California is currently home to 5600 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Los Angeles, San Francisco, San Diego and Sacramento. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Studies of the Variable Phenotypic Presentations of Rapid-Onset Dystonia Parkinsonism and Other Movement Disorders
Recruiting
The purposes of this study are to identify persons with rapid-onset dystonia-parkinsonism (RDP) or mutations of the RDP gene, document prevalence of the disease, and map its natural history.
Gender:
ALL
Ages:
All
Trial Updated:
04/11/2024
Locations: University of California, Davis, Sacramento, California
Conditions: Dystonia, Parkinsonism
Intravenous Iron Versus Oral Iron for the Treatment of Iron Deficiency Anemia
Recruiting
This study aims to assess whether administering intravenous iron early in pregnancy, compared to standard oral iron treatment, can enhance hemoglobin levels before delivery and reduce the need for blood transfusions in patients with iron deficiency anemia. Patients diagnosed with iron deficiency anemia were randomly assigned to receive either oral or intravenous iron. Before treatment initiation, patients completed a symptom questionnaire baseline hemoglobin, and ferritin levels were measured. F... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
04/10/2024
Locations: Arrowhead Regional Medical Center, Colton, California
Conditions: Iron Deficiency Anemia of Pregnancy
Continuous Glucose Monitoring in Neonatal Hyperinsulinism
Recruiting
The investigators are studying the accuracy of Dexcom G6 continuous glucose monitors placed on babies with hyperinsulinism in the Miller Children's Hospital Neonatal Intensive Care Unit. The participants will wear the device for 10 days on their lateral thigh. Whenever blood sugars are checked by glucometer, the investigators will also record the continuous glucose monitor sugar. Additionally, if the continuous glucose monitor alarms for a low sugar or an impending low sugar, the investigators w... Read More
Gender:
ALL
Ages:
Between 24 hours and 3 months
Trial Updated:
04/10/2024
Locations: Miller Children's Hospital, Long Beach, California
Conditions: Hyperinsulinism, Hypoglycemia Neonatal
Intermittent Fasting on Body Fat and Quality of Life
Recruiting
The purpose of this investigator-initiated study to check the feasibility that intermittent fasting has on body fat loss and quality of life.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
04/10/2024
Locations: Loma Linda University, Loma Linda, California
Conditions: Healthy
Neural and Cognitive Consequences of COVID-19 Survival
Recruiting
The novel coronavirus SARS-CoV-2 infection, COVID, continues to rage throughout the world with 115,000,000 confirmed cases and over 2,500,000 deaths (as of Mar 3, 2021). This translates to millions of people surviving COVID19 infection. While the lungs are ground zero, COVID tears through organ systems from brain to blood vessels. We are now beginning to see people recover but complain of ongoing problems, including lingering cognitive problems, depression, and anxiety. We have brought together... Read More
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
04/10/2024
Locations: San Francisco Heathcare System, San Francisco, California
Conditions: COVID Long-Haul, COVID-19, COVID-19 Pandemic, Brain Fog, Memory Deficits, Concentration Ability Impaired, Fatigue
Targeting Access and Knowledge of Earned Income Tax Credit (EITC) Utilization and Policies
Recruiting
The earned income tax credit (EITC) is the largest United States poverty alleviation program, providing up to $6,600 for working families as a tax refund. Prior studies have shown the EITC's benefits for social outcomes and health. Effects are even more significant for single mothers and Black women. Despite these known benefits, 20%-33% of eligible individuals do not receive benefits, leaving $7 billion unclaimed annually. The Targeting Access and Knowledge of EITC Utilization and Policies (TAK... Read More
Gender:
FEMALE
Ages:
Between 18 years and 64 years
Trial Updated:
04/10/2024
Locations: California Special Supplemental Nutrition Program for Women, Infants, and Children (WIC), Sacramento, California
Conditions: Mental Health Issue, Food Security, Well-being
Bumetanide in Patients With Alzheimer's Disease
Recruiting
This study aims to investigate bumetanide in patients with biologically confirmed Alzheimer's disease (AD). Bumetanide is a potent diuretic administered orally and is FDA approved for the treatment of edema and hypertension. Repurposing bumetanide as a medication for AD has been proposed based on data that demonstrated its ability to "flip" the APOE genotype-dependent transcriptomic signatures in AD mouse and cell culture models. Critically, this discovery was subsequently explored in Electronic... Read More
Gender:
ALL
Ages:
Between 50 years and 85 years
Trial Updated:
04/10/2024
Locations: Stanford University, Stanford, California
Conditions: Alzheimer Disease
Long-Term Follow-Up of Patients Who Have Participated in Children's Oncology Group Studies
Recruiting
This clinical trial keeps track of and collects follow-up information from patients who are currently enrolled on or have participated in a Children's Oncology Group study. Developing a way to keep track of patients who have participated in Children's Oncology Group studies may allow doctors learn more about the long-term effects of cancer treatment and help them reduce problems related to treatment and improve patient quality of life.
Gender:
ALL
Ages:
All
Trial Updated:
04/10/2024
Locations: Kaiser Permanente Downey Medical Center, Downey, California
Conditions: Hematopoietic Cell Transplantation Recipient, Leukemia, Solid Tumor
Safety and Feasibility of Umbilical Cord Wharton's Jelly Allograft Injections for Lumbar Pain
Recruiting
This is a Pilot Study that is an open label, prospective, non-controlled study in which the safety and feasibility of Wharton's Jelly (WJ) allograft will be evaluated in 100 participants suffering with low back pain.
Gender:
ALL
Ages:
20 years and above
Trial Updated:
04/09/2024
Locations: R3 Anti Aging Beverly Hills, Beverly Hills, California
Conditions: Low Back Pain
COES: Curing Order Effects on Sealants
Recruiting
Background: Sealants are a great tool in the prevention of caries in the pediatric population. It has been shown that up to 71% of occlusal decay is preventable after a single sealant application in a fissure, and thus is the standard of care due to difficulty for pediatric patients in hygiene, diet, and overall home care until manual dexterity increases. Purpose: This prospective randomized case control study aims to look at the longevity of sealants with bonding agent cured prior to sealant p... Read More
Gender:
ALL
Ages:
Between 5 years and 14 years
Trial Updated:
04/09/2024
Locations: Herman Ostrow School of Dentistry of USC, Los Angeles, California
Conditions: Dental Sealant, Sealant Retention
Exploring the Effectiveness of Dance as an Intervention to Promote Social-Emotional Health in Children With Autism Spectrum Disorder (ASD)
Recruiting
This study will explore the effectiveness of dance as an intervention to promote social-emotional health within children with ASD.
Gender:
ALL
Ages:
Between 7 years and 11 years
Trial Updated:
04/09/2024
Locations: Loma Linda University Health, Loma Linda, California
Conditions: Autism Spectrum Disorder
Glucagon Rescue of Insulin-Induced Hypoglycemia in Adults With Type 1 Diabetes Treated With Volagidemab
Recruiting
This trial is designed to evaluate the effect of glucagon receptor antagonism by volagidemab (once weekly) on glucose recovery from hypoglycemia after treatment with glucagon in adults with type 1 diabetes. After informed consent, Screening procedures to establish subject eligibility will be performed within a period of 28 days. Approximately 24 subjects with type 1 diabetes mellitus (T1DM) on stable doses of insulin will be enrolled. After enrollment, subjects will undergo a baseline Hypoglyce... Read More
Gender:
ALL
Ages:
Between 18 years and 72 years
Trial Updated:
04/09/2024
Locations: Altman Clinical and Translational Research Institute, San Diego, California
Conditions: Type 1 Diabetes Mellitus