California is currently home to 5930 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Los Angeles, San Francisco, San Diego and Sacramento. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
IUD Placement Without Sounding
Recruiting
The purpose of this study is to determine the feasibility of a uterine sound sparing technique for levonorgestrel 52 mg intrauterine device (IUD) placement. This study will be conducted in three phases. In phase one, the IUD will be placed in standard fashion with a uterine sound to obtain baseline data. Phase two and three are interventional phases that will investigate IUD placement without the use of a uterine sound. In phase two, the IUD will be placed without the use of a uterine sound, but... Read More
Gender:
Female
Ages:
18 years and above
Trial Updated:
06/13/2023
Locations: University of California Davis, Sacramento, California
Conditions: IUD, IUD Insertion Complication, IUD; Complications
Newborn Abdominal Massage to Prevent Hyperbilirubinemia
Recruiting
The proposed study will incorporate an intervention previously un-studied in the US healthcare setting for prevention of hyperbilirubinemia
Gender:
All
Ages:
Between 0 hours and 48 hours
Trial Updated:
06/13/2023
Locations: University of California-Davis, Sacramento, California
Conditions: Newborn Jaundice
Cannabis Use, Cognition, and the Endocannabinoid System in HIV
Recruiting
Understanding how co-morbidities in persons with HIV (PWH) such as substance use affect risk-taking, decision-making, and other cognitive behaviors is important given implications for everyday functioning and transmission risk. The high prevalence of cannabis use in PWH, medicinally and recreationally, may indicate disease severity, impart therapeutic benefits, or adverse consequences. In fact, cannabis is recommended to those with HIV to alleviate nausea, improve appetite, relieve pain, and lif... Read More
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
06/13/2023
Locations: UC San Diego Medical Center-Hillcrest, San Diego, California
Conditions: HIV-1-infection
Ashwagandha for Cognitive Dysfunction
Recruiting
This is a 1:1 randomized double blinded placebo controlled trial. • To determine if ashwagandha can improve cognitive dysfunction when compared with placebo in patients undergoing chemotherapy for cancer.
Gender:
All
Ages:
18 years and above
Trial Updated:
06/13/2023
Locations: Sutter Cancer Center, Sacramento, California
Conditions: Chemo Fog
Pembrolizumab in Treating Participants With Leukoplakia
Recruiting
This phase II pilot trial studies how well pembrolizumab works in treating leukoplakia. Monoclonal antibodies, such as pembrolizumab, may interfere with the ability of tumor cells to grow and spread.
Gender:
All
Ages:
18 years and above
Trial Updated:
06/13/2023
Locations: UC San Diego Moores Cancer Center, La Jolla, California
Conditions: Erythroleukoplakia, Leukoplakia, Verrucous Oral Leukoplakia
A Study of Vibegron in Pediatric Participants 2 Years to Less Than (<) 18 Years of Age With NDO and on CIC
Recruiting
The purpose of this study is to evaluate the safety, efficacy, and PK of vibegron in pediatric participants with NDO who are regularly using CIC
Gender:
All
Ages:
Between 2 years and 17 years
Trial Updated:
06/12/2023
Locations: Children's Hospital of Orange County, Orange, California
Conditions: Neurogenic Detrusor Overactivity
Gabapentin to Reduce Opioid Use Postoperatively (GROUP) in Children
Recruiting
The primary objective of this study is to determine if the peri and post operative use of gabapentin in children reduces the need for narcotics after thoracic surgery. We hypothesize that patients who are given gabapentin will need fewer morphine equivalents postoperatively than those who were not given gabapentin
Gender:
All
Ages:
17 years and below
Trial Updated:
06/12/2023
Locations: UC Davis Medical Center, Sacramento, California
Conditions: Pain, Postoperative
Infant Mortality Reduction by the Mass Administration of Azithromycin
Recruiting
This trial will investigate the supplementation of azithromycin distribution to the "Child Health Days" platform in Burkina Faso for child mortality reduction. This distribution will pair door-to-door administration of vitamin A and azithromycin or placebo with acute malnutrition screening among children 1-11 months old.
Gender:
All
Ages:
Between 1 month and 11 months
Trial Updated:
06/12/2023
Locations: University of California, San Francisco, San Francisco, California
Conditions: Child Mortality
Functional and Cognitive Rehabilitation of Hoarding Disorder
Recruiting
Hoarding Disorder (HD) is serious and disabling in Veterans. Present in up to 7% of Veterans and even higher symptom rates in older Veterans; HD contributes to functional impairment and poor quality of life. Cognitive Rehabilitation and Exposure/Sorting Therapy (CREST) has shown promising functional improvement and symptom reduction. To reduce burdens and barriers to implementation of CREST, the proposed project will individualize CREST based on cognitive testing and participant preferences, pro... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
06/12/2023
Locations: VA San Diego Healthcare System, San Diego, CA, San Diego, California
Conditions: Hoarding Disorder
In-Utero Endoscopic Correction of Spina Bifida
Recruiting
The purpose of this study is to evaluate the feasibility and effectiveness of performing fetoscopic surgical correction of fetal spina bifida. Two surgical approaches will be utilized: the percutaneous technique versus the laparotomy/uterine exteriorization technique.
Gender:
Female
Ages:
Between 18 years and 52 years
Trial Updated:
06/12/2023
Locations: Hollywood Presbyterian Medical Center, Los Angeles, California
Conditions: Neural Tube Defects, Spina Bifida, Myelomeningocele
Supracondylar Post-Operative Pain Study
Recruiting
The purpose of this study to investigate post-operative pain control in pediatric patients with closed supracondylar humerus fracture who undergo closed reduction and percutaneous pinning. Currently, it is standard of care that patients receive a narcotic prescription for post-operative pain control. All patients will initially be seen in our pediatric urgent care and recruited at the time of surgery. Patients will be randomized to receiving acetaminophen and ibuprofen or acetaminophen and oxyco... Read More
Gender:
All
Ages:
Between 5 years and 12 years
Trial Updated:
06/12/2023
Locations: Orthopaedic Institute for Children, Los Angeles, California
Conditions: Supracondylar Humerus Fracture
Effectiveness of Embrace Scar Therapy Device After Cutaneous Wound Closure
Recruiting
The purpose of this study is to determine whether the use of the embrace device after repair of linear cutaneous surgery wounds improves scar cosmesis.
Gender:
All
Ages:
18 years and above
Trial Updated:
06/12/2023
Locations: University of California, Davis, Department of Dermatology, Sacramento, California
Conditions: Linear Cutaneous Wound