California is currently home to 5930 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Los Angeles, San Francisco, San Diego and Sacramento. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Evaluating a Dropless Postoperative Regimen After Cataract Surgery in a Vulnerable, County-hospital Population
Recruiting
The current postoperative cataract surgery eye drop regimen used at Zuckerberg San Francisco General Hospital (ZSFG) is a significant burden for its patient population, contributing to high rates of non-adherence and the development of postoperative complications. The investigators propose to replace this complex regimen with a single administration of intraocular antibiotic and subconjunctival steroid at the time of surgery. This pilot study will obtain the preliminary data required to eventual... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
06/27/2023
Locations: Zuckerberg San Francisco General Hospital and Trauma Center (ZSFG), San Francisco, California
Conditions: Cataract, Surgery, Compliance, Patient, Compliance, Medication, Satisfaction, Patient
A Study of Codrituzumab in Children and Young Adults With Solid Tumors and Have Not Responded to Treatment or Have Come Back After Treatment
Recruiting
The purpose of this study to find out whether codrituzumab is a safe treatment that causes few or mild side effects in children and young adults who have solid tumors that express the protein GPC3. The researchers also want to study the way codrituzumab is absorbed, distributed, and cleared from the body.
Gender:
All
Ages:
Between 1 year and 21 years
Trial Updated:
06/27/2023
Locations: Children's Hospital of Los Angeles (Data Collection Only), Los Angeles, California
Conditions: Primary Extra-cranial Solid Tumor, Recurrent or Refractory Glypican 3 (GPC3)
Backpack Weight Impacts
Recruiting
Backpacking is an increasingly popular outdoor recreational activity. The base pack weight (BPW) includes gear that is not consumed or worn on the body: shelter, sleep system, weather-proofing layers and personal gear to ensure a degree of comfort and safety. As such, reducing BPW is one of the most important tasks a backpacker manages when preparing for a trip. Available recommendations for ideal BPW are currently inconsistent, lack clear parameters, and rely on anecdotal evidence. The study ai... Read More
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
06/27/2023
Locations: UCSF Fresno, Fresno, California
Conditions: Exertion; Excess
Transpacific TAVR Registry
Recruiting
This registry evaluates the long-term outcome of Transcatheter aortic valve replacement (TAVR) in real-world clinical practice.
Gender:
All
Ages:
19 years and above
Trial Updated:
06/27/2023
Locations: Stanford University, Stanford, California
Conditions: Heart Valve Diseases, Aortic Valve Insufficiency
Transarterial Chemoembolization for the Treatment of Lung Cancer
Recruiting
This phase II trial evaluates how well transarterial chemoembolization (TACE) works for treating patients with non-small cell lung cancer. TACE is a minimally invasive procedure that involves injecting chemotherapy directly into an artery that supplies blood to tumors, and then blocking off the blood supply to the tumors. Mitomycin (chemotherapy), Lipiodol (drug carrier), and Embospheres (small plastic beads that block off the artery) are injected into the tumor-feeding artery. This traps the ch... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
06/26/2023
Locations: City of Hope Medical Center, Duarte, California
Conditions: Lung Non-Small Cell Carcinoma, Mediastinal Neoplasm, Pleural Neoplasm
Luteolin for the Treatment of People With Schizophrenia
Recruiting
Luteolin is a natural product found in foods such as celery, green pepper, parsley, and chamomile tea. It has been found to have anti-cancer, anti-oxidant, and anti-inflammatory properties. The purpose of this study is to determine if luteolin helps improve symptoms of schizophrenia.
