California is currently home to 5930 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Los Angeles, San Francisco, San Diego and Sacramento. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
A Unique Micro Water Jet Technology Device Versus Standard Debridement in the Treatment of Diabetic Foot
Recruiting
The purpose of this clinical investigation is to assess performance of the Medaxis Debritom+™ and to collect subject outcome data in the treatment of diabetic foot ulcers (DFU) vs Standard sharp debridement.
Gender:
All
Ages:
18 years and above
Trial Updated:
06/05/2023
Locations: CCR Research, San Francisco, California
Conditions: Diabetic Foot Ulcer, Diabetic Foot
Study of the Safety and Pharmacokinetics of BGB-283 (Lifirafenib) and PD-0325901 (Mirdametinib) in Participants With Advanced or Refractory Solid Tumors
Recruiting
This is a 2-part Phase 1b study of BGB-283 (lifirafenib) and PD-0325901 (mirdametinib) combination in participants with tumors.
Gender:
All
Ages:
18 years and above
Trial Updated:
06/05/2023
Locations: University of California Los Angeles, Santa Monica, California
Conditions: Solid Tumor, Adult
Video-Assisted Laryngoscopy Education
Recruiting
This study is designed to evaluate the impact of a video recording review on the acquisition of a new technical skill (laryngoscopy and tracheal intubation).
Gender:
All
Ages:
All
Trial Updated:
06/05/2023
Locations: University of California Davis, Sacramento, California
Conditions: Surgery
Register for Pediatric Patients With Antiphospholipid Syndrome (APS): European Project Extended Internationally Study
Recruiting
The purpose of this study is to gather information about causes and treatment of Antiphospholipid Syndrome.
Gender:
All
Ages:
Between 1 minute and 18 years
Trial Updated:
06/05/2023
Locations: UC Davis Medical Center, Sacramento, California
Conditions: Antiphospholipid Syndrome
Family Functioning in Obesity Treatment for Mexican Americans
Recruiting
Mexican American families share similar elevated risks for obesity and obesity-related conditions, such as type 2 diabetes. Because negative family interactions and relationships (e.g., poor communication, high conflict, low emotional closeness) are associated with obesity treatment outcomes, this study tests a behavioral weight management intervention that provides relationship skills counseling to mothers and adult daughters. The goal is to improve family interaction patterns to buffer challen... Read More
Gender:
Female
Ages:
Between 18 years and 65 years
Trial Updated:
06/04/2023
Locations: University of California San Diego, La Jolla, California
Conditions: Obesity
Evaluation of Neurocognitive Changes in Parkinson's Disease After Low Frequency Burst Stimulation
Recruiting
This study aims to determine whether direct brain stimulation of specific regions and ranges improves cognition in people with Parkinsons Disease (PD) who already have a deep brain stimulator implanted. Research activities consist of 32 subjects undergoing stimulation changes to their device and being administered neurocognitive tests to evaluate the changes. An fMRI scan will also be done at baseline and at weeks 15 and 27. All subjects will undergo the stimulation changes in a randomized doub... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
06/03/2023
Locations: University of Southern California Keck School of Medicine, Los Angeles, California
Conditions: Parkinson Disease
GCC19CART for Patients With Metastatic Colorectal Cancer
Recruiting
Study ICT-GCC19CART-US-001 (CARAPIA-1) is a Phase 1 study evaluating the safety, tolerability, clinical activity, pharmacokinetics and pharmacodynamics of GCC19CART in subjects with relapsed or refractory metastatic colorectal cancer.
Gender:
All
Ages:
18 years and above
Trial Updated:
06/02/2023
Locations: City of Hope Comprehensive Cancer Center, Duarte, California
Conditions: Colorectal Cancer
Study to Compare the Use of a Behavioral Health App Versus Care as Usual for 16-22 Year Olds With Depression
Recruiting
Randomized Controlled Trial comparing a coach-enhanced digital cognitive behavioral intervention (d-CBI) (RxWell) + treatment as usual (TAU) versus TAU alone for moderate depression as determined by Patient Health Questionnaire (PHQ-9) threshold as part of routine pediatric care. The study will be completed in pediatric practices with embedded behavioral therapists across 3 institutions (Children's Hospital of Pittsburgh, Boston Children's Hospital, Rady Children's Hospital, San Diego).
Gender:
All
Ages:
Between 16 years and 22 years
Trial Updated:
06/02/2023
Locations: Rady Children's Hospital - San Diego, San Diego, California
Conditions: Depression
Evaluating Treatment of ADHD in Children With Down Syndrome
Recruiting
Children with Down syndrome (DS) have a 3-5 time greater prevalence of Attention Deficit Hyperactivity Disorder (ADHD) than typically developing (TD) children. Despite this higher risk of ADHD, rates of stimulant medication treatment are disproportionately low in children with DS+ADHD, even though stimulants are the most efficacious ADHD treatment and are recommended by consensus guidelines for use in children with intellectual disability and ADHD. The investigators propose the first randomized... Read More
Gender:
All
Ages:
Between 6 years and 17 years
Trial Updated:
06/02/2023
Locations: University of California Davis MIND Institute, Sacramento, California
Conditions: Down Syndrome, ADHD
Treating Pediatric NAFLD With Nutrition
Recruiting
This is a proof of concept clinical trial to compare daily intake of at least 20 grams of whole dairy fat vs habitual diet on hepatic steatosis in children with NAFLD.
Gender:
All
Ages:
Between 10 years and 17 years
Trial Updated:
06/01/2023
Locations: UC San Diego, La Jolla, California
Conditions: Non-Alcoholic Fatty Liver Disease, Liver Diseases, Liver Fat, Hepatic Steatosis, Nutritional and Metabolic Disease
Evaluation of Autologous Natural Killer Cell Activity in Primary Cancer Cell Cultures
Recruiting
The objectives of the study is to evaluate the anti-tumor activity of autologous natural killer cells in cultures of cancer cells obtained from patient's own tumor.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/31/2023
Locations: Sarcoma Oncology Research Center, Santa Monica, California
Conditions: Sarcoma
Effects of Ashwagandha Extract (Capsule KSM-66 300 mg) on Sexual Health in Healthy Women
Recruiting
The clinical study aims to evaluate Efficacy and Safety of KSM66 Ashwagandha Standardized Root Extract for Improving Sexual Health in Healthy Women by measuring the sex hormone levels in blood, analyzing results of questionnaires, and monitoring adverse events in the post-marketing phase. Changes in sex hormone levels in blood may affect sexual health or sexual health satisfaction. Efficacy is defined as increase in sex hormone levels in blood, and improvements in results or scores in assessment... Read More
Gender:
Female
Ages:
Between 18 years and 55 years
Trial Updated:
05/31/2023
Locations: San Francisco Research Institute, San Francisco, California
Conditions: Sexual Health