California is currently home to 5602 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Los Angeles, San Francisco, San Diego and Sacramento. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Aspiration in Acute Respiratory Failure Survivors 2
NCT05108896
Recruiting
The purpose of this study is to learn more about problems with swallowing that could develop in patients who are very sick and need a machine to help them breathe.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/07/2024
Locations: Stanford Univerity, Stanford, California
Conditions: Dysphagia, Aspiration
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Trial of Center-Based Vs. In-Home Pivotal Response Treatment (PRT) in Autism
NCT04899544
Recruiting
The aim of this clinical trial is to compare the efficacy of a 16-week center-based Pivotal Response Treatment (PRT-C) versus home-based Pivotal Response Treatment (PRT-H) in targeting social communication deficits in young children with autism spectrum disorder (ASD) with significant language delay. The two groups will also be compared to a control group that consists of children who are receiving treatment as usual (TAU).
Gender:
ALL
Ages:
Between 2 years and 5 years
Trial Updated:
10/07/2024
Locations: Stanford University School of Medicine, Stanford, California
Conditions: Autism, Autism Spectrum Disorder, ASD
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Stereotactic Body Radiotherapy (SBRT) for Early Treatment of Oligometastatic Adenoid Cystic Carcinoma: the SOLAR Trial
NCT04883671
Recruiting
The aim of this study is to learn whether the early initiation of a specialized and focused type of radiation called stereotactic body radiation therapy (SBRT) will impact the progression of advanced adenoid cystic carcinoma, quality of life, and overall survival. The name(s) of the study intervention involved in this study is: * Stereotactic Body Radiation Therapy (SBRT)
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/07/2024
Locations: University of California, San Francisco, San Francisco, California
Conditions: Adenoid Cystic Carcinoma, Metastatic Adenoid Cystic Carcinoma
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Post Approval Study for Treatment of Drug-resistant Adult and Pediatric Primary FSGS Using the LIPOSORBER® LA-15 System
NCT04065438
Recruiting
This multicenter, prospective, single-arm clinical study will evaluate the probable benefit and safety of the LIPOSORBER® LA-15 System for the treatment of adult patients with nephrotic syndrome associated with primary focal segmental glomerulosclerosis, when the standard treatment options, including corticosteroid and/or calcineurin inhibitors treatments, have been unsuccessful or not well tolerated, and the patient has a GFR ≥ 45 ml/min/1.73m2, or the patient has post-renal transplant recurren... Read More
Gender:
ALL
Ages:
75 years and below
Trial Updated:
10/07/2024
Locations: Loma Linda University Children's Hospital, Loma Linda, California
Conditions: Focal Segmental Glomerulosclerosis
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A Center Based Early Intervention Program for Preschoolers with Developmental Disorders
NCT04026386
Recruiting
The purpose of this study is to examine the effectiveness of a 12-week early intervention program that will include 12 weekly hours in an intensive center-based preschool environment or in the home to treat social communication deficits in children with developmental disorders. The study will include children with developmental disorders, such as Autism Spectrum Disorder, neurogenetic disorders, or intellectual disability.
Gender:
ALL
Ages:
Between 2 years and 5 years
Trial Updated:
10/07/2024
Locations: Stanford University School of Medicine, Stanford, California
Conditions: Development Disorder, Child, Developmental Disability, Development Delay, Autism Spectrum Disorder
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Dabrafenib, Trametinib, and IMRT in Treating Patients With BRAF Mutated Anaplastic Thyroid Cancer
NCT03975231
Recruiting
This trial studies how well dabrafenib, trametinib, and intensity modulated radiation therapy (IMRT) work together in treating patients with BRAF mutated anaplastic thyroid cancer. Dabrafenib and trametinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Radiation therapy uses high energy beams to kill tumor cells and shrink tumors. Giving dabrafenib, trametinib, and IMRT together may kill more tumor cells.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/07/2024
Locations: City of Hope Medical Center, Duarte, California
Conditions: BRAF NP_004324.2:p.V600E, BRAF V600K Mutation Present, Thyroid Gland Anaplastic Carcinoma
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A Center Based Study of Pivotal Response Treatment for Preschoolers with Autism
NCT03778827
Recruiting
The purpose of this study is to examine the effectiveness of pivotal response training (PRT) in an intensive center-based environment to treat social communication deficits in children with autism spectrum disorder (ASD).
