California is currently home to 5602 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Los Angeles, San Francisco, San Diego and Sacramento. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
TAP Blocks With Ropivacaine Continuous Infusion Catheters vs Single Dose Liposomal Bupivicaine After Kidney Transplant
Recruiting
This study is a comparison of the analgesic efficacy of transversus abdominis plane (TAP) blocks with ropivacaine bolus plus continuous ropivacaine infusion via catheters versus single shot TAP blocks with liposomal bupivacaine.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/26/2025
Locations: University of California Davis, Sacramento, California
Conditions: Transplant;Failure,Kidney, Pain, Postoperative
Effects of Fresh Watermelon Consumption on Satiety and Cardiometabolic Health
Recruiting
The goal of the proposed study is to determine the effects of fresh watermelon fruit consumption on satiety, metabolic parameters and weight management.
Gender:
ALL
Ages:
Between 18 years and 55 years
Trial Updated:
03/26/2025
Locations: Exercise and Nutritional Sciences, SDSU, San Diego, California
Conditions: Satiety
Effects of Watermelon Juice on Heart Rate Recovery and Post-exercise Muscle Soreness
Recruiting
The purpose of this study was to determine the effects of a pre-exercise, single practical dose of watermelon juice, Gatorade, sugar water or water on heart rate recovery, blood lactate levels, and 24-hour post exercise muscle soreness.
Gender:
ALL
Ages:
Between 21 years and 50 years
Trial Updated:
03/26/2025
Locations: Exercise and Nutritional Sciences, SDSU, San Diego, California
Conditions: Heart Rate Recovery
Effects of Mixed Nut Consumption on Satiety and Weight Management
Recruiting
The first goal of the proposed study is to determine acute and long-term effects of mixed nuts (almonds, hazelnuts, pecans, pistachios, walnuts, and peanuts) on metabolic parameters and weight management. While numerous studies have shown the beneficial effects of nuts on promoting negative energy balance and weight loss, mechanistic studies exploring how the inclusion of nuts in the diet promotes a negative energy balance and weight loss have not been conducted. The second goal is to determine... Read More
Gender:
ALL
Ages:
Between 18 years and 55 years
Trial Updated:
03/26/2025
Locations: School of Exercise and Nutritional Sciences, SDSU, San Diego, California
Conditions: Satiety
Bio-Repository of High Risk Cohorts for the Early Detection of Pancreas Cancer
Recruiting
Bio-repository to collect bio-specimens from patients with 1) pancreatic cysts and 2) patients at high risk, defined by family history and/or genetic mutations, for pancreatic cancer.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/26/2025
Locations: Stanford University, Stanford, California
Conditions: Pancreatic Cyst, Pancreas Disease
Microbiome Sampling During Endurance Exercise
Recruiting
The small intestine and feces of subjects undergoing endurance exercise will be sampled to examine their microbiome composition
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
03/25/2025
Locations: Stanford University, Stanford, California
Conditions: Healthy, Exercise-Induced Lactic Acidemia
Mechanistic and Clinical Outcomes of a Surgical Innovation Aimed at Minimizing GERD Associated With VSG (INNOVATE-VSG)
Recruiting
This is a two-site randomized clinical trial aiming to test whether a modified investigational bariatric surgical procedure can improve gastroesophageal reflux disease (GERD) after sleeve gastrectomy.
Gender:
ALL
Ages:
Between 18 years and 60 years
Trial Updated:
03/25/2025
Locations: University of California, Irvine, Orange, California
Conditions: Obesity, Bariatric Surgery, Sleeve Gastrectomy, Gastroesophageal Reflux Disease
Adjuvant Sacituzumab Govitecan and Nivolumab in Muscle-Invasive Urothelial Carcinoma At High-Risk Recurrence
Recruiting
This is a phase 2 study, single-arm study of adjuvant combination therapy with Sacituzumab Govitecan and Nivolumab in patients with muscle-invasive urothelial carcinoma of the bladder, ureter, or upper tract, who are high risk for cancer recurrence post curative-intent surgery based on surgical pathology.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/25/2025
Locations: Chao Family Comprehensive Cancer Center, University of California, Irvine, Orange, California
Conditions: Urothelial Carcinoma, Muscle-invasive Bladder Cancer
Ketogenic Diet and Brain Response in Anorexia Nervosa
Recruiting
This is a longitudinal study with an open design in weight recovered anorexia nervosa (wrAN) individuals. Healthy controls (HC) will also be assessed. Study participants will be carefully assessed and will have 18F-fluorodeoxyglucose (\[18F\]FDG) positron emission tomography (PET) scans for assessment of regional brain glucose uptake. The wrAN group will be compared to healthy controls. Participants in the wrAN group will then complete 14 weeks of therapeutic ketogenic diet (TKD). At the end of... Read More
Gender:
ALL
Ages:
Between 18 years and 45 years
Trial Updated:
03/25/2025
Locations: University of California San Diego, San Diego, California
Conditions: Anorexia Nervosa
Mindful Motivation for Reducing Binge Eating
Recruiting
The aim of this study is to test how acceptable and feasible a new eating intervention is in people with overweight and binge eating. This intervention combines mindful eating with motivational interviewing to target binge eating. The main questions this clinical trial aims to answer are: How well do participants accept the new intervention (acceptability)? Is the intervention practical and easy to implement (feasibility)? In this trial researchers will compare the new eating intervention (mot... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/25/2025
Locations: University of California, San Francisco, San Francisco, California
Conditions: Binge Eating, Psychological, Health Behavior, Weight, Body
Early Feasibility Study of "HyperQureTM RDN System", Laparoscopic Renal Denervation Therapy, in Patients With Resistant Hypertension
Recruiting
HQ-HTN-G01 is a prospective, multicenter, single arm, open label, early feasibility study to evaluate initial safety and device design concept of "HyperQureTM RDN System", laparoscopic renal denervation therapy, in patients with resistant hypertension on three(3) or more antihypertensive medications
Gender:
ALL
Ages:
Between 22 years and 80 years
Trial Updated:
03/25/2025
Locations: University of California Irvine, Orange, California
Conditions: Resistant Hypertension
Feasibility and Preliminary Effects of Fasting-Mimicking Diet in Asian Americans with Prediabetes
Recruiting
This is a pilot study to determine the feasibility of studying the Fasting-Mimicking Diet (FMD), a dietary approach that involves the consumption of a specifically formulated, calorie-restricted nutrition regimen with a customized macronutrient composition, ratio, and quantity over a 5- day period, on a larger scale in Asian Americans with prediabetes and to examine the preliminary effects of the diet in study participants. The main questions the study aims to answer are: 1. What are the recru... Read More
Gender:
ALL
Ages:
Between 30 years and 65 years
Trial Updated:
03/25/2025
Locations: UC Irvine, Irvine, California
Conditions: Prediabetes, Prediabetic State