California is currently home to 5602 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Los Angeles, San Francisco, San Diego and Sacramento. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Determination and Validation of a Multi-analyte Assay for Lung Cancer Screening
Recruiting
This study is part of the development and validation of a non-invasive lung screening test which aim to identify early stage lung cancer in patients at high risk for lung cancer.
Gender:
ALL
Ages:
Between 50 years and 80 years
Trial Updated:
03/28/2024
Locations: Scripps Memorial Hospital, Encinitas, California
Conditions: Lung Cancer
PRT for Adolescents With High Functioning Autism
Recruiting
The purpose of this study is to identify improvement in behavioral and social function and changes in the brain following Pivotal Response Treatment (PRT) for Adolescents in highly verbal adolescents with autism spectrum disorder (ASD).
Gender:
ALL
Ages:
Between 11 years and 14 years
Trial Updated:
03/26/2024
Locations: Stanford Research Park, Palo Alto, California
Conditions: Autism, Autism Spectrum Disorder High-Functioning, Developmental Disability, Child Development, Behavior, Child, Behavior, Social
Modulation of SERCA2a of Intra-myocytic Calcium Trafficking in Heart Failure With Reduced Ejection Fraction
Recruiting
It is believed that targeted SERCA2a enzyme replacement in HFrEF patients will correct defective intracellular Ca2+ hemostasis, resulting in improved cardiac contractile function and energetics which will, in turn, translate to improved clinical outcomes. Additionally, it is hypothesized that correcting SERCA2a dysfunction will also improve coronary blood flow through correction of the impaired endothelium-dependent nitric oxide-mediated vasodilatation observed in heart failure.
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
03/24/2024
Locations: San Diego Cardiac Center, San Diego, California
Conditions: Congestive Heart Failure, Heart Failure, Systolic, Heart Failure, HFrEF - Heart Failure With Reduced Ejection Fraction
Optimizing Engagement in Services for First-Episode Psychosis
Recruiting
This study will compare a 12-session behavioral activation (BA) intervention modified for first-episode psychosis (FEP) to usual community mental health care (i.e., treatment-as-usual; TAU) delivered over 6 months with a sample of Latinos with FEP and their families. Comparable family group sessions will also be delivered to participants in both conditions. It is expected that BA participants will show better engagement than TAU participants.
Gender:
ALL
Ages:
Between 15 years and 35 years
Trial Updated:
03/22/2024
Locations: San Fernando Mental Health Center, Granada Hills, California
Conditions: Engagement, Patient, First Episode Psychosis
A Novel, Comprehensive Approach to Post-stroke Gait Rehabilitation
Recruiting
The goal of this project is to determine the feasibility and optimal parameters of a novel, comprehensive approach to gait training in individuals with chronic stroke. The comprehensive approach includes biofeedback-based gait training and aerobic exercise intensity-based gait training.
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
03/22/2024
Locations: University of Southern California, Los Angeles, California
Conditions: CVA (Cerebrovascular Accident)
Motion Delos: An Open Label Safety and Efficacy of Tradipitant in Participants Affected by Motion Sickness
Recruiting
An open label study to investigate the safety and efficacy of tradipitant in participants affected by motion sickness during travel
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
03/20/2024
Locations: Santa Monica Clinical Trials, Santa Monica, California
Conditions: Motion Sickness
Evaluating the Effects of Tasimelteon in Individuals With Autism Spectrum Disorder (ASD) and Sleep Disturbances
Recruiting
This is a multicenter, open-label study to evaluate the efficacy and safety of a daily single oral dose of tasimelteon in treating sleep disturbances in pediatric and adult participants with ASD.
Gender:
ALL
Ages:
Between 2 years and 65 years
Trial Updated:
03/19/2024
Locations: Vanda Investigational Site, San Jose, California
Conditions: Autism Spectrum Disorder, Sleep Disorder, Neurological Disorder, Sleep Disturbance
A Study of BTX-A51 in People With Relapsed or Refractory Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome
Recruiting
This is an open-label, dose escalation study to evaluate the safety, toxicity, and pharmacokinetics (PK) as well as preliminary efficacy of BTX-A51 capsules in participants with relapsed or refractory acute myeloid leukemia (AML) or high-risk myelodysplastic syndrome (MDS). The study will be done in three parts. Part 1a (Monotherapy Dose Escalation) of this study is designed to determine the dose-limiting toxicities (DLTs) and maximum tolerated dose (MTD) of orally administered BTX-A51 in up to... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/19/2024
Locations: City of Hope National Medical Center, Duarte, California
Conditions: Acute Myeloid Leukemia, Myelodysplastic Syndrome
Metastatic Tumor Research and Outcomes Network
Recruiting
The registry aims to collect patient information such as patient demographics, co-morbidities, clinical, diagnostic, and therapeutic data, as well as information on adverse events and HRQOL outcomes specific for patients with metastatic spine tumor(s).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/19/2024
Locations: University of California The UCSF Spine Center Department of Neurological Surgery, San Francisco, California
Conditions: Metastatic Spine Tumor
Primary Tumor Research and Outcomes Network
Recruiting
This project aims to establish a network of spine oncology centers dedicated to prospective multicenter research of patients diagnosed with a primary tumor of the spine and will include a comprehensive prospective clinical database which will serve as a shared research platform. Demographic, clinical, diagnostic, and therapeutic variables will be used to answer questions about survival and local recurrence, as well as questions about adverse events (AEs), morbidity data, and health-related quali... Read More
Gender:
ALL
Ages:
All
Trial Updated:
03/19/2024
Locations: University of California, Los Angeles, California
Conditions: Spinal Column Tumor
Kaiser Permanente Evaluating Nutritional Interventions in Food-Insecure High-Risk Adults Study
Recruiting
The goal of this randomized controlled trial is to compare the effect of receiving 6 months of monetary support for healthy food through a food delivery platform on change in glycosylated hemoglobin (HbA1c) levels among adults with type 2 diabetes mellitus with glycemic control that is above target level. The main study aims are to: 1. To evaluate whether providing monthly financial support for home-delivered healthy food vs. only free food delivery through the Instacart platform reduces glyco... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/18/2024
Locations: Kaiser Permanente Southern California Department of Research & Evaluation, Pasadena, California
Conditions: Diabetes Mellitus, Type 2
Video Images About Decisions for Ethical Outcomes in the Emergency Department (VIDEO-ED)
Recruiting
A randomized controlled trial of a video decision aid in the Emergency Department Setting to improve advance care planning documentation.
Gender:
ALL
Ages:
50 years and above
Trial Updated:
03/18/2024
Locations: UC Davis, Davis, California
Conditions: Emergencies