California is currently home to 5625 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Los Angeles, San Francisco, San Diego and Sacramento. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Effects of Voluntary Adjustments During Walking in Participants Post-stroke
Recruiting
People post-stroke retain the capacity to modify walking patterns explicitly using biofeedback and implicitly when encountering changes in the walking environment. This proposal will assess changes in muscle activation patterns associated with walking modifications driven explicitly vs. implicitly, to determine whether individuals generate different amounts of co-contraction during explicit vs. implicit walking modifications. Understanding how walking modifications driven explicitly vs. implicit... Read More
Gender:
ALL
Ages:
Between 18 years and 90 years
Trial Updated:
09/11/2023
Locations: Chapman University, Irvine, California
Conditions: Stroke
The Efficacy and Safety of Bonjesta® for Nausea and Vomiting of Pregnancy in Pregnant Adolescents
Recruiting
The primary objective of this study is to compare the efficacy of Bonjesta for the treatment of nausea and vomiting of pregnancy (NVP) in pregnant adolescents aged 12 to 17 years with placebo. The secondary objective of this study is to compare the safety of Bonjesta in pregnant adolescents aged 12 to 17 years with placebo.
Gender:
FEMALE
Ages:
Between 12 years and 17 years
Trial Updated:
09/08/2023
Locations: Velvet Clinical Research, Burbank, California
Conditions: Morning Sickness
Primary Cytoreductive Surgery With or Without Hyperthermic Intraperitoneal Chemotherapy (HIPEC)
Recruiting
stage III epithelial ovarian cancer randomizing between primary cytoreductive surgery with or without hyperthermic intraperitoneal chemotherapy
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
09/07/2023
Locations: City of Hope, Duarte, California
Conditions: Ovarian Cancer
Study of 3D Scanning for Adolescent Scoliosis
Recruiting
The investigators aim to validate three-dimensional topographical scanning technology as a tool for evaluation of scoliosis. Through the incorporation of 3D topographical technology in the measurement of deformity, the investigators hope to validate a novel approach to quantify deformity progression and provide an accessible alternative to traditional radiographic workup.
Gender:
ALL
Ages:
Between 10 years and 18 years
Trial Updated:
09/06/2023
Locations: Stanford University School of Medicine, Palo Alto, California
Conditions: Scoliosis
Treatment Recommendations for Gastrointestinal Cancers Via Large Language Models
Recruiting
This study will evaluate the utility of ChatGPT in recommending treatment plans for patients with gastrointestinal cancers, using both retrospective and prospective data.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/06/2023
Locations: City of Hope, Duarte, California
Conditions: Gastrointestinal Neoplasm Malignant
The Cedars-Sinai Smidt Heart Institute Takotsubo Registry & Proteomic Study
Recruiting
The Cedars-Sinai SHI Takotsubo Registry and Proteomic Study is an observational registry that will collect retrospective and prospective demographic, clinical, hemodynamic, laboratory and other diagnostic parameters, therapy and outcome data from individuals who meet the inclusion/exclusion criteria of Takotsubo Registry protocol. Subjects will also be invited to provide a blood sample utilizing a Mitra kit sent to their homes. Researchers from the Barbra Streisand Women's Heart Center will anal... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/06/2023
Locations: Cedars Sinai Medical Center, Los Angeles, California
Conditions: Takotsubo Cardiomyopathy
Diode Laser as a Biomarker for Neuropathic Pain of Peripheral Origin.
Recruiting
The R61 will perform a four-part double-blind randomized crossover study transitioning from a pretreatment baseline phase, to randomized treatment with either lidocaine or an identical placebo patch, washout, and alternate arm. DLss measures will be obtained before and after each phase. Twice daily report of pain using a visual analogue scale will track severity of ongoing spontaneous pain in participants. The hybrid biomarker will distinguish between placebo and active treatment arms, will sign... Read More
Gender:
ALL
Ages:
Between 18 years and 69 years
Trial Updated:
09/05/2023
Locations: Stanford University, Palo Alto, California
Conditions: Peripheral Neuropathy
Bacteriophage Therapy in Patients With Diabetic Foot Osteomyelitis
Recruiting
This is a phase IIa randomized trial designed to evaluate bacteriophage therapy in patients with diabetic foot osteomyelitis.
Gender:
ALL
Ages:
Between 18 years and 85 years
Trial Updated:
09/05/2023
Locations: NorthBay Healthcare, Fairfield, California
Conditions: Osteomyelitis, Diabetic Foot Osteomyelitis
Fluad vs. Fluzone High-Dose Vaccine Effectiveness Among Adults ≥65 Years
Recruiting
This study will evaluate the relative vaccine effectiveness of quadrivalent adjuvanted inactivated influenza vaccine (aIIV4) versus quadrivalent high-dose inactivated influenza vaccine (HD-IIV4) in preventing polymerase chain reaction (PCR)-confirmed influenza and influenza-related outcomes in adults ≥65 years of age during the 2023/24 and 2024/25 influenza seasons. The study is an observational study conducted at Kaiser Permanente Northern California (KPNC), an integrated health care system in... Read More
Gender:
ALL
Ages:
65 years and above
Trial Updated:
09/01/2023
Locations: Kaiser Permanente Northern California (entire region), Oakland, California
Conditions: Influenza, Community-acquired Pneumonia, Cardiovascular Events
Adherence to Different Exercise Interventions
Recruiting
Only 50% of sedentary adults that start an exercise training program adhere to the program after 6 months. Exercise variety may improve adherence. The goal of this study is to examine different exercise interventions that include a variety of exercise on adherence.
Gender:
ALL
Ages:
Between 18 years and 40 years
Trial Updated:
09/01/2023
Locations: California Polytechnic State University, San Luis Obispo, California
Conditions: Exercise Adherence
Semaglutide Treatment in the Real-world for Fibrosis Due to NAFLD in Obesity and T2DM
Recruiting
Conduct a community intervention study that will 1) validate a screening approach to identify patients at risk for advanced NAFLD in the obese or T2DM population, and 2) test whether semaglutide treatment is effective for the management of significant fibrosis due to NAFLD in high-risk patients.
Gender:
ALL
Ages:
Between 40 years and 79 years
Trial Updated:
09/01/2023
Locations: University of California, San Diego, La Jolla, California
Conditions: Fibrosis, Liver, Type 2 Diabetes Mellitus in Obese, Non-Alcoholic Fatty Liver Disease
A Phase 3 Study to Investigate the Efficacy and Safety of SHR0302 With Moderately to Severely Active Ulcerative Colitis
Recruiting
This is a randomized, double-blind, placebo-controlled, multicenter Phase 3 study that will enroll approximately 368 subjects aged 18 to 75 years old with Moderately to Severely Active Ulcerative Colitis.
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
09/01/2023
Locations: Om Research LLC, Lancaster, California
Conditions: Ulcerative Colitis