California is currently home to 5930 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Los Angeles, San Francisco, San Diego and Sacramento. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
JAB-3312 Based Combination Therapy in Adult Patients With Advanced Solid Tumors
Recruiting
To evaluate the safety and tolerability of JAB-3312 administered in investigational regimens in adult participants with advanced solid tumors.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/16/2023
Locations: Research Site, Los Angeles, California
Conditions: Solid Tumor, NSCLC
Fermented Food-Supplemented Diet in Ulcerative Colitis
Recruiting
The purpose of this study is to see how a diet that supplements fermented foods effects inflammation and quality of life in patients with mild to moderate Ulcerative Colitis (UC). There is a paucity of research and an enormous need for better understanding of diet and intestinal inflammation. Fermented food have been shown to positively influence inflammatory cytokines and intestinal microbial diversity in healthy volunteers.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/16/2023
Locations: Stanford University, Palo Alto, California
Conditions: Inflammatory Bowel Diseases, Diet Modification, Ulcerative Colitis
PrecISE (Precision Interventions for Severe and/or Exacerbation-Prone Asthma) Network Study
Recruiting
The primary objective of this study is to evaluate several interventions given to participants with severe asthma. Interventions are administered in a crossover manner with 16-week treatment periods followed by 8 to 16 week washout.
Gender:
All
Ages:
12 years and above
Trial Updated:
05/16/2023
Locations: University of California Davis, Sacramento, California
Conditions: Asthma
Patient Derived Vascularized MicroTumor Model of Gastrointestinal Peritoneal Carcinomatosis
Recruiting
This is a pilot study gathering and using samples and data from patients with gastrointestinal peritoneal carcinomatosis. Participants will be asked for permission to provide blood and ascites/peritoneal wash fluid, tumor samples during their planned surgical procedure.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/15/2023
Locations: Chao Family Comprehensive Cancer Center, University of California, Irvine, Orange, California
Conditions: Peritoneal Carcinomatosis, Gastrointestinal Peritoneal Carcinomatosis
18F-F-AraG PET Imaging to Evaluate Immunological Response to CAR T Cell Therapy in Lymphoma
Recruiting
This is a pilot study in adult subjects with aggressive B-cell lymphoma who will receive commercial or research CAR T cell therapy as anticancer treatment.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/15/2023
Locations: Stanford University, School of Medicine, Stanford, California
Conditions: Non-Hodgkin's Lymphoma
Using Nicotine to Reverse Age-related Auditory Processing Deficits
Recruiting
The present study will evaluate the effects of both aging and nicotine on psychophysical tasks and electrophysiological measures. Nicotine will be administered to study participants in the form of gum that is available as an over-the-counter medication. The hypothesis is that nicotine will reverse the detrimental effects of aging on auditory processing. The proposed experiments will characterize the effects of nicotine and may eventually lead to improved treatments of hearing loss in a variety o... Read More
Gender:
All
Ages:
Between 18 years and 85 years
Trial Updated:
05/15/2023
Locations: Hearing and Speech Lab, Irvine, California
Conditions: Auditory Perceptual Impairment, Aging
Pharmacologic Weight Loss as Adjunct Therapy for Ulcerative Colitis in Obese Patients
Recruiting
Approximately 20-40% of patients with ulcerative colitis (UC) are obese. The investigators have demonstrated that obesity adversely impacts disease course in patients with UC, leading to higher risk of persistently active disease, surgery, hospitalization, and treatment failure, particularly in biologic-treated patients. Intentional weight loss is effective in improving disease outcomes in patients with inflammatory arthritis, but there is limited data on its impact in UC. While dietary interven... Read More
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
05/12/2023
Locations: University of California San Diego, La Jolla, California
Conditions: Colitis, Ulcerative, Obesity
Continuous Glucose Monitoring in Infants
Recruiting
The purpose of this study is to employ continuous glucose monitoring to measure glucose profiles in newborn infants.
Gender:
All
Ages:
Between 1 hour and 2 hours
Trial Updated:
05/12/2023
Locations: UCSD Medical Center, La Jolla, California
Conditions: Neonatal Hypoglycemia
SKY Breath Intervention
Recruiting
Depression is highly debilitating and prevalent among adolescents. Adolescent-onset depression is associated with long, severe, and recurrent episodes that are often not responsive to treatment. There is a dire need to develop novel treatments that are efficient, cost-effective, and tolerant for this population. Sudarshan Kriya Yoga (SKY) is a breath-based meditative practice that entails a sequence of specific breathing techniques to help practitioners achieve a state of calm alertness. It has... Read More
Gender:
All
Ages:
Between 16 years and 24 years
Trial Updated:
05/11/2023
Locations: University of California, San Francisco, San Francisco, California
Conditions: Depression, Anxiety Disorders
Secondhand Tobacco Smoke and Cardiovascular Disease
Recruiting
This is a double-blind randomized placebo-controlled crossover clinical trial of efficacy and safety of an FDA-approved angiotensin receptor blocker (losartan) to improve cardiopulmonary outcomes in individuals with pre-Chronic Obstructive Pulmonary Disease (COPD) due to prolonged exposure to secondhand tobacco smoke.
Gender:
All
Ages:
40 years and above
Trial Updated:
05/11/2023
Locations: San Francisco Veterans' Affairs Medical Center, San Francisco, California
Conditions: Cardiovascular Diseases, Hypertension
Lower Extremity BFR-randomized Controlled Trial Healthy Volunteers
Recruiting
The purpose of this research is to determine the effects of low-load blood flow restriction (BFR) training compared to conventional strengthening using dynamic force plate and isometric force frame analyses in healthy subjects.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/10/2023
Locations: Cedar Sinai Kerlan jobe orthopedic institute, Los Angeles, California
Conditions: Healthy
A Study in Participants With Mild-to-moderate Systemic Lupus Erythematosus
Recruiting
The main purpose of this study is to evaluate the safety and tolerability of CUG252 following multiple ascending doses in participants with Systemic Lupus Erythematosus (SLE).
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
05/10/2023
Locations: Site 1011, La Jolla, California
Conditions: Systemic Lupus Erythematosus, SLE (Systemic Lupus), Autoimmune