California is currently home to 5930 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Los Angeles, San Francisco, San Diego and Sacramento. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
A Multicenter National Prospective Study of Pregnancy and Neonatal Outcomes in Women With Inflammatory Bowel Disease
Recruiting
A Multicenter National Prospective Study of Pregnancy and Neonatal Outcomes in Women with Inflammatory Bowel Disease study is being conducted at the University of California San Francisco and 30 other sites around the United States who are part of the CCFA Clinical Alliance. The aim of this study is to determine the effect of medication use and disease activity on the outcome of pregnancy among women with IBD up to 18 years from birth.
Gender:
Female
Ages:
Between 18 years and 45 years
Trial Updated:
07/06/2023
Locations: Please Contact Jessica Lim For Further Information Regarding Other Sites' Locations, San Francisco, California
Conditions: Inflammatory Bowel Disease
Pilot Study: Stress Reduction in Caregivers of Children With ASD Using ACT
Recruiting
Parents/Caregivers of children with autism need psychological flexibility and self-efficacy for the ACT program to be effective. This study will compare intervention differences between groups. Repeated measures will be given three times (pre-intervention, post-intervention, and follow-up) to an ACT intervention group and a support group (control). The purpose of the present study is to compare the effects of a brief ACT-based workshop for parents of children with autism with a concurrent paren... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
07/05/2023
Locations: Fielding Graduate University, Santa Barbara, California
Conditions: Caregiver Stress
Brain Response to an Intervention Using Guided, At-Home Technology for the Mind
Recruiting
The objective of this study is to assess the effectiveness of two digital programs for providing mental stimulation, improving cognition, and inducing changes in brain structure and function.
Gender:
All
Ages:
Between 25 years and 80 years
Trial Updated:
07/05/2023
Locations: Lumos Labs, Inc., San Francisco, California
Conditions: Cognition, Brain Health, Brain Structure, Brain Function
Imaging Study of [89Zr]DFO-YS5 for Detecting CD46 Positive Malignancy in Multiple Myeloma
Recruiting
This phase I trial tests the safety of [89Zr]DFO-YS5 positron emission tomography (PET) imaging and how well it works to detect CD46 positive cancer cells in patients with multiple myeloma. [89Zr]DFO-YS5 is an imaging agent called a radiopharmaceutical tracer. A radiopharmaceutical tracer uses a small amount of radioactive material that is injected into a vein to help image different areas of the body. [89Zr]DFO-YS5 targets a specialized protein called CD46, which is in certain multiple myeloma... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
07/05/2023
Locations: University of California, San Francisco, San Francisco, California
Conditions: Multiple Myeloma, Plasma Cell Myeloma
A Study to Evaluate Safety and Efficacy of AMB-05X Injections in Subjects With TGCT
Recruiting
AMB-051-07 is an Open-Label, Adaptive, Dose-Ranging Study with Long-Term Extension which will enroll approximately 48 adult subjects with TGCT for IA doses over a 24-week dosing period (Part 1) with a Part 2 OLE of 6 treatment and/or observational cycles of 12 weeks each followed by 12 weeks of follow-up.
Gender:
All
Ages:
18 years and above
Trial Updated:
07/05/2023
Locations: AmMax Bio, Clinical Site, Sacramento, California
Conditions: Pigmented Villonodular Synovitis, TGCT, Tenosynovial Giant Cell Tumor
The Use of Image-Based Computer Gradings in the Analysis of Acne, Rosacea, Melasma, and Seborrheic Dermatitis
Recruiting
The study is conducted to determine if image-based computer grading can of acne, melasma, rosacea and seborrheic dermatitis correlate well to expert based clinical severity grading.
Gender:
All
Ages:
18 years and above
Trial Updated:
07/04/2023
Locations: Integrative Skin and Research, Sacramento, California
Conditions: Acne, Melasma, Rosacea, Seborrheic Dermatitis
The Radiation Oncology-Biology Integration Network (ROBIN) Molecular Characterization Trial (MCT) of Standard Short Course Radiotherapy for Rectal Cancer
Recruiting
This trial (molecular characterization trial) focuses on rectal cancer, a common cancer that is treated with radiotherapy (RT) as standard of care and represents a setting in which to study the effects of RT on the immune system.
Gender:
All
Ages:
Between 18 years and 90 years
Trial Updated:
07/03/2023
Locations: Cedars-Sinai Medical Center, Los Angeles, California
Conditions: Rectal Cancer
Monitoring Pregnancy and Infant Outcomes Following Tralokinumab Exposure During Pregnancy in the US and Canada - PROTECT
Recruiting
The goal of this observational study is to learn about exposure to tralokinumab during pregnancy, as well as atopic dermatitis (AD) during pregnancy. The main question the study aims to answer is whether pregnant people who have been exposed to tralokinumab during pregnancy experience any differences in pregnancy and infant outcomes compared to women with atopic dermatitis who have not been exposed to tralokinumab during pregnancy. Participants are not required to take tralokinumab during the s... Read More
Gender:
Female
Ages:
All
Trial Updated:
07/03/2023
Locations: University of California San Diego (UCSD), La Jolla, California
Conditions: Atopic Dermatitis, Eczema
Ensuring Precision-Medicine Delivery for Veterans With Lung Cancer
Recruiting
The goal of this study is to learn if using a lay VA volunteer, who will assist patients with education regarding precision medicine, can improve care quality and outcomes for Veteran patients with lung cancer.
Gender:
All
Ages:
18 years and above
Trial Updated:
07/03/2023
Locations: VA Palo Alto, Palo Alto, California
Conditions: Lung Cancer
Determining the Role of Social Reward Learning in Social Anhedonia
Recruiting
This is a clinical trial study that aims to evaluate the specificity of the relationship between reduced sensitivity to social reward and social anhedonia at both behavioral and neural levels. Individuals who recently experienced their first-episode psychosis will be recruited. Participants will be randomized 1:1 to motivational interviewing or a time- and format-matched control probe. At pre- and post-probe, participants will perform two social reward learning tasks in the scanner. With this de... Read More
Gender:
All
Ages:
Between 18 years and 35 years
Trial Updated:
07/03/2023
Locations: University of California Los Angeles, Los Angeles, California
Conditions: Psychosis
Effect of Ultra-low Dose Naloxone on Remifentanil-Induced Hyperalgesia
Recruiting
The purpose of this study is to evaluate whether using ultra-low dose naloxone, an opioid antagonist, has the potential to block remifentanil-induced hyperalgesia and tolerance following surgery. There are 3 study groups: (1) low dose remifentanil (LO, 0.1 micrograms/kg/mL), (2) high dose remifentanil (0.4 mg) combined with placebo (HI, 0.4 micrograms/kg/mL), or (3) high dose remifentanil (0.4 mg) combined with ultra-low dose naloxone (HN, 0.004 micrograms/kg/mL naloxone). The hypothesis of th... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
07/03/2023
Locations: UC Irvine Medical Center, Orange, California
Conditions: Hyperalgesia
Daratumumab, Pomalidomide, and Dexamethasone (DPd) in Relapsed/Refractory Light Chain Amyloidosis Patients Previously Exposed to Daratumumab
Recruiting
This study will test the hypothesis that in patients with previous daratumumab exposure, combination therapy of daratumumab, pomalidomide, and dexamethasone (DPd) will yield higher complete remission (CR) rates in relapsed/refractory amyloidosis than historical pomalidomide/dexamethasone treatment.
Gender:
All
Ages:
18 years and above
Trial Updated:
07/02/2023
Locations: Stanford University, Palo Alto, California
Conditions: Amyloid, AL Amyloidosis, Refractory AL Amyloidosis