California is currently home to 5930 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Los Angeles, San Francisco, San Diego and Sacramento. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Individualized Neuroimaging Biomarkers for Predicting rTMS Response in OCD
Recruiting
The goal of this clinical trial is to discover brain-based subtypes of Obsessive Compulsive Disorder (OCD) and examine treatment response to two different repetitive transcranial magnetic stimulation (rTMS) targets in the brain: the medial prefrontal cortex (MPFC) and the right prefrontal cortex (rPFC).
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
05/10/2023
Locations: Stanford University, Stanford, California
Conditions: Obsessive-Compulsive Disorder
Extension Study of Oral PHA-022121 for Acute Treatment of Angioedema Attacks in Patients With Hereditary Angioedema
Recruiting
This study evaluates the safety and efficacy of long-term on-demand treatment with orally administered deucrictibant for acute hereditary angioedema (HAE) attacks, including laryngeal attacks, in patients with HAE due to C1-esterase inhibitor (C1-INH) deficiency (type I/II). The study will enroll patients from Study PHA022121-C201 (NCT04618211) who elect to participate in this extension study and meet the eligibility requirements.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/10/2023
Locations: Study site, Walnut Creek, California
Conditions: Hereditary Angioedema, Hereditary Angioedema Type I, Hereditary Angioedema Type II, Hereditary Angioedema Types I and II, Hereditary Angioedema Attack, Hereditary Angioedema With C1 Esterase Inhibitor Deficiency, Hereditary Angioedema - Type 1, Hereditary Angioedema - Type 2, C1 Esterase Inhibitor [C1-INH] Deficiency, C1 Esterase Inhibitor Deficiency, C1 Esterase Inhibitor, Deficiency of, C1 Inhibitor Deficiency
Family Mental Health Family Navigator Project (FMHN)
Recruiting
This study will focus on developing and testing a family-based mental health navigator intervention, the Family Mental Health Navigator (FMHN), to evaluate whether the intervention combined with mHealth is preliminary efficacious in improving mental health service initiation and engagement for publicly-insured youth.
Gender:
All
Ages:
Between 6 years and 17 years
Trial Updated:
05/10/2023
Locations: UCSF Zuckerberg San Francisco General Hospital, San Francisco, California
Conditions: Mental Health
Foster Care Mental Health Family Navigator
Recruiting
This study will focus on developing and testing a family-based mental health navigator intervention, the Foster Care Family Navigator (FCFN), to evaluate whether the intervention combined with mHealth would be efficacious in improving mental health service initiation and engagement for child welfare-involved youth.
Gender:
All
Ages:
Between 12 years and 17 years
Trial Updated:
05/10/2023
Locations: UCSF Zuckerberg San Francisco General Hospital, San Francisco, California
Conditions: Mental Health
Duration of Urinary Catheterization
Recruiting
This study is being conducted to determine the length of time a urinary catheter is needed to drain urine from the bladder after colorectal surgery. Urinary retention is a well known complication after pelvic colorectal surgery, and current practice is to continue urinary catheterization for 3- days following pelvic colorectal surgery in an effort to avoid this complication. However, prolonged urinary catheterization is associated with increased risk of urinary tract infections as well as longer... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/10/2023
Locations: Keck Hospital of USC, Los Angeles, California
Conditions: Colorectal Surgery
Dementia and Diabetes Prevention Program
Recruiting
This is a multicenter, randomized 2-arm clinical trial of two lifestyle interventions varying in intensity and format, in 400 older African American and non-Hispanic whites at increased risk of cognitive decline and dementia in the East San Francisco Bay Area. The trial will include two lifestyle interventions that differ in intensity and format: Aerobic Exercise (AEx) Intervention that involves aerobic activities with in-class walking workouts and tutorials and carried out at the East Oakland... Read More
Gender:
All
Ages:
60 years and above
Trial Updated:
05/10/2023
Locations: University of California, Davis Alzheimer's Disease Center, Walnut Creek, California
Conditions: Diabetes, Dementia
Use of CXCL9 as a Biomarker of Acthar Efficacy
Recruiting
The objective is this study is to test whether use of Acthar gel in the context of sarcoidosis will lead to improved symptoms and lung function and correlate with decreased levels of predictive blood biomarkers, like chemokine ligand 9 (CXCL9).
