California is currently home to 5599 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Los Angeles, San Francisco, San Diego and Sacramento. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Enhancing Team Effectiveness for a Collaborative School-based Intervention for ADHD
Recruiting
The proposed project aims to integrate team-based implementation strategies with an established school-based intervention for children with ADHD, the Collaborative Life Skills Program (CLS), to enhance its implementation and optimize its effectiveness. The investigators will tailor three empirically-supported team development interventions, Team Charters, Team Communication Training (Student Handoff Protocols), and Team Performance Monitoring, and integrate them into a team-enhanced CLS implemen... Read More
Gender:
ALL
Ages:
Between 7 years and 11 years
Trial Updated:
04/11/2024
Locations: IN STEP Children's Mental Health Center, San Diego, California
Conditions: Team-effectiveness Research, School-based Interventions, Attention Deficit/ Hyperactivity Disorder, Implementation Science
Phase 1 Study of SON-1010 in Adult Patients With Advanced Solid Tumors
Recruiting
This is a Phase 1, first-in-human, open-label, adaptive-design outpatient study to assess the safety, tolerability, and PK/PD of SON-1010 administered to patients with advanced solid tumors.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/11/2024
Locations: Sarcoma Oncology Center, Santa Monica, California
Conditions: Advanced Solid Tumor
A Multi-Center Post-Market Data Collection Protocol to Evaluate the Performance of Orthofix Spine Devices
Recruiting
This protocol is designed to study Orthofix regulatory approved and commercially available spine devices to generate Real World Evidence (RWE) of device safety and performance in the treatment of patients with spine injuries and/or disorders following the local medical standard of care. The clinical data generated from this study will support compliance to global regulatory requirements including but not limited to the European Medical Device Regulation (EU MDR) for the applicable devices.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/11/2024
Locations: Lanman Spinal Neurosurgery, Beverly Hills, California
Conditions: Spinal Disorders/Injuries
Effects of Nicotine and Attention on Frequency Tuning in Auditory Cortex
Recruiting
Nicotine enhances auditory-cognitive function because it mimics the brain's system for "paying attention" to important sounds amid distractions (for example, understanding speech in a noisy environment). In part, nicotine does this by activating inhibitory neurons in the auditory cortex. Since age-related hearing deficits result, in part, from the loss of inhibitory neurons in auditory cortex, this project will determine whether nicotine's effects can compensate for reduced inhibition in the agi... Read More
Gender:
ALL
Ages:
Between 18 years and 85 years
Trial Updated:
04/11/2024
Locations: University of California, Berkeley, Berkeley, California
Conditions: Aging
Eversense® Non-adjunctive Use Post Approval Study
Recruiting
This is a non-blinded, prospective, multi-center, single arm longitudinal cohort study (patient serving as their own control), to evaluate the effectiveness of diabetes with the Eversense CGM System non-adjunctively compared to self-monitoring of blood glucose (SMBG) using a blood glucose (BG) meter in participants with either Type 1 or Type 2 diabetes. Subjects will serve as their own control, with their baseline based on using SMBG to manage their diabetes for the first 6 months followed by us... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/11/2024
Locations: LA Universal Research Center, Inc., Los Angeles, California
Conditions: Diabetes
Intravenous Iron Versus Oral Iron for the Treatment of Iron Deficiency Anemia
Recruiting
This study aims to assess whether administering intravenous iron early in pregnancy, compared to standard oral iron treatment, can enhance hemoglobin levels before delivery and reduce the need for blood transfusions in patients with iron deficiency anemia. Patients diagnosed with iron deficiency anemia were randomly assigned to receive either oral or intravenous iron. Before treatment initiation, patients completed a symptom questionnaire baseline hemoglobin, and ferritin levels were measured. F... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
04/10/2024
Locations: Arrowhead Regional Medical Center, Colton, California
Conditions: Iron Deficiency Anemia of Pregnancy
Intermittent Fasting on Body Fat and Quality of Life
Recruiting
The purpose of this investigator-initiated study to check the feasibility that intermittent fasting has on body fat loss and quality of life.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
04/10/2024
Locations: Loma Linda University, Loma Linda, California
Conditions: Healthy
Neural and Cognitive Consequences of COVID-19 Survival
Recruiting
The novel coronavirus SARS-CoV-2 infection, COVID, continues to rage throughout the world with 115,000,000 confirmed cases and over 2,500,000 deaths (as of Mar 3, 2021). This translates to millions of people surviving COVID19 infection. While the lungs are ground zero, COVID tears through organ systems from brain to blood vessels. We are now beginning to see people recover but complain of ongoing problems, including lingering cognitive problems, depression, and anxiety. We have brought together... Read More
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
04/10/2024
Locations: San Francisco Heathcare System, San Francisco, California
Conditions: COVID Long-Haul, COVID-19, COVID-19 Pandemic, Brain Fog, Memory Deficits, Concentration Ability Impaired, Fatigue
Targeting Access and Knowledge of Earned Income Tax Credit (EITC) Utilization and Policies
Recruiting
The earned income tax credit (EITC) is the largest United States poverty alleviation program, providing up to $6,600 for working families as a tax refund. Prior studies have shown the EITC's benefits for social outcomes and health. Effects are even more significant for single mothers and Black women. Despite these known benefits, 20%-33% of eligible individuals do not receive benefits, leaving $7 billion unclaimed annually. The Targeting Access and Knowledge of EITC Utilization and Policies (TAK... Read More
Gender:
FEMALE
Ages:
Between 18 years and 64 years
Trial Updated:
04/10/2024
Locations: California Special Supplemental Nutrition Program for Women, Infants, and Children (WIC), Sacramento, California
Conditions: Mental Health Issue, Food Security, Well-being
Bumetanide in Patients With Alzheimer's Disease
Recruiting
This study aims to investigate bumetanide in patients with biologically confirmed Alzheimer's disease (AD). Bumetanide is a potent diuretic administered orally and is FDA approved for the treatment of edema and hypertension. Repurposing bumetanide as a medication for AD has been proposed based on data that demonstrated its ability to "flip" the APOE genotype-dependent transcriptomic signatures in AD mouse and cell culture models. Critically, this discovery was subsequently explored in Electronic... Read More
Gender:
ALL
Ages:
Between 50 years and 85 years
Trial Updated:
04/10/2024
Locations: Stanford University, Stanford, California
Conditions: Alzheimer Disease
Long-Term Follow-Up of Patients Who Have Participated in Children's Oncology Group Studies
Recruiting
This clinical trial keeps track of and collects follow-up information from patients who are currently enrolled on or have participated in a Children's Oncology Group study. Developing a way to keep track of patients who have participated in Children's Oncology Group studies may allow doctors learn more about the long-term effects of cancer treatment and help them reduce problems related to treatment and improve patient quality of life.
Gender:
ALL
Ages:
All
Trial Updated:
04/10/2024
Locations: Kaiser Permanente Downey Medical Center, Downey, California
Conditions: Hematopoietic Cell Transplantation Recipient, Leukemia, Solid Tumor
Safety and Feasibility of Umbilical Cord Wharton's Jelly Allograft Injections for Lumbar Pain
Recruiting
This is a Pilot Study that is an open label, prospective, non-controlled study in which the safety and feasibility of Wharton's Jelly (WJ) allograft will be evaluated in 100 participants suffering with low back pain.
Gender:
ALL
Ages:
20 years and above
Trial Updated:
04/09/2024
Locations: R3 Anti Aging Beverly Hills, Beverly Hills, California
Conditions: Low Back Pain