California is currently home to 5605 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Los Angeles, San Francisco, San Diego and Sacramento. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Advanced Spatiomotor Rehabilitation for Navigation in Blindness & Visual Impairment
Recruiting
One of the most challenging tasks for blind and visually impaired individuals is navigation through a complex environment. The goal of the present multidisciplinary study is to increase spatial-cognition abilities in people who are blind or visually impaired through training with the previously-developed Cognitive-Kinesthetic Rehabilitation Training to improve navigation, and to investigate the resultant neuroplastic brain reorganization through multimodal brain imaging. In accordance with Nati... Read More
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
11/20/2023
Locations: Smith-Kettlewell Eye Research Institute, San Francisco, California
Conditions: Blindness, Blindness, Acquired, Low Vision, Blindness, Complete
Encoding Temporal Fine Structure for Cochlear Implants
Recruiting
The goal of this study is to improve music and speech perception for cochlear implant users. Presently, most cochlear implants discard the temporal fine structure of sound, which is information that is widely believed to contribute to both music and speech perception. The proposed work examines perceptual and physiological changes that occur once this information is provided to cochlear implant users in a clear and consistent manner.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/20/2023
Locations: University of Southern California, Los Angeles, California
Conditions: Hearing Loss, Cochlear Implants
Music Appreciation After Cochlear Implantation
Recruiting
This project aims to characterize the emergence of music appreciation in people who have suffered hearing loss and have been provided with partial restoration of hearing through cochlear implantation. Music appreciation is complex and transverses multiple domains including hearing acuity, speech and language acquisition, and quality of life. By studying these relationships in people who have been given partial hearing restoration, the investigators will clarify the role of music for promoting re... Read More
Gender:
ALL
Ages:
13 years and above
Trial Updated:
11/20/2023
Locations: Keck School of Medicine of USC, Los Angeles, California
Conditions: Hearing Loss, Cochlear Implants
TLI, TBI, ATG & Hematopoietic Stem Cell Transplantation and Recipient T Regs Therapy in Living Donor Kidney Transplantation
Recruiting
This study will determine whether a preparatory regimen including total lymphoid irradiation (TLI), total body irradiation (TBI), anti-thymocyte globulin (ATG) and infusion of the donor hematopoietic stem cells when given along with recipient regulatory T cells (Tregs) will allow for eventual discontinuation of anti-rejection drugs after living donor kidney transplantation.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
11/20/2023
Locations: Stanford University, Palo Alto, California
Conditions: Living Donor Kidney Transplantation
Prevention of Postop Atrial Fibrillation Through Intraoperative Inducibility of Atrial Fibrillation and Amiodarone Treatment
Recruiting
Patients undergoing first time cardiac surgery will undergo rapid atrial pacing prior to initiation of cardiopulmonary bypass to screen for AF inducibility. Patients with inducible AF will be randomized to prophylactic amiodarone treatment versus no treatment. Patients who are not inducible to AF will be treated with standard post-operative care. Patients will be monitored post-operatively to explore the value of intraoperative inducibility of AF to predict POAF and to evaluate whether the combi... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/20/2023
Locations: Stanford University, Stanford, California
Conditions: Postoperative Atrial Fibrillation
COMParison of Algorithms for Rotational Evaluation in Atrial Fibrillation
Recruiting
This is a cohort study to evaluate algorithms for mapping atrial fibrillation by mapping atrial structure and mapping electrical activity to detect focal and rotational activity.
Gender:
ALL
Ages:
Between 21 years and 90 years
Trial Updated:
11/20/2023
Locations: Stanford University, Stanford, California
Conditions: Atrial Fibrillation, Abnormal Heart Rhythms
International Lymphatic Disease and Lymphedema Registry
Recruiting
The purpose of the International Lymphatic Disease and Lymphedema Patient Registry and Biorepository is to collect health information in order to study the disease classification, natural history, and impact of Lymphatic Disease, Lymphedema and Related Disorders and its treatments and medical outcomes.
Gender:
ALL
Ages:
All
Trial Updated:
11/20/2023
Locations: Stanford University School of Medicine, Stanford, California
Conditions: Lymphedema
Prospective Database Registry Study of Scoliosis in Children With Cerebral Palsy
Recruiting
The purpose of this study is to determine the radiographic and clinical outcomes of Scoliosis surgical and non-operative treatment in patients with Cerebral Palsy.
Gender:
ALL
Ages:
Between 8 years and 21 years
Trial Updated:
11/20/2023
Locations: Rady Children's Hospital, San Diego, California
Conditions: Cerebral Palsy, Scoliosis
The Pediatric Anesthesia Quality Improvement Project
Recruiting
The Study is designed to collect information about adverse events that occur in children undergoing anesthesia in participating hospitals. Demographic information will be collected on all anesthetics. An analysis of each adverse event will be performed and entered into the database. From this information we will devise strategies to prevent these adverse events.
Gender:
ALL
Ages:
21 years and below
Trial Updated:
11/20/2023
Locations: Children's Hospital Los Angeles, Los Angeles, California
Conditions: Surgery, Anesthesia, Children
The PALSUR-study: Palliative Care Versus Surgery in High-grade Glioma Patients (ENCRAM 2203)
Recruiting
There is no consensus on the optimal treatment of patients with high-grade glioma, especially when patients have limited functioning performance at presentation (KPS ≤70). Therefore, there are varied practice patterns around pursuing biopsy, resection, or palliation (best supportive care). This study aims to characterize the impact of palliative care versus biopsy versus resection on survival and quality of life in these patients. Also, it will aim to determine if there is a subset of patients t... Read More
Gender:
ALL
Ages:
Between 18 years and 90 years
Trial Updated:
11/18/2023
Locations: University of California, San Francisco, San Francisco, California
Conditions: Glioblastoma, Glioblastoma Multiforme, Glioblastoma, IDH-wildtype, Glioblastoma Multiforme, Adult
The RESBIOP-study: Resection Versus Biopsy in High-grade Glioma Patients (ENCRAM 2202)
Recruiting
There are no guidelines or prospective studies defining the optimal surgical treatment for gliomas of older patients (≥70 years) or those with limited functioning performance at presentation (KPS ≤70). Therefore, the decision between resection and biopsy is varied, amongst neurosurgeons internationally and at times even within an instiutition. This study aims to compare the effects of maximal tumor resection versus tissue biopsy on survival, functional, neurological, and quality of life outcomes... Read More
Gender:
ALL
Ages:
Between 18 years and 90 years
Trial Updated:
11/18/2023
Locations: University of California, San Francisco, San Francisco, California
Conditions: Glioblastoma, Glioblastoma, IDH-wildtype, Glioblastoma Multiforme, Glioblastoma Multiforme, Adult, Glioblastoma Multiforme of Brain
Use of Virtual and Augmented Reality Devices in Vestibular Physical Therapy for mTBI
Recruiting
Rapidly evolving virtual reality (VR) and augmented reality (AR) technologies are being incorporated by many large-scale industries, and the medical field is no exception. One area that has gained significant attention in recent years is virtual rehabilitation which allows physical therapists to leverage state-of-the-art immersive virtual environments to uniquely address functional deficits in patients who are unresponsive to conventional treatment techniques. Advanced VR and AR technologies are... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
11/17/2023
Locations: Naval Health Research Center, San Diego, California
Conditions: MTBI - Mild Traumatic Brain Injury, Dysfunction of Vestibular System