Gender:
ALL
Ages:
Between 2 years and 3 years
Trial Updated:
10/07/2024
Locations: Stanford University School of Medicine, Stanford, California
Conditions: Autism Spectrum Disorder, Autism
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Neuroimaging Predictors of Improvement to Pivotal Response Treatment (PRT) in Young Children with Autism
NCT03583684
Recruiting
Autism spectrum disorder (ASD) is a very heterogeneous disorder with limited empirically validated behavioral and biological interventions. The goal of this pilot investigation is to apply a biologically-based approach to identify predictors of treatment response in children with ASD who are receiving Pivotal Response Treatment (PRT), an evidence-based behavioral intervention. Specifically, the investigators propose to identify neuroimaging biomarkers of treatment response to a PRT program (PRT-... Read More
Gender:
ALL
Ages:
Between 2 years and 4 years
Trial Updated:
10/07/2024
Locations: Stanford University, Stanford, California
Conditions: Autism Spectrum Disorder, Autism
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Local Bisphosphonate Effect on Recurrence Rate in Extremity Giant Cell Tumor of Bone
NCT03295981
Recruiting
The purpose of the clinical study is to investigate whether the local delivery of bisphosphonate as a surgical adjuvant can decrease the chance of a giant cell tumor of bone coming back to the same location. The hypothesis is that the local administration of bisphosphonate will decrease the rate of the tumor returning compared to traditional aggressive surgical removal of the tumor.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/07/2024
Locations: University of California - Los Angeles, Los Angeles, California
Conditions: Giant Cell Tumor of Bone
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Hyperpolarized 13C Pyruvate MRI Scan in Predicting Tumor Aggressiveness in Patients With Renal Tumors
NCT04258462
Recruiting
This feasibility study will evaluate how well hyperpolarized 13C pyruvate magnetic resonance imaging (MRI) scan works in predicting tumor aggressiveness in participants with renal tumors. Hyperpolarized 13C pyruvate is a non-radioactive substance with potential usage in the diagnostic imaging of tumors. Hyperpolarized 13C pyruvate MRI may help doctors determine non-invasively whether a kidney tumor is a benign tumor or cancer, and if cancer, how aggressive it is. This may help doctors and partic... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/06/2024
Locations: University of California, San Francisco, San Francisco, California
Conditions: Benign Kidney Neoplasm, Kidney Neoplasm, Renal Cell Cancer
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Cognitive Control Training for Extinction in PTSD
NCT06629064
Recruiting
The proposed study will test whether a working memory training (WMT) program improves fear extinction learning and its underlying neural circuitry in Veterans with posttraumatic stress disorder (PTSD). WMT is designed to improves the ability to maintain task-relevant information in mind. The project will further validate the relationship between working memory and fear extinction using novel computational and multivariate analyses that link to specific PTSD symptoms. If WMT can enhance fear exti... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
10/04/2024
Locations: VA San Diego Healthcare System, San Diego, CA, San Diego, California
Conditions: Post-Traumatic Stress Disorders, Stress Disorders, Traumatic, Post Traumatic Stress Disorder, PTSD, Trauma and Stressor Related Disorders
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Molecular Optimization Via Exercise (MOVE)
NCT06540287
Recruiting
This study is to investigate characteristics of muscle, blood, and urine samples from older adults (ages 65-80) who are either sedentary or athletes performing at an elite level for their age. This observational study will include bio-specimen collection, as well as physical and cognitive function testing and body composition.
Gender:
ALL
Ages:
Between 65 years and 80 years
Trial Updated:
10/04/2024
Locations: Buck Institute for Research on Aging, Novato, California
Conditions: Aging
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