California is currently home to 5616 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Los Angeles, San Francisco, San Diego and Sacramento. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Effects of Microtox on Facial Skin Quality, Fine Wrinkles, and Texture
Recruiting
The goal of this split-face clinical trial is to test the efficacy of microtox in improving facial skin quality, fine wrinkles, and texture. Participants will: * be randomly assigned to Group A (which will receive 20 units of neuromodulator on the left side of the forehead and a placebo saline treatment on the right side) or Group B (which will receive 20 units of neuromodulator on the left side of the forehead and 20 units of a different neuromodulator brand on the right side as a comparator)... Read More
Gender:
FEMALE
Ages:
Between 18 years and 65 years
Trial Updated:
09/23/2024
Locations: K. Kay Durairaj, MD, A Medical Corp., Pasadena, California
Conditions: Skin Aging, Skin Wrinkling
Phase III Efficacy and Safety Study of Miconazole Oil for Otomycosis
Recruiting
The goal of this clinical trial is to prove the that miconazole oil works well on fungal infections of the ears, by comparing the drug with a placebo. The researcher or the participants will not know if they are getting the drug or the placebo. The researcher will show the participants how to use the drug or placebo. After 14 days of using the drug or placebo, the participants will be examined by the researcher and graded on how well the drug worked on the ear(s) fungal infection. Participants w... Read More
Gender:
ALL
Ages:
All
Trial Updated:
09/23/2024
Locations: Head and Neck Surgery Specialist, Chula Vista, California
Conditions: Otomycosis
TERPS Trial for De Novo Oligometastic Prostate Cancer
Recruiting
This research is being done to see if we can improve the outcome of prostate cancer patients who present with metastatic lesions at initial diagnosis.
Gender:
MALE
Ages:
18 years and above
Trial Updated:
09/23/2024
Locations: UC San Diego Moores Cancer Center, La Jolla, California
Conditions: Prostate Cancer, Oligometastatic Disease
Fidgeting and Attentional and Emotional Regulation in ADHD
Recruiting
This project will study how fidgeting relates to cognitive and emotional functioning in adults with attention-deficit/hyperactivity disorder (ADHD). It will determine, in a laboratory setting, whether movement and access to a "fidget device" providing sensory and motor stimulation can improve cognitive and emotional regulation (including on physiological measures) in adult ADHD. The investigators will also acquire pilot data for machine learning analyses to be used in future, large scale studies... Read More
Gender:
ALL
Ages:
Between 18 years and 30 years
Trial Updated:
09/23/2024
Locations: UC Davis MIND Institute, Sacramento, California
Conditions: ADHD
Investigation of Locus Coeruleus Function in Sustained Attention
Recruiting
The norepinephrine-producing locus coeruleus (LC) is thought to be central to a wide array of cognitive functions, like attention and goal pursuit, and has been implicated in dysfunctions including attention deficit hyperactivity disorder and schizophrenia. The goal of this proposal is to develop methods that permit measurement of activity in the human LC. Because the LC is small and located in the pons, the Investigators will use high resolution magnetic resonance imaging techniques tailored to... Read More
Gender:
ALL
Ages:
Between 18 years and 60 years
Trial Updated:
09/21/2024
Locations: University of California, Davis, Sacramento, California
Conditions: Attention - no Condition is Being Assessed - Healthy Adults
Ultrasound Neuromodulation in Essential Tremor
Recruiting
This study is being done to test whether low-intensity focused ultrasound (LIFU) (low energy sound waves) cause temporary changes in brain activity and behavior when directed at particular parts of the brain. By targeting LIFU to the parts of the brain thought to be responsible for essential tremor (ET), and measuring any associated improvement in tremor, the investigators hope to show that LIFU can be a useful tool for studying the brain circuits responsible for tremor and other brain disorders... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/20/2024
