California is currently home to 5602 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Los Angeles, San Francisco, San Diego and Sacramento. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Peripheral Heating and Glucose Tolerance
Recruiting
Effect of peripheral heating on glucose tolerance
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
04/29/2024
Locations: San Diego State University, San Diego, California
Conditions: Glucose Tolerance
A Mobile Health Intervention to Reduce Sweet Beverage Consumption in Latino Children
Recruiting
Sugar-sweetened beverage consumption is a major contributor to childhood obesity, caries, fatty liver disease, and Type 2 diabetes. Latino children are more likely to consume sugar-sweetened beverages (SSBs) and to suffer from all of the aforementioned conditions. Reading out loud to children from birth through age 5 is critical for the promotion of language and early literacy skills. Children whose parents read aloud to them are more likely to start school with the skills required for early rea... Read More
Gender:
ALL
Ages:
Between 12 months and 59 months
Trial Updated:
04/29/2024
Locations: San Francisco General Hospital Children's Health Center, San Francisco, California
Conditions: Child Obesity, Child Development
Accelerated Intermittent Theta-Burst Stimulation (aiTBS) in Treatment-Resistant Depression of Bipolar II Disorder
Recruiting
The purpose of this study is to investigate the effectiveness of accelerated intermittent theta-burst transcranial magnetic stimulation (aiTBS) in inducing anti-depressant responses in individuals with treatment-resistant depression of bipolar II disorder. This is a double-blind, randomized, sham-controlled trial that targets a single location on the left dorsolateral prefrontal cortex (LDLPFC) using the MagPro rTMS system.
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
04/26/2024
Locations: Stanford University, Palo Alto, California
Conditions: Bipolar II Disorder, Most Recent Episode Major Depressive, Current Depressive Episode, Treatment Resistant Depression
[Lu-177]Ludotadipep in Castration-resistant Prostate Cancer(CRPC): Investigation of Drug and Application
Recruiting
Phase 1: The objective of the Phase 1 part of the clinical trial is to verify safety and tolerability (dose-limiting toxicity \[DLT\], maximum tolerated dose \[MTD\]) of a single 3.7 Giga-Becquerel (GBq) dose with the potential for one dose level de-escalation to 2.775 GBq if necessary, to determine the recommended \[177Lu\]Ludotadipep dose for use in the Phase 2a part of the trial. Phase 2a: The objective of the Phase 2a part of the trial is to evaluate safety and efficacy for repeated adminis... Read More
Gender:
MALE
Ages:
18 years and above
Trial Updated:
04/25/2024
Locations: VA Greater Los Angeles Healthcare System,Cancer Center Research, Los Angeles, California
Conditions: Metastatic Castration-resistant Prostate Cancer
Patient Decision Aid for Opioid Use Disorder
Recruiting
The aim of the study is to test the effectiveness of the Patient Decision Aid for Opioid Use Disorder (PtDA-MAT) by conducting a stepped-wedge cluster-randomized trial in CA H\&SS (stratified by rural vs. non-rural areas) for adults with OUD. Patient outcomes will be tracked by (1) personal assessments (baseline, 3 months, and 6 months): drug use, overdose, healthcare utilization, and (2) clinical and administrative records (over approximately 24 months): drug treatment status and retention, phy... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/25/2024
Locations: UCLA Integrated Substance Abuse Programs, Los Angeles, California
Conditions: Opioid Use Disorder
PREDICT Therapy Selection for JAK, T-cell, or IL-6 Inhibitor Therapies Using a Molecular Signature Response Classifier (PREDICT)
Recruiting
Prospective, multi-center-observational study conducted within the US, collecting patient samples for research and development to train, test, and validate precision medicine classifiers. These molecular signature response classifiers (MSRC) aim to predict response status to JAK, T-cell, and IL-6 inhibitor therapies in patients with rheumatoid arthritis (RA).
Gender:
ALL
Ages:
Between 18 years and 100 years
Trial Updated:
04/24/2024
Locations: Medvin Clinical Research//Amicus Arthritis, Whittier, California
Conditions: Rheumatoid Arthritis
Wound Irrigation Comparative Effectiveness Study
Recruiting
The primary objective of this study is to compare the presence of C acnes in bacteriologic cultures taken from participant samples of subcutaneous and deep tissue prior to deep surgical irrigation using either Normal Saline Irrigation (Group 1) or Irrisept Irrigation (Group 2). Secondary objectives are evaluation of patient reported outcome measures and range of motion in relation to C acnes presence among subjects in the two groups.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/24/2024
Locations: Hoag Orthopedics, Orange, California
Conditions: Cutibacterium Acnes Contamination
Phase 2 Trial of HY209gel in Atopic Dermatitis Patients
Recruiting
This is a randomized, double-blind, placebo-controlled, multi-center, phase 2 study in patients with mild to moderate Atopic Dermatitis(AD), which consists of 2 parts.
Gender:
ALL
Ages:
Between 18 years and 100 years
Trial Updated:
04/24/2024
Locations: RAOOF MD Dermatology, Encino, California
Conditions: Atopic Dermatitis, Atopic Dermatitis Eczema, Atopic Dermatitis of Scalp
A Study of SNP-ACTH (1-39) Gel in Patients With Primary Membranous Nephropathy
Recruiting
The goal of the Phase 3a part of this clinical trial is to determine the optimal dose that will be used in the Phase 3b part of this clinical trial. The goal of the Phase 3b part is to assess the efficacy of SNP-ACTH (1-39) Gel relative to rituximab in patients with primary membranous nephropathy (PMN) at month 24.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/24/2024
Locations: Academic Medical Research Institute, Los Angeles, California
Conditions: Primary Membranous Nephropathy
Study of Dextromethorphan in OCD and Related Disorders
Recruiting
The purpose of the study is to assess the tolerability and efficacy of dextromethorphan in combination with fluoxetine for symptom relief in OCD and related disorders.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
04/24/2024
Locations: Stanford University, Stanford, California
Conditions: Obsessive-Compulsive Disorder, Illness Anxiety Disorder, Body Dysmorphic Disorders, Somatic Symptom Disorder
The Effect of Adipose-Derived Stem Cells for Knee Osteoarthritis
Recruiting
The purpose of this study is to compare the clinical and functional outcomes of patients with mild to moderate arthroscopically confirmed osteoarthritis between the following two groups: 1. Partial fat pad harvest with Adipose-Derived Stem Cell (ADSC) transplantation with standard arthroscopic treatment consisting of: partial meniscectomy, cartilage stabilization, loose body removal and selective synovectomy. 2. Standard arthroscopic treatment (above) without cell transplant.
Gender:
ALL
Ages:
Between 35 years and 70 years
Trial Updated:
04/24/2024
Locations: Kerlan Jobe Orthopedic Institute, Santa Monica, California
Conditions: Knee Osteoarthritis
Microfracture Versus Adipose Derived Stem Cells for the Treatment of Articular Cartilage Defects
Recruiting
The purpose of this study is to compare two biologic methods for the treatment of articular cartilage defects in the knee. The first method, microfracture, is the standard of care and is routinely used to recruit cells from the subchondral bone marrow to the site of cartilage loss. The second method is the application of adipose-derived stem cells (ADSCs) to the defect site. In theory, ADSCs on a collagen scaffold should enable the delivery of more specific progenitor cells to the site of injury... Read More
Gender:
ALL
Ages:
Between 18 years and 50 years
Trial Updated:
04/24/2024
Locations: Stanford Medical Outpatient Center, Redwood City, California
Conditions: Degenerative Lesion of Articular Cartilage of Knee