California is currently home to 5591 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Los Angeles, San Francisco, San Diego and Sacramento. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
EXPLORER Total Body PET/CT Imaging for Myofascial Pain
Recruiting
The main objective of this study is to establish novel measures derived from Total-body-Positron Emission Tomography/Computed Tomography (TB-PET/CT) as quantitative biomarkers for the investigation of myofascial pain. The TB-PET/CT assessed measures are those reflective of myofascial tissue metabolism, perfusion, and fatty infiltration.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/16/2025
Locations: University of California Davis Health, Sacramento, California
Conditions: Myofascial Pain
A Phase 1 Study of ZL-1218 in Subjects With Advanced Solid Tumors
Recruiting
The purpose of this study is to characterize the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD), and preliminary antitumor activity of ZL-1218 as a single agent and as combination therapy in subjects with advanced solid tumor malignancies.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/16/2025
Locations: Zai Lab Site 2005, Irvine, California
Conditions: Malignant Solid Tumor
ARX788 in HER2-positive, Metastatic Breast Cancer Subjects (ACE-Breast-03)
Recruiting
A Global, Phase 2 Study of ARX788 in HER2-positive Metastatic Breast Cancer Patients who were previously treated with T-DXd
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/16/2025
Locations: Research Site, Los Angeles, California
Conditions: HER2 Positive Metastatic Breast Cancer
Trial of 225Ac-DOTATATE (RYZ101) in Subjects with ER+, HER2-negative Unresectable or Metastatic Breast Cancer Expressing SSTRs.
Recruiting
Phase 1b/2 open-label trial of 225Ac-DOTATATE (RYZ101) in subjects with ER+, HER2-negative unresectable or metastatic breast cancer expressing SSTRs.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/15/2025
Locations: Research Facility, Irvine, California
Conditions: Metastatic Breast Cancer, HER2-negative Breast Cancer, ER+ Breast Cancer, Advanced Breast Cancer
IGNITE Firefighters' Health
Recruiting
Investigators hope to learn about potential dietary intervention strategies (specifically a whole-food, plant-based diet) that may help lower cancer markers in firefighters.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/15/2025
Locations: Stanford University, Palo Alto, California
Conditions: Cancer, Inflammation, Microbiome, Immune Function
Enhancing Transdiagnostic Mechanisms of Cognitive Dyscontrol (R33)
Recruiting
The proposed project aims to test the cognitive and neural effects of a cognitive training in a sample of individuals seeking treatment for anxiety, depression, or traumatic stress symptoms. Participants will be randomly assigned to one of two groups. Group 1 will receive a computer-based program that is designed as a cognitive training intervention and Group 2 will receive a similar computer-based exercise that researchers think will be less effective in training thinking skills (also known as... Read More
Gender:
ALL
Ages:
Between 21 years and 55 years
Trial Updated:
01/15/2025
Locations: UC San Diego, San Diego, California
Conditions: Anxiety Disorders, Depression, Post Traumatic Stress Disorder
Managing Kyphosis With Exercise
Recruiting
The primary objective of this study is to determine if stretching exercises as a conservative treatment option will correct kyphosis in postural and Scheuermann's kyphosis.
Gender:
ALL
Ages:
8 years and above
Trial Updated:
01/15/2025
Locations: Cedars-Sinai Medical Center, Los Angeles, California
Conditions: Kyphosis
Effect of Group Preoperative Pelvic Floor Training for HoLEP
Recruiting
The main goal of this study is to see if group pelvic floor training before surgery can help prevent urinary incontinence after Holmium laser enucleation of the prostate (HoLEP) surgery. The study has the potential to inform preoperative intervention strategies for managing incontinence after HoLEP.
Gender:
MALE
Ages:
Between 50 years and 90 years
Trial Updated:
01/15/2025
Locations: University of California, San Francisco, San Francisco, California
Conditions: BPH, Urinary Incontinence
UPURS Trial for Patient-centered Management of Symptomatic Obstructing Stones
Recruiting
A prospective, non-blinded, randomized controlled trial studying the management of symptomatic ureteral stones. This study will compare upfront ureteroscopy vs observation and delayed intervention for patients presenting to the emergency department with a symptomatic ureteral stone.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/15/2025
Locations: University of California, San Francisco, San Francisco, California
Conditions: Ureteral Stone
Latinos Understanding the Need for Adherence in Diabetes Using E-Health
Recruiting
Latinos Understanding the Need for Adherence in Diabetes using Care Coordination, Integrated Medical and Behavioral Care and E-Health (LUNA-E) is a randomized controlled trial (RCT) that will test the effectiveness a patient-centered, team-based, primary care intervention with E-Health enhancements in improving glycemic control (primary outcome, hemoglobin A1C level) and psychological distress (secondary outcome; depression, anxiety symptoms).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/15/2025
Locations: South Bay Latino Research Center, Chula Vista, California
Conditions: Type 2 Diabetes, Glycemic Control, Psychological Distress
A Study of Ivaltinostat Plus Capecitabine or Capecitabine in Metastatic Pancreatic Adenocarcinoma
Recruiting
This study is a Phase 1b/2, dose-escalation, randomized, multicenter study to assess the efficacy, safety, tolerability, and PK of ivaltinostat in combination with capecitabine and capecitabine monotherapy in patients with metastatic pancreatic adenocarcinoma whose disease has not progressed on a first line fluoropyrimidine-based chemotherapy (e.g., FOLFIRINOX). In Phase 1b, 3 dose levels of ivaltinostat will be studied in combination with a fixed dose of capecitabine to determine the RP2D of i... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/15/2025
Locations: Hoag Medical Group, Newport Beach, California
Conditions: Metastatic Pancreatic Adenocarcinoma
Molecular Autopsy Study
Recruiting
This study seeks to incorporate genetic testing into the postmortem examination of cases of sudden unexplained death.
Gender:
ALL
Ages:
45 years and below
Trial Updated:
01/15/2025
Locations: Scripps Translational Science Institute, La Jolla, California
Conditions: Sudden Unexplained Death