Gender:
All
Ages:
Between 18 years and 60 years
Trial Updated:
06/26/2023
Locations: University of California, Los Angeles, Los Angeles, California
Conditions: Schizophrenia, Schizoaffective Disorder
A Silver Lining in the VAD Sky
Recruiting
The investigators propose to conduct a prospective randomized trail (RCT) of a driveline management protocol. The study will be initiated at UCSF from January 1st 2022 to December 31st 2022 as a pilot to be extended to other sites with the ultimate goal to develop a multi-center RCT. The driveline dressing protocol studied will include a silver-based dressing barrier as well as a dressing change protocol and material designed to reduce the risk of driveline dressing induced dermatitis and allerg... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
06/26/2023
Locations: UCSF Parnassus, San Francisco, California
Conditions: LVAD (Left Ventricular Assist Device) Driveline Infection
Evaluate the Continued Safety and Performance of the Foot and Ankle Products
Recruiting
The objective of the registry is to evaluate the continued safety and performance of the Arthrex foot and ankle products including the ProStop implant for hyperpronated foot, Bio-Compression Screw for reconstruction surgeries of the foot, TRIM-IT Drill Pin, TRIM-IT Spin Pin for fixation of fractures and fusion (bunionectomy osteotomies) of the foot/ankle, Headless Compression Screws and Compression FT Screws for fixation of small bone fragments of the foot/ankle and DynaNite® Nitinol Staple to b... Read More
Gender:
All
Ages:
2 years and above
Trial Updated:
06/26/2023
Locations: UC Davis Medical Center, Sacramento, California
Conditions: Hyperpronated Foot, Reconstruction Surgeries of the Foot, Fixation of Fractures and Fusion (Bunionectomy Osteotomies) of the Foot/Ankle, Fixation of Small Bone Fragments of the Foot/Ankle, Lisfranc Arthrodesis, Mono or Bi-cortical Osteotomies in the Forefoot, First Metatarsophalangeal Arthrodesis, Akin Osteotomy, Midfoot and Hindfoot Arthrodeses or Osteotomies, Fixation of Osteotomies for Hallux Valgus Treatment (Scarf and Chevron), Arthrodesis of the Metatarsocuneiform Joint to Reposition and Stabilize Metatarsus Primus Varus, Osteotomy Fixation of Hallux Valgus Repair (Such as Scarf and Chevron Etc.)
Social & Contextual Impact on Children Undergoing Liver Transplantation
Recruiting
The social determinants of health have a large impact on health. For example, neighborhood socioeconomic deprivation is associated with increased risk of medication non-adherence, graft failure, and death in children after liver transplant. In order to address these socioeconomic inequities in outcomes, a more granular understanding of how the social determinants of health impact outcomes is needed. In this observational prospective cohort, caregivers of children undergoing liver transplantation... Read More
Gender:
All
Ages:
70 years and below
Trial Updated:
06/26/2023
Locations: Children's Hospital Los Angeles, Los Angeles, California
Conditions: Liver Transplantation, Liver Diseases
18FluoroLDOPA PET Imaging for the Detection and Localization of Focal Congenital Hyperinsulinism
Recruiting
The goal of this project is to determine the role of FDOPA/PET as a pre-operative diagnostic imaging procedure for differentiating focal and diffuse forms of congenital hyperinsulinism and locating focal lesions in the pancreas to guide surgical resection.
Gender:
All
Ages:
Between 0 days and 18 years
Trial Updated:
06/26/2023
Locations: University of California, San Francisco, San Francisco, California
Conditions: Congenital Hyperinsulinism
ARrest RESpiraTory Failure From PNEUMONIA
Recruiting
This research study seeks to establish the effectiveness of a combination of an inhaled corticosteroid and a beta agonist compared to placebo for the prevention of acute respiratory failure (ARF) in hospitalized patients with pneumonia and hypoxemia.
Gender:
All
Ages:
18 years and above
Trial Updated:
06/26/2023
Locations: Stanford University, Palo Alto, California
Conditions: Pneumonia, Hypoxemia, Acute Respiratory Failure, COVID-19 Pneumonia
Packing Versus no Packing for Cutaneous Abscess
Recruiting
The goal of this study is to examine patients undergoing incision and drainage of cutaneous abscesses to determine if routine packing of the abscess cavity affects the need for further interventions such as repeat incision and drainage, antibiotic administration or hospital admission.
Gender:
All
Ages:
18 years and above
Trial Updated:
06/26/2023
Locations: Community Regional Medical Center, Fresno, California
Conditions: Cutaneous Abscess