Locations: Pritzker Building, UCSF, San Francisco, California
Conditions: Essential Tremor, Neuromodulation
Geriatric Assessment Guided Interventions to Accelerate Functional Recovery After CAR-T Therapy for Patients 60 Years and Older With B-cell Non-Hodgkin Lymphoma or Multiple Myeloma, GOCART Study
Recruiting
This clinical trial compares the effectiveness of geriatric assessment (GA) guided interventions to accelerate functional recovery after chimeric antigen receptor T-cell (CAR-T) therapy compared to standard of care (SOC) in patients 60 years and older with B-cell non-Hodgkin lymphoma (NHL) or multiple myeloma (MM). A large number of patients diagnosed with cancer are over the age of 60, yet most cancer treatments are developed for younger patients. Therefore, older patients may be less likely to... Read More
Gender:
ALL
Ages:
60 years and above
Trial Updated:
09/20/2024
Locations: City of Hope Medical Center, Duarte, California
Conditions: B-Cell Non-Hodgkin Lymphoma, Multiple Myeloma
Telemedicine for Improvement of Care for Older Adults With Cancer in the Underserved Community, The GAIN-S Trial
Recruiting
This clinical trial evaluates whether geriatric assessment-driven interventions with supportive care (GAIN-S) using telemedicine can be used to identify areas of vulnerability (weakness) in older adults with cancer and guide interventions to assist the patient and the healthcare team in the underserved community. The majority of patients diagnosed with cancer are over age 65 years, yet most cancer treatments are developed and tested in a younger population. Therefore, older patients with cancer... Read More
Gender:
ALL
Ages:
65 years and above
Trial Updated:
09/20/2024
Locations: City of Hope Medical Center, Duarte, California
Conditions: Hematopoietic and Lymphoid System Neoplasm, Malignant Solid Neoplasm
Comparison of Surgery and Medicine on the Impact of Diverticulitis (COSMID) Trial
Recruiting
The COSMID (Comparison of Surgery and Medicine on the Impact of Diverticulitis) trial is a pragmatic, patient-level randomized superiority trial of elective colectomy vs. best medical management for patients with quality of life (QoL) limiting diverticular disease. A parallel observational cohort will include those who are disinclined to have their treatment choice randomized, but are willing to contribute information about their outcomes. The goal of the COSMID trial is to answer the question:... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/20/2024
Locations: Cedars-Sinai Medical Center, Los Angeles, California
Conditions: Diverticulitis
Consent for Use of Stored Patient Specimens for Future Testing
Recruiting
The purpose of this study is to obtain informed consent to use stored human biological materials (HBM) (e.g., blood and other tissues) for future studies that may include genetic testing.
Gender:
ALL
Ages:
All
Trial Updated:
09/20/2024
Locations: Univ of Southern California / LA County USC Med Ctr, Los Angeles, California
Conditions: HIV Infections
The Purpose of This Study is to Evaluate the Safety and Efficacy of D-MNA in Adult Patients With Nodular Basal Cell Carcinoma
Recruiting
The goal of the study is to learn about the safety and how effective two different strengths of D-MNA compared to a placebo (a look-alike substance that contains no drug) in the treatment of nodular basal cell skin cancer
Gender:
ALL
Ages:
Between 18 years and 85 years
Trial Updated:
09/19/2024
Locations: Site #4, Fresno, California
Conditions: Nodular Basal Cell Carcinoma
Safety and Feasibility of Umbilical Cord Wharton's Jelly Allograft Injections for Knee Osteoarthritis
Recruiting
This is a Pilot Study which is randomized, prospective, open label, dose escalation, non-controlled evaluating safety and feasibility of intra-articular Wharton's Jelly (WJ) allograft will be evaluated in patients suffering with knee osteoarthritis. The participants will be randomized to one of three dosing treatment arms that will consist of one intra-articular knee injection containing either low dose, medium dose or high dose WJ allograft tissue.
Gender:
ALL
Ages:
30 years and above
Trial Updated:
09/19/2024
Locations: R3 Anti Aging Beverly Hills, Beverly Hills, California
Conditions: Osteoarthritis, Knee