California is currently home to 5931 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Los Angeles, San Francisco, San Diego and Sacramento. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Fruit and Vegetable Biomarker Discovery
Recruiting
The purpose of this research is to find a set of markers in the blood and/or urine that can be linked to consumption of specific fruits and vegetables. This will allow for better understanding of the link between diet and health-related outcomes. Furthermore, the results of this study will lead to the development of new methods to evaluate the nutritional status of individuals in both community and clinical settings. Food frequency questionnaires and diaries/recalls can be affected by intentiona... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/09/2023
Locations: USDA ARS Western Human Nutrition Research Center, Davis, California
Conditions: Biomarkers
Healthcare Providers as Trusted Messengers to Increase Receipt of Tax Credits Among Low-income Families
Recruiting
The purpose of this study is to pilot test the feasibility, acceptability, and preliminary efficacy of healthcare provider referrals to a tax filing app within parent-child health programs to test whether such referrals can increase receipt of tax credits among low-income parents. The study will use a single-group, pre/post test design with a sample of approximately 100 women who have a child under 6 years of age. Participants will be recruited from parental-child health programs and clinics in... Read More
Gender:
All
Ages:
Between 18 years and 99 years
Trial Updated:
05/09/2023
Locations: UCLA School of Nursing, Los Angeles, California
Conditions: Depression, Child Development, Stress, Physical Illness, Health Care Utilization
Mindfulness in Post Acute Sequelae of SARS-CoV-2 Infection (PASC) Dysautonomia
Recruiting
The current pilot study will recruit participants experiencing new, returning, or ongoing symptoms related to COVID-19 illness for at least four weeks after being first infected with SARS-CoV-2. All participants will attend a virtual 6-week course entitled Mindful Awareness Practices (MAPs) created, hosted and led by expert facilitators from the Mindful Awareness Research Center (MARC) at University of California Los Angeles (UCLA). This intervention will consist of a mix of lecture, practice, g... Read More
Gender:
Female
Ages:
Between 18 years and 54 years
Trial Updated:
05/09/2023
Locations: UCLA Health, Los Angeles, California
Conditions: Long COVID, Dysautonomia
COVID-19 Outcome Prediction Algorithm
Recruiting
Severe acute respiratory syndrome coronavirus 2-mediated coronavirus disease (COVID-19) is an evolutionarily unprecedented natural experiment that causes major changes to the host immune system. We propose to develop a test that accurately predicts short- and long-term (within one-year) outcomes in hospitalized COVID-19 patients broadly reflecting US demographics who are at increased risk of adverse outcomes from COVID-19 using both clinical and molecular data. We will enroll patients from a hos... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/09/2023
Locations: VA Greater Los Angeles Healthcare System, Los Angeles, California
Conditions: COVID-19, Post Acute Sequelae of COVID-19, Long COVID, Organ Dysfunction Syndrome, Multiple, Frailty Syndrome
The Expander-2 Trial: A Randomized Study to Evaluate the Safety and Efficacy of the Urocross(TM) Expander System and Retrieval Sheath
Recruiting
To demonstrate the safety and efficacy of the Urocross Expander System/Retrieval Sheath and the procedure to treat patients with symptomatic Benign Prostatic Hyperplasia (BPH).
