California is currently home to 5930 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Los Angeles, San Francisco, San Diego and Sacramento. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
The Hancock Jaffe Surgical Antireflux Venous Valve Endoprosthesis Study
Recruiting
A prospective, non blinded, single arm, multicenter study designed to assess the safety and effectiveness of the bioprosthetic, VenoValve, which is surgically implanted into the deep venous system for treatment of patients with deep venous valvular insufficiency ( C4b-C6 patients).
Gender:
All
Ages:
18 years and above
Trial Updated:
04/04/2023
Locations: Cedars-Sinai Medical Center, Beverly Hills, California
Conditions: Deep Venous Insufficiency (Diagnosis)
Accuracy of Ultrasound for Detecting Residual Fragments During RIRS
Recruiting
The purpose of this study is to assess the accuracy of ultrasound and traditional fluoroscopy to find the residual fragments before retrograde intrarenal surgery is complete. This would ultimately limit the need for radiation exposure and improve the quality of clinical care given to patients and healthcare teams.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/03/2023
Locations: University of California, San Francisco, San Francisco, California
Conditions: Stone, Kidney, Ultrasound Therapy; Complications
Enhancing BodyWorks: A Canine Health Literacy Module
Recruiting
Dog ownership can serve as a vehicle for large-scale multi-level public health interventions, especially for pediatric overweight and obesity, due to dogs' unique place in children and adolescents' social networks.This study develops and tests a novel approach to design a Canine Health-Literacy module to enhance a Comprehensive Family Lifestyle Intervention BodyWorks, for dog-owning adolescents who have been diagnosed with overweight or obesity, and their parents. The results are anticipated to... Read More
Gender:
All
Ages:
Between 9 years and 17 years
Trial Updated:
04/03/2023
Locations: AltaMed@CHLA, Los Angeles, California
Conditions: Overweight and Obesity, Overweight Adolescents
Development of Radiation Free Whole Body Magnetic Resonance (MR) Imaging Technique for Staging Children With Cancer
Recruiting
A research study on the diagnosis of spread of disease for children who have been diagnosed with solid tumors using a new whole body imaging technique and a new MR contrast agent (ferumoxytol). Standard tests that are used to determine the extent and possible spread of a child's disease include magnetic resonance (MR) imaging, computed tomography (CT), Positron Emission Tomography (PET) as well as bone scanning, and metaiodobenzylguanidine (MIBG) scanning. The purpose of this study is to determi... Read More
Gender:
All
Ages:
Between 6 years and 40 years
Trial Updated:
04/03/2023
Locations: Stanford University Cancer Institute, Stanford, California
Conditions: Cancer
Sperm Preparation Prior to Intrauterine Insemination Study
Recruiting
This is a randomized controlled trial comparing density gradient centrifugation and microfluidic sperm sorting in patients undergoing intrauterine insemination to evaluate cumulative pregnancy outcomes.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/30/2023
Locations: UCSF Center for Reproductive Health, San Francisco, California
Conditions: Infertility, Infertility Secondary, Infertility Unexplained, Anovulation, Fertility Disorders, Reproductive Issues
Noninvasive Spinal Neuromodulation Enables Locomotor Recovery in Individuals With Cerebral Palsy
Recruiting
Assessing the effects of noninvasive spinal cord neuromodulation on improving function in individuals with cerebral palsy
Gender:
All
Ages:
Between 2 years and 75 years
Trial Updated:
03/30/2023
Locations: SpineX, Los Angeles, California
Conditions: Cerebral Palsy
C-myc Biomarker Study for Diabetic Foot Ulcers
Recruiting
This is a multi-center observational cohort study of patients with diabetic foot ulcers (DFU) to develop and validate potential tissue-based biomarkers that predict complete wound healing. Eligible and consented participants will begin standard of care treatment after collection of tissue specimens from the wound's edge. An additional tissue specimen is collected at 4 weeks if clinically indicated. Tissues will be tested for c-myc and phosphorylated glucocorticoid receptor (p-GR) levels using va... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
03/29/2023
Locations: University of California - San Francisco, San Francisco, California
Conditions: Diabetes, Diabetic Foot, Diabetic Foot Ulcer, Diabetic Wound
Multicenter Clinical Study of the SING-IMT in Patients With Late-stage AMD
Recruiting
The objective of this study is to determine the safety and effectiveness of the smaller incision, new generation (SING), implantable miniature telescope (IMT) in patients with moderate-severe central vision loss due to late-stage age-related macular degeneration (AMD).
Gender:
All
Ages:
65 years and above
Trial Updated:
03/28/2023
Locations: Loma Linda University, Loma Linda, California
Conditions: Age-Related Macular Degeneration, Geographic Atrophy
Clinical Trial of BP1001 in Combination With With Venetoclax Plus Decitabine in AML
Recruiting
The primary objectives of this study are to assess: (1) whether the combination of BP1001 plus venetoclax plus decitabine provides greater efficacy (Complete Remission [CR], Complete Remission with incomplete hematologic recovery [CRi], Complete Remission with partial hematologic recovery [CRh], than venetoclax plus decitabine alone (by historical comparison) in participants with untreated AML that cannot or elect not to be treated with more intensive chemotherapy; (2) whether BP1001-based treat... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
03/27/2023
Locations: UCLA Medical Center, Los Angeles, California
Conditions: Acute Myeloid Leukemia (AML)
Blue Light Cystoscopy With Cysview® Registry
Recruiting
Registry study to gather more information on the current use of Blue Light Cystoscopy with Cysview (BLCC) in urologists' practices.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/27/2023
Locations: USC/Norris Comprehensive Cancer Center, Los Angeles, California
Conditions: Bladder Cancer
Study of ANX005 in Adults With Amyotrophic Lateral Sclerosis (ALS)
Recruiting
This study is a multi-center, open-label study of intravenous (IV) ANX005 in participants with ALS.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/23/2023
Locations: Annexon Investigational Site 01, Orange, California
Conditions: Amyotrophic Lateral Sclerosis
Computerized Tests of Cognitive Decline in Presymptomatic Alzheimer's Disease
Recruiting
The investigators will study performance on computerized cognitive tasks in healthy participants of different ages to gather normative data for newly developed computerized cognitive tests. These tests are designed to permit the early detection of individuals at risk of age-related cognitive decline.
Gender:
All
Ages:
Between 18 years and 89 years
Trial Updated:
03/22/2023
Locations: Neurobehavioral Systems, Inc., Berkeley, California
Conditions: Alzheimer Disease, Aging, Cognitive Decline