California is currently home to 5616 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Los Angeles, San Francisco, San Diego and Sacramento. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Remote Patient Monitoring and Health Coaching vs. Usual Care for the Treatment of Hypertension
Recruiting
High blood pressure, also known as hypertension, affects nearly half of all Americans and increases the risk for heart disease and stroke. Only about half of people with high blood pressure have it under control. New methods to control blood pressure are needed to reduce heart attack and stroke rates. The purpose of this study is to test whether a digital program that includes personalized health coaching and remote patient monitoring with a connected blood pressure cuff, all delivered on a smar... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/26/2024
Locations: Stanford University, Redwood City, California
Conditions: Hypertension
Olorofim Aspergillus Infection Study
Recruiting
The purpose of this study is to compare treatment with olorofim versus treatment with AmBisome® followed by standard of care (SOC) in patients with IFD caused by proven IA or probable lower respiratory tract disease Aspergillus species (invasive aspergillosis, IA).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/26/2024
Locations: City of Hope National Medical Center, Duarte, California
Conditions: Invasive Aspergillosis
Treat-to-Target Serum Urate Versus Treat-to-Avoid Symptoms in Gout
Recruiting
The TRUST study is a randomized, controlled multicenter study to evaluate the management of gout by comparing two commonly used treatment strategies for gout (TTT vs TTASx) to determine the most beneficial for a patient-centered gout outcomes, as well as relevant cardiovascular-metabolic-renal endpoints.
Gender:
ALL
Ages:
Between 18 years and 90 years
Trial Updated:
09/26/2024
Locations: UCLA Health, Santa Monica, California
Conditions: Gout
Study to Assess the Safety, Tolerability, and Efficacy of IDX-1197 in Combination with XELOX or Irinotecan in Patients with Advanced Gastric Cancer
Recruiting
This is an open-label, Phase 1b/2a study to evaluate the safety and tolerability of IDX-1197 and determine the MTD and RP2D in combination with XELOX or irinotecan in patients with advanced gastric cancer.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/26/2024
Locations: USC Norris Comp. Cancer Ctr Hospital, Los Angeles, California
Conditions: Gastric Cancer
Cellular Therapy for In Utero Repair of Myelomeningocele - The CuRe Trial
Recruiting
Spina bifida, or myelomeningocele (MMC), is a birth defect that results in paralysis, excess fluid on the brain (hydrocephalus), and impaired ability to urinate and have bowel movements normally. In a previous study (the MOMS trial), surgery before birth (in-utero/fetal surgery) was shown to reduce the need for shunting for hydrocephalus. There was also some improvement in ambulation, but 58 % of the children still could not walk unassisted. This study is testing living stem cells from placenta... Read More
Gender:
ALL
Ages:
Between 19 weeks and 25 weeks
Trial Updated:
09/26/2024
Locations: UC Davis Health, Sacramento, California
Conditions: Myelomeningocele
Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ASC61in Subjects With Advanced Solid Tumors
Recruiting
This is a Phase 1, open-label, multicenter, single-arm, dose escalation study, designed to evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics, and preliminary antitumor activity of single-agent ASC61(an orally bioavailable small-molecule inhibitor of PD-L1) in subjects with advanced solid tumors for whom no standard therapy is available.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/25/2024
Locations: California Cancer Associates for Research & Excellence (cCARE), Encinitas, California
Conditions: Advanced Solid Tumors
A Study to Check the Safety of Dexlansoprazole and Learn If it Can Heal Erosive Esophagitis (EE) and Keep it Healed in Children 2 to 11 Years Old
Recruiting
Gastroesophageal reflux disease (GERD) is caused by food or acid coming up from the stomach into the esophagus, repeatedly. The esophagus is the tube that carries food and liquids from the mouth to the stomach. The body uses stomach acid to break down food, but when acid rises up into the esophagus it can hurt or damage it. People with GERD often feel food coming back up into the throat and mouth and have a burning feeling in their stomach, chest, or throat, called heartburn. Other symptoms of G... Read More
Gender:
ALL
Ages:
Between 2 years and 11 years
Trial Updated:
09/25/2024
Locations: University of California San Francisco, San Francisco, California
Conditions: Erosive Esophagitis
HNC: Human Neural Circuits Electrophysiology During Cognition
Recruiting
The purpose of this study is to understand how ketamine brings about dissociative symptoms.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/24/2024
Locations: Stanford University, Palo Alto, California
Conditions: Psychiatric Disorder
A Study of TAK-861 for the Treatment of Selected Central Hypersomnia Conditions
Recruiting
The main aim is to evaluate the safety and tolerability of TAK-861 on participants with type 1 narcolepsy, who were exposed to previously tested doses of TAK-861.
Gender:
ALL
Ages:
Between 16 years and 70 years
Trial Updated:
09/24/2024
Locations: Stanford Center for Sleep Sciences and Medicine, Redwood City, California
Conditions: Narcolepsy Type 1
A Study to Evaluate Efficacy and Safety of Light Dose in Subjects with PWB Treated with Hemoporfin PDT
Recruiting
This is a multi-center, randomized, double-blind, vehicle-controlled, and sequential group Phase 2 study. Eligible subjects aged 18 to 65 years old with PWB of face and/or neck area (except subjects for Stage One) will receive Hemoporfin PDT or vehicle PDT in 8-week cycles at fixed drug dose (5 mg/kg) and different light fluence.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
09/24/2024
Locations: UCI Health Beckman Laser Institute & Medical Clinic, Irvine, California
Conditions: Port-Wine Stain, Nevus Flammeus, Port-wine Birthmarks
Understanding Ketamine's Dissociative Effects (KD Study)
Recruiting
The purpose of this study is to understand how ketamine brings about dissociative symptoms.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/24/2024
Locations: Stanford University School of Medicine, Palo Alto, California
Conditions: Epilepsy
Non-Invasive Diagnosis of Pediatric Pulmonary Invasive Mold Infections
Recruiting
This study will establish a non-invasive diagnostic approach and evaluate clinical outcomes for children at high-risk for pulmonary invasive fungal infection (PIFI).
Gender:
ALL
Ages:
Between 120 days and 21 years
Trial Updated:
09/24/2024
Locations: Rady Children's Hospital, UCSD, La Jolla, California
Conditions: Pulmonary Invasive Aspergillosis, Pulmonary Invasive Fungal Infections