Gender:
Male
Ages:
45 years and above
Trial Updated:
05/09/2023
Locations: Urology Associates of Silicon Valley, San Jose, California
Conditions: Benign Prostatic Hyperplasia
Modified Immune Cells (TAG72-CAR T Cells) for the Treatment of Patients With Platinum Resistant Epithelial Ovarian Cancer
Recruiting
This phase I trial tests the safety, side effects, and best dose of TAG72-chimeric antigen receptor (CAR) T cells in treating patients with epithelial ovarian cancer that remains despite treatment with platinum therapy (platinum resistant). T cells are infection fighting blood cells that can kill tumor cells. The T cells given in this study will come from the patient and will have a new gene put in them that makes them able to recognize TAG72, a protein on the surface of tumor cells. These TAG72... Read More
Gender:
Female
Ages:
18 years and above
Trial Updated:
05/09/2023
Locations: City of Hope Medical Center, Duarte, California
Conditions: Platinum-Resistant Ovarian Carcinoma
Impact of Time Restricted Eating on Patients With Coronary Artery Disease (CAD) Undergoing Cardiac Rehabilitation
Recruiting
The purpose of this study is to see if reducing the number of hours during which one eats each day will help reduce levels of LDL cholesterol and improve other markers of metabolic and cardiovascular health (i.e. blood sugar levels and blood pressure). The study also aims to assess changes in exercise capacity and trimethylamine N-oxide (TMAO) levels in response to Time Restricted Eating (TRE) and Intensive Cardiac Rehabilitation (ICR) versus ICR alone. TMAO is a metabolite, or a substance, prod... Read More
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
05/09/2023
Locations: Altman Clinical and Translational Research Institute, La Jolla, California
Conditions: Coronary Artery Disease
Parent Intervention for Psychiatrically-Hospitalized Youth
Recruiting
The purpose of the present study is to conduct a pilot randomized clinical trial (RCT) of a parent coaching intervention for parents of youth hospitalized for suicidal ideation, suicide attempt(s), or non-suicidal self-injury. Parents will receive either the parent coaching intervention (which includes safety planning and behavioral parenting skills training with a clinician and assistance with linkage to follow-up care by a case manager) or treatment as usual (TAU) for the inpatient unit. The l... Read More
Gender:
All
Ages:
Between 12 years and 85 years
Trial Updated:
05/09/2023
Locations: Michele Berk, Stanford, California
Conditions: Adolescent - Emotional Problem, Suicide and Self-harm, Parenting
Glycemic Targets for Pregnant Women With GDM and T2DM
Recruiting
The purpose of this randomized clinical trial is to determine whether glycemic targets that are lower than those currently recommended by the American Diabetes Association (ADA) and the American College of Obstetricians and Gynecologists (ACOG) would improve overall outcomes in pregnant patients with diabetes. Eligible pregnant women with a diagnosis of gestational diabetes or Type 2 diabetes will be randomized into either routine care with glycemic targets as currently recommended by ADA and AC... Read More
Gender:
Female
Ages:
18 years and above
Trial Updated:
05/09/2023
Locations: Los Angeles County + University of Southern California Medical Center (LAC+USC), Los Angeles, California
Conditions: Diabetes Mellitus in Pregnancy, Diabetes, Gestational, Diabetes Mellitus, Type 2
Pain and Opioids: Integrated Treatment In Veterans
Recruiting
This trial will recruit veterans with chronic pain (N = 160) who are prescribed buprenorphine for the treatment of opioid use disorder (OUD). We seek to: (1) examine the efficacy of an integrated treatment to reduce pain interference and substance misuse (Acceptance and Commitment Therapy and Mindfulness-Based Relapse Prevention [ACT + MBRP]) compared to an education control (EC) consisting of a protocol-based series of education sessions concerning chronic pain, opioids, and buprenorphine use a... Read More
Gender:
All
Ages:
Between 21 years and 75 years
Trial Updated:
05/09/2023
Locations: San Francisco VA Health Care System, San Francisco, California
Conditions: Chronic Pain, Opioid-use Disorder, Opioids; Harmful Use
Engaging Mothers & Babies; Reimagining Antenatal Care for Everyone (EMBRACE) Study
Recruiting
This is a randomized comparative effectiveness study of two forms of enhanced prenatal care among 2,600 Medi-Cal eligible pregnant women in Fresno, California. The goal is to see whether group prenatal care with wrap around services versus individual prenatal care supplemented by services covered by the California Department of Public Health Comprehensive Perinatal Services Program (CPSP) results in lower rates of preterm birth, less depression and anxiety, and more respectful and greater satisf... Read More
Gender:
Female
Ages:
All
Trial Updated:
05/09/2023
Locations: Central Valley Health Policy Institute, Fresno, California
Conditions: Premature Birth, Pregnancy Preterm, Prenatal Stress, Depression, Anxiety, Depression, Postpartum, Satisfaction, Patient, Health Problems in Pregnancy
PE Audit and Feedback Pilot Study
Recruiting
School physical education (PE) is one of the most valuable tools for increasing physical activity and fitness among youth of all backgrounds; however, compliance with existing PE laws is low (and differential by school race/ethnic and family-income composition, contributing to health disparities), and best practices for increasing compliance remain unknown. This study proposes to examine a novel approach for increasing PE law compliance by testing a PE audit and feedback tool (adapted from a too... Read More
Gender:
All
Ages:
All
Trial Updated:
05/08/2023
Locations: UC Berkeley, Berkeley, California
Conditions: Physical Inactivity, Cardiovascular Diseases