California is currently home to 5605 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Los Angeles, San Francisco, San Diego and Sacramento. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Mobile Manual Standing Wheelchair for SCI
Recruiting
People with spinal cord injuries (SCI) are particularly prone to complications from excessive sitting, because many are not able to stand without support. Excessive sitting after SCI is believed to contribute to pressure injuries, pain, osteoporosis, joint stiffness, spasticity, and worsening bowel and bladder function. The VA has developed, patented, and licensed a mobile manual standing wheelchair (MMSW), and the investigators believe the key feature of being able to wheel around while in a st... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/20/2024
Locations: VA Palo Alto Health Care System, Palo Alto, CA, Palo Alto, California
Conditions: Spinal Cord Injuries and Disorders
Prehabilitation and Rehabilitation in PAD
Recruiting
To determine the effectiveness of pre and post-operative exercise therapy in patients undergoing peripheral artery stenting for peripheral arterial disease.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/19/2024
Locations: VA Palo Alto Health Care System, Palo Alto, California
Conditions: Peripheral Arterial Disease
An Investigational Scan (89Zr-DFO-GmAb PET/CT) Compared to Contrast-Enhanced CT for the Detection of Recurrent Clear Cell Renal Cell Cancer After Surgery Comparing Carbonic Anhydrase IX (CAIX) PET CT to Conventional PET CT for Post-Op Staging in Kidney Cancer
Recruiting
This phase II trial compares the safety and effectiveness of 89Zr-DFO-GmAb positron emission tomography (PET)/computed tomography (CT) compared to contrast-enhanced CT after surgery in detecting clear cell renal cell cancer that has come back (recurrent). For some patients, the risk of recurrence after surgery remains high. Conventional CT methods, such as contrast-enhanced CT, may not detect small volume or micrometastatic disease. PET/CT with radiotracers, such as 89Zr-DFO-GmAb, may improve de... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/19/2024
Locations: UCLA / Jonsson Comprehensive Cancer Center, Los Angeles, California
Conditions: Clear Cell Renal Cell Carcinoma, Sarcomatoid Renal Cell Carcinoma, Stage II Renal Cell Cancer, Stage III Renal Cell Cancer, Stage IV Renal Cell Cancer
P-CD19CD20-ALLO1 Allogeneic CAR-T Cells in the Treatment of Subjects With B Cell Malignancies
Recruiting
Phase 1 study comprised of open-label, dose escalation and expansion cohort study of P-CD19CD20-ALLO1 allogeneic T stem cell memory (Tscm) CAR-T cells in subjects with relapsed/refractory B cell malignancies
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/19/2024
Locations: University of California San Diego, La Jolla, California
Conditions: Primary Mediastinal Large B-cell Lymphoma (PMBCL), Diffuse Large B-Cell Lymphoma, Not Otherwise Specified, High-grade B-cell Lymphoma, Transformed Follicular Lymphoma (tFL), Follicular Lymphoma Grade 3B
A Diagnostic for the Early Detection of Bladder Cancer
Recruiting
To improve upon the non-invasive detection of bladder cancer by further validating a multiplex ELISA assay directed at a bladder cancer-associated diagnostic signature in voided urine samples of patients with a high risk of developing bladder cancer.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/19/2024
Locations: Long Beach VA Healthcare System, Long Beach, California
Conditions: Bladder Cancer
Wearable Devices and Biomarkers Project (Healthiomics)
Recruiting
The purpose of this study is to collect clinical data, biological specimens (e.g., blood, tumor, cerebrospinal fluid, urine sample, etc.), and digital health data from patients with tumors, cancer and/or neurological disorders in order to perform research studies that could advance patient care. By collecting these specimens, the investigators plan to create and maintain a biorepository to make data and specimens available to collaborating investigators performing research to discover predictive... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/19/2024
Locations: CureScience Institute, San Diego, California
Conditions: Brain Cancer, Neurological Disorder, Neurological Cancer
Liquid Biopsies in Pediatric Solid Tumors
Recruiting
This study is being done to determine if traces of tumor can be found in the blood before, during, and after patients stop treatment. We will analyze the tumor material to see if it is similar to tumor tissue and if the tumor material in blood is helpful in monitoring the disease.
Gender:
ALL
Ages:
6 months and above
Trial Updated:
08/19/2024
Locations: Children's Hospital Los Angeles, Los Angeles, California
Conditions: Pediatric Solid Tumor, Unspecified, Protocol Specific
CureDuchenne LinkĀ®: A Resource for Research
Recruiting
CureDuchenne link is a data hub comprised of integrated biospecimens, clinical data, and self- and/or caregiver-reported information from participants. Anyone over 4 weeks old who has been diagnosed with DMD or BMD or who is a carrier of DMD or BMD can join. Parents or legal guardians can sign up their child(ren).
Gender:
ALL
Ages:
4 weeks and above
Trial Updated:
08/19/2024
Locations: CureDuchenne, Newport Beach, California
Conditions: Duchenne Muscular Dystrophy, Becker Muscular Dystrophy
d-Limonene +Radiation +Platinum Based Chemo for Xerostomia Prevention in Locally Advanced Head and Neck Squamous Cell Carcinoma
Recruiting
This study explores the safety of d-limonene, a commercially-available dietary supplement (food) as a potential therapeutic for the severe dry mouth (xerostomia) experienced by patients with head and neck cancer as a side effect of their anti-cancer treatment.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/19/2024
Locations: Stanford University, Stanford, California
Conditions: Xerostomia
Long-Term Real-World Outcomes Study on Patients Implanted With a Neurostimulator
Recruiting
The REALITY study is a prospective, post-market, non-randomized, multi-center, single-arm, open-label study intended to collect short- and long-term safety and effectiveness data on various populations implanted with Abbott's neurostimulation systems.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/19/2024
Locations: California Orthopedics & Spine, Larkspur, California
Conditions: Chronic Pain
A Novel Multiplex ELISA Assay for Evaluating Patients With Microscopic Hematuria for Bladder Cancer
Recruiting
To improve upon the non-invasive detection of BCa by further validating a multiplex ELISA assay directed at a BCa-associated diagnostic signature in voided urine samples of patients with microscopic hematuria.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/19/2024
Locations: VA Long Beach Healthcare System, Long Beach, California
Conditions: Bladder Cancer
Visuomotor Prosthetic for Paralysis
Recruiting
The investigators objective is to run human clinical trials in which brain activity recorded through a "brain-chip" implanted in the human brain can be used to provide novel communication capabilities to severely paralyzed individuals by allowing direct brain-control of a computer interface. A prospective, longitudinal, single-arm early feasibility study will be used to examine the safety and effectiveness of using a neural communication system to control a simple computer interface and a tablet... Read More
Gender:
ALL
Ages:
Between 22 years and 65 years
Trial Updated:
08/19/2024
Locations: University of California Los Angeles, Los Angeles, California
Conditions: Quadriplegia