assess c... Read More
Gender:
All
Ages:
Between 60 years and 85 years
Trial Updated:
03/11/2020
Locations: Massachuetts General Hospital, Charlestown, Massachusetts
Conditions: Alzheimer Disease, Mild Cognitive Impairment, Aging
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Sleep-dependent Learning in Aging
NCT03840083
Recruiting
The specific objective of this proposed research is to understand whether deficits in sleep-dependent memory changes reflect age-related changes in sleep, memory, or both. The central hypothesis is that changes in both memory and sleep contribute to age-related changes in sleep-dependent memory processing. To this end, the investigators will investigate changes in learning following intervals of sleep (overnight and nap) and wake in young and older adults.
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
03/11/2019
Locations: University of Massachusetts, Amherst, Massachusetts
Conditions: Sleep
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REtroperitoneal SArcoma Registry: an International Prospective Initiative
NCT03838718
Recruiting
Surgery is currently the only potentially curative treatment modality for localized retroperitoneal sarcoma (RPS). Available studies regarding oncologic outcomes are mainly retrospective in nature, and RPS are recognized as a rare disease. Therefore, prospective analysis of high quality data is a top priority. Primary Objectives of this study are: to prospectively collect standardized clinical data and radiological and pathological material from primary RPS patients treated with surgery at ref... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
02/11/2019
Locations: Brigham and Women's Hospital/Dana-Farber Cancer Institute, Boston, Massachusetts
Conditions: Retroperitoneal Sarcoma
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