California is currently home to 5930 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Los Angeles, San Francisco, San Diego and Sacramento. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Evaluate the Safety and Efficacy of ON101 Cream for the Treatment of Chronic Diabetic Foot Ulcers
Recruiting
The primary efficacy endpoint for this study is the proportion of subjects with complete closure of Target Ulcer during the 20-week Treatment Phase, which is assessed by the blinded independent evaluator.
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
07/15/2022
Locations: Oneness Investigational Site, Carlsbad, California
Conditions: Chronic Diabetic Foot Ulcers
The JULI Registry--Hemp and Cannabis Observational Registry
Recruiting
The JuLi Registry seeks to fill some of the gaps associated with the clinical use of CBD (cannabidiol) and other cannabinoid formulations including THC and others. The overarching goal of this Registry is to rapidly advance research and understanding of the use of cannabis and hemp-based formulations, in the clinical community setting, when it is utilized to manage the symptoms of cancer treatment and other underlying health issues. These symptoms include nausea, neuropathy, and sleeplessness an... Read More
Gender:
All
Ages:
21 years and above
Trial Updated:
07/15/2022
Locations: Precision Cancer Specialists, Los Gatos, California
Conditions: Chronic Pain, Appetite Disorders, Neuropathy, Menopausal Syndrome, Anxiety, Sleep Disturbance, Nausea
The Use of Virtual Reality to Reduce Anxiety and Pain in Perioperative Settings
Recruiting
We will investigate whether the use of Virtual Reality (VR) preoperatively and intraoperatively can help treat pain and anxiety, as measured by patient feedback, vital signs trends, and the amounts of anesthetics, pain medications and anxiolytics used during surgical procedures. The VR intervention will be studied during short hand surgeries normally performed using local anesthesia and sedation.
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
07/13/2022
Locations: UCSF Orthopedic Institute, San Francisco, California
Conditions: Perioperative Pain, Perioperative Anxiety
MIP Versus PCNL for Kidney Stone Disease
Recruiting
The decision to use standard percutaneous nephrolithotomy (PCNL) versus mini-percutaneous nephrolithotomy (MIP) has been a subject of much debate in the urological community. The investigators propose a randomized controlled trial to compare the operative outcomes and complications of mini-percutaneous nephrolithotomy (mini-PCNL) versus standard PCNL for renal stones. The results of this study will help guide the decision making regarding these two procedures in the US population and provide fur... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
07/12/2022
Locations: University of California, San Diego, Medical Center, San Diego, California
Conditions: Kidney Stone
Does Preoperative Pain Medication Management Influence Surgical Outcomes in Spinal Fusion
Recruiting
In light of the current opioid epidemic, there is an urgent need to address chronic opioid use prior to surgery before it is exacerbated by postoperative surgical pain. Our central hypothesis is that patients who taper their opioid use prior to surgery will have reduced postoperative opioid and pain medication usage, less postoperative pain, and improved patient reported outcomes relative to patients that do not taper prior to surgery. Our specific aims include: 1. Determine whether reducing pat... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
07/10/2022
Locations: Stanford Hospital and Clinics, Redwood City, California
Conditions: Opioid Use, Spine Fusion
Adenoma Detection Rate in Water and Air Colonoscopy Using Computer-aided System
Recruiting
Water exchange (WE) is an effective insertion method to minimize insertion discomfort and maximize ADR. It is characterized by infusing water to guide insertion in an airless lumen with suctioning of infused water during insertion and almost complete removal of the infused water when cecal intubation is achieved. A modified Delphi review reported water exchange showed the highest overall ADR, ADR in screening cases, and in the right side of the colon compared with water immersion and air (or CO2... Read More
Gender:
All
Ages:
Between 50 years and 80 years
Trial Updated:
07/08/2022
Locations: Sepulveda Ambulatory Care Center, Los Angeles, California
Conditions: Colon Adenoma, Colonoscopy
A Phase II Study in Patients With Moderate to Severe ARDS Due to COVID-19
Recruiting
This is a Phase II multi-center, double-blind, placebo-controlled, randomized study in Patients with moderate to severe lung injury due to COVID-19 or other potential viral and bacterial pathogens.
Gender:
All
Ages:
18 years and above
Trial Updated:
07/07/2022
Locations: Providence Medical Foundation, Fullerton, California
Conditions: Covid19
Examination of Immunosuppression Adjustment Impact on Kidney Function in