California is currently home to 5592 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Los Angeles, San Francisco, San Diego and Sacramento. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Optimizing Treatment of Adhesive Small Bowel Obstruction
Recruiting
Small bowel obstruction (SBO) is one of the most common causes of serious gastrointestinal disease in the US. Adhesion-related SBO (aSBO) is usually treated by the placement of a nasogastric tube (NGT) to decompress the stomach, administration of intravenous (IV) fluids and observation by a surgical team. The purpose of this feasibility study is to determine the potential for implementation of treatment protocols for aSBO and determine the feasibility of randomizing patients with aSBO to receiv... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/07/2024
Locations: University of California, Los Angeles, David Geffen School of Medicine, Los Angeles, California
Conditions: Adhesive Small Bowel Obstruction
Engaging Diverse and Underserved Communities in Cancer Awareness Training and Education
Recruiting
The University of California Davis, Comprehensive Cancer Center's (UCDCCC) Office of Community Outreach and Engagement (OCOE) serves the 19 catchment counties which approximately consists of 5 million residents. Currently, the overall catchment population cancer screening rates fall below 80%. The aim of OCOE is to increase cancer education (prevention, screening, and vaccination) and training. Through education, and encouraging participation in routine screening for early detection, this can he... Read More
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
05/07/2024
Locations: University of California, Davis Comprehensive Cancer Center, Sacramento, California
Conditions: Cancer Awareness and Prevention Education
Effect of Anti-inflammatory (ITIS) Diet in Knee Osteoarthritis
Recruiting
To study the effect of anti-inflammatory diet on clinical and biological outcomes in patients with knee osteoarthritis
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/07/2024
Locations: UCSD, La Jolla, California
Conditions: Osteoarthritis, Knee
Micro/Nanobubbles (MNBs) for Treatment of Acute and Chronic Wounds
Recruiting
The purpose of this study is to assess the safety and efficacy of Micro/nanobubbles (MNB's) for the healing of acute and chronic wounds.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/07/2024
Locations: UCI Medical Center, Orange, California
Conditions: Open Wound, Wound Heal
Dermatologic Research Evaluation and Monitoring of Sleep in Moderate-to-Severe Psoriasis
Recruiting
Getting enough sleep is important for maximizing health and well-being. When it comes to health, sleep is as vital as regular exercise and eating a balanced diet. Not getting enough sleep can lead to health problems like heart attacks, diabetes, and even cancer. Since individuals with psoriasis have these same health problems, getting better sleep may help to keep them happier and healthier. This study will look at how individuals with psoriasis sleep and if their sleep is different than indivud... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/07/2024
Locations: UCSF Psorisis Center, San Francisco, California
Conditions: Psoriasis Vulgaris
Medial-prefrontal Enhancement During Schizophrenia Systems Imaging
Recruiting
This randomized controlled trial in healthy controls (HC) and patients with schizophrenia (SZ) aims to examine 1) the underlying cognitive and neural cause of self-agency deficits in SZ; 2) the responsiveness to a novel navigated repetitive transcranial magnetic stimulation (nrTMS) target in the medial/superior prefrontal cortex (mPFC); and 3) how modulation of mPFC activity impacts the larger self-agency network to mediate changes in self-agency judgments. Our overall hypothesis is that increas... Read More
Gender:
ALL
Ages:
Between 18 years and 64 years
Trial Updated:
05/07/2024
Locations: UCSF, San Francisco, California
Conditions: Schizophrenia
Effect of Anti-inflammatory Diet in Rheumatoid Arthritis
Recruiting
In a previous exploratory study, the investigators observed an effect on disease activity outcomes of anti-inflammatory diet. The investigators also observed change in microbiome and circulating metabolites. The current study will determine whether or not the addition of anti-inflammatory diet improves the clinical outcomes in participants with rheumatoid arthritis, and the role of microbiome and circulating metabolites.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/07/2024
Locations: UCSD, La Jolla, California
Conditions: Rheumatoid Arthritis
AETOS Shoulder System
Recruiting
The goal of this study is to confirm the safety and performance of the AETOS Shoulder System for USA adoption. This is a prospective, open, adaptive, non-comparative, multi-centre investigation enrolling a maximum of 220 subjects in 2 cohorts (anatomic and reverse) at up to 15 sites. No intra-study comparator group will be included, and there will be no randomization
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/06/2024
Locations: California Pacific Orthopedics, San Francisco, California
Conditions: Shoulder Osteoarthritis, Shoulder Arthritis
Assessing Comorbidities in Epilepsy Using Eye Movement Recordings
Recruiting
This study wants to make it easier to find kids with a type of epilepsy called childhood absence epilepsy (CAE) who might have problems with ongoing seizures and thinking. Right now, doctors use tests that can be expensive and take a long time. Eysz is developing a system that looks at how kids move their eyes which might help find CAE more quickly and accurately. This study will compare Eysz with the usual tests to see if it can predict seizures and thinking problems in kids with CAE. The goal... Read More
Gender:
ALL
Ages:
Between 4 years and 12 years
Trial Updated:
05/06/2024
Locations: Children's Hospital Orange County, Orange, California
Conditions: Childhood Absence Epilepsy, Absence Seizures, Epilepsy Comorbidities
A Systems Analysis and Improvement Approach for Optimizing HIV Service Delivery in Syringe Services Programs
Recruiting
The goal of this clinical trial is to assess the effectiveness of an evidence-based, organizational-level implementation strategy, the Systems Analysis and Improvement Approach, in improving HIV service delivery (SAIA-SSP-HIV) in U.S. syringe services programs (SSPs). The main questions it aims to answer are: * Does SAIA-SSP-HIV improve delivery of HIV services (including the proportion of SSP participants receiving HIV testing) compared to implementation as usual (IAU)? * Does SAIA-SSP-HIV res... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/06/2024
Locations: University of California, San Diego, San Diego, California
Conditions: HIV Infections
In Line Aerosol Nebulization With High Flow
Recruiting
The objective of ILAN is to assess the safety, feasibility and bronchodilator efficacy of in-line bronchodilator nebulizer delivery with VMN via HFNC system in hypoxemic respiratory failure patients treated with bronchodilators and compare this method to standard-nebulization using a jet nebulizer with a facial mask. The investigators hypothesized that aerosol nebulization using HFNC/VMN represents safer and more convenient approach in hypoxemic respiratory failure patients in comparison to conv... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/06/2024
Locations: Ronald Reagan Medical Center at UCLA, Los Angeles, California
Conditions: Hypoxemic Respiratory Failure, Airway Obstruction
Clinical Outcomes of Clareon Vivity Intraocular Lens With Mini-Monovision Approach
Recruiting
Purpose is to study the clinical outcomes of Clareon Vivity and Clareon Vivity Toric intraocular lens (IOL) implants in patients who are planning to have cataract surgery in both eyes with a mini-monovision approach.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/06/2024
Locations: Palo Alto Medical Foundation, Palo Alto, California
Conditions: Aphakia, Postcataract