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
05/10/2023
Locations: University of California, San Francisco, San Francisco, California
Conditions: Sarcoidosis
Healthcare Providers as Trusted Messengers to Increase Receipt of Tax Credits Among Low-income Families
Recruiting
The purpose of this study is to pilot test the feasibility, acceptability, and preliminary efficacy of healthcare provider referrals to a tax filing app within parent-child health programs to test whether such referrals can increase receipt of tax credits among low-income parents. The study will use a single-group, pre/post test design with a sample of approximately 100 women who have a child under 6 years of age. Participants will be recruited from parental-child health programs and clinics in... Read More
Gender:
All
Ages:
Between 18 years and 99 years
Trial Updated:
05/09/2023
Locations: UCLA School of Nursing, Los Angeles, California
Conditions: Depression, Child Development, Stress, Physical Illness, Health Care Utilization
COVID-19 Outcome Prediction Algorithm
Recruiting
Severe acute respiratory syndrome coronavirus 2-mediated coronavirus disease (COVID-19) is an evolutionarily unprecedented natural experiment that causes major changes to the host immune system. We propose to develop a test that accurately predicts short- and long-term (within one-year) outcomes in hospitalized COVID-19 patients broadly reflecting US demographics who are at increased risk of adverse outcomes from COVID-19 using both clinical and molecular data. We will enroll patients from a hos... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/09/2023
Locations: VA Greater Los Angeles Healthcare System, Los Angeles, California
Conditions: COVID-19, Post Acute Sequelae of COVID-19, Long COVID, Organ Dysfunction Syndrome, Multiple, Frailty Syndrome
The Expander-2 Trial: A Randomized Study to Evaluate the Safety and Efficacy of the Urocross(TM) Expander System and Retrieval Sheath
Recruiting
To demonstrate the safety and efficacy of the Urocross Expander System/Retrieval Sheath and the procedure to treat patients with symptomatic Benign Prostatic Hyperplasia (BPH).
Gender:
Male
Ages:
45 years and above
Trial Updated:
05/09/2023
Locations: Urology Associates of Silicon Valley, San Jose, California
Conditions: Benign Prostatic Hyperplasia
Impact of Time Restricted Eating on Patients With Coronary Artery Disease (CAD) Undergoing Cardiac Rehabilitation
Recruiting
The purpose of this study is to see if reducing the number of hours during which one eats each day will help reduce levels of LDL cholesterol and improve other markers of metabolic and cardiovascular health (i.e. blood sugar levels and blood pressure). The study also aims to assess changes in exercise capacity and trimethylamine N-oxide (TMAO) levels in response to Time Restricted Eating (TRE) and Intensive Cardiac Rehabilitation (ICR) versus ICR alone. TMAO is a metabolite, or a substance, prod... Read More
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
05/09/2023
Locations: Altman Clinical and Translational Research Institute, La Jolla, California
Conditions: Coronary Artery Disease
Parent Intervention for Psychiatrically-Hospitalized Youth
Recruiting
The purpose of the present study is to conduct a pilot randomized clinical trial (RCT) of a parent coaching intervention for parents of youth hospitalized for suicidal ideation, suicide attempt(s), or non-suicidal self-injury. Parents will receive either the parent coaching intervention (which includes safety planning and behavioral parenting skills training with a clinician and assistance with linkage to follow-up care by a case manager) or treatment as usual (TAU) for the inpatient unit. The l... Read More
Gender:
All
Ages:
Between 12 years and 85 years
Trial Updated:
05/09/2023
Locations: Michele Berk, Stanford, California
Conditions: Adolescent - Emotional Problem, Suicide and Self-harm, Parenting