California is currently home to 5602 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Los Angeles, San Francisco, San Diego and Sacramento. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Defense and Veterans Center for Integrative Pain Management (DVCIPM) Pain Registry Biobank
NCT04004286
Recruiting
This Pain Registry Biobank is a prospective cohort design study whereby data (PASTOR survey, blood and saliva specimens, clinical data) is collected from participants in a longitudinal fashion with continual enrollment.
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
08/10/2023
Locations: Naval Medical Center San Diego, San Diego, California
Conditions: Pain
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An Open-label, Single-dose Study to Evaluate Safety, Tolerability, and Pharmacokinetics of Brodalumab in Pediatric Subjects
NCT03240809
Recruiting
An Open-label, Single-dose Study to Evaluate Safety, Tolerability, and Pharmacokinetics of Brodalumab in Pediatric Subjects
Gender:
ALL
Ages:
Between 6 years and 18 years
Trial Updated:
08/09/2023
Locations: Bausch Site 003, San Diego, California
Conditions: Psoriasis
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Long Term Efficacy of Neuronavigation Guided rTMS in Alleviating Gulf War Illness Related Headaches and Pain Symptoms
NCT04182659
Recruiting
This study aims to look at the long term efficacy of using repetitive transcranial magnetic stimulation (rTMS) in relieving Gulf War Illness related headaches and pain.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
08/07/2023
Locations: VA Palo Alto, Palo Alto, California
Conditions: Gulf War Syndrome, Gulf War Illness, Headache, Muscle Pain, Joint Pain
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The Effect of Guided Care With Vectra Compared to Treatment as Usual in Patients With Rheumatoid Arthritis
NCT03631225
Recruiting
The goal of treating patients diagnosed with rheumatoid arthritis (RA) is to achieve remission or low disease activity and thereby prevent joint damage, loss of physical function, and disability. Optimal management requires regular assessment of disease activity, with treatment changes made as needed for optimal efficacy. Vectra is a blood serum test that looks at 12 biomarkers and produces a score on a scale of 1 to 100. The Vectra score has been shown to be the strongest predictor of risk for... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/07/2023
Locations: Bio Solutions Clinical Research, La Mesa, California
Conditions: Rheumatoid Arthritis (RA)
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Low-Intensity Focused Ultrasound Pulsation (LIFUP) for the Treatment of Generalized Anxiety Disorder (GAD)
NCT04557891
Recruiting
There are few treatment options available for patients once they have failed standard psychopharmacological therapy for generalized anxiety disorder. Existing brain stimulation methods such as rTMS fail to target deep brain structures associated with anxiety disorders; structures such as the amygdala. In this double-blind sham-controlled clinical trial, the investigators propose to establish baseline severity of anxiety in 48 patients, then deliver eight treatments over four sessions of focused... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
08/04/2023
Locations: University of California, Los Angeles, Los Angeles, California
Conditions: Generalized Anxiety Disorder
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A Study of Voruciclib Alone or in Combination With Venetoclax in Subjects With B-Cell Malignancies or AML
NCT03547115
Recruiting
This is a Phase 1, open-label, dose escalation study to determine the safety and preliminary efficacy of voruciclib monotherapy in subjects with relapsed/refractory B cell malignancies or AML after failure of standard therapies or voruciclib in combination with venetoclax in subjects with relapsed or refractory AML
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/03/2023
Locations: City of Hope, Duarte, California
Conditions: Follicular Lymphoma (FL), Mantle Cell Lymphoma (MCL), Marginal Zone Lymphoma (MZL), Small Lymphocytic Lymphoma (SLL), Chronic Lymphocytic Leukemia (CLL), Diffuse Large B-cell Lymphoma (DLBCL), Acute Myeloid Leukemia (AML)
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Venetoclax and Lintuzumab-Ac225 in AML Patients
NCT03867682
Recruiting
The study is a multicenter, open label Phase I/II trial. 1. To determine the maximum tolerated dose (MTD) of lintuzumab-Ac225 added to venetoclax for patients with CD33 positive relapsed/refractory AML. (Phase 1 portion) 2. To assess the percentage of patients with CR, CRh, or Overall Response (CR + CRh), up to 6 months after the start of treatment without receiving other AML therapies. (Phase 2 portion)
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/02/2023
Locations: University of California, Los Angeles, California
Conditions: Acute Myeloid Leukemia, Relapsed Adult AML
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Groningen International Study on Sentinel Nodes in Vulvar Cancer-III
NCT05076942
Recruiting
Vulvar cancer patients with SN-metastasis \> 2mm will receive chemoradiation instead of an inguinofemoral lymphadenectomy.
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
07/27/2023
Locations: UC Irvine Health/Chao Family Comprehensive Cancer Center, Orange, California
Conditions: Vulvar Cancer, Sentinel Lymph Node, Lymph Node Metastases
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A Safety and Pharmacokinetics Study of IDP-122 Lotion in Pediatric Participants With Plaque Psoriasis
NCT03987763
Recruiting
This study is to evaluate the safety, the systemic exposure of halobetasol propionate (HP), and the hypothalamic-pituitary-adrenal (HPA) axis suppression potential for topically applied IDP-122 lotion in pediatric participants with moderate to severe plaque psoriasis.
Gender:
ALL
Ages:
Between 6 years and 17 years
Trial Updated:
07/25/2023
Locations: Bausch Site 11, Fountain Valley, California
Conditions: Psoriasis
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Oral Supplementation of Astaxanthin on Skin Photoaging, Hydration and Elasticity
NCT05882084
Recruiting
This study is a double-blind placebo controlled study to assess whether oral astaxanthin can improve skin hydration, skin elasticity, improve skin pigmentation, and reduce facial redness.
Gender:
FEMALE
Ages:
Between 30 years and 55 years
Trial Updated:
07/24/2023
Locations: Integrative Skin Science and Research, Sacramento, California
Conditions: Photoaging
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Dose Regimen Study of SLI-F06 in Healthy Volunteers
NCT05501327
Recruiting
Multi-center, dose-regimen, double-blind study evaluating the safety and efficacy of 4 doses of SLI-F06 compared with vehicle for improvement in scar appearance
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
07/24/2023
Locations: California Dermatology & Clinical Research Institute, Encinitas, California
Conditions: Scar, Wound Healing
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The Association of Microbiome Patterns With Chronic Opioid Use
NCT05304403
Recruiting
The United States is in the midst of an opioid epidemic, with the number of opioid-related deaths having risen six-fold since 1999. Chronic pain imposes a tremendous economic burden of up to US$635 billion per year in terms of direct costs (such as the costs of treatment) and indirect costs (such as lost productivity and time away from work). We need to better understand individual characteristics that may put patients at risk for chronic opioid use. Recently, the relationship between gut microb... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/24/2023
Locations: University of California San Diego, La Jolla, California
Conditions: Chronic Pain, Opioid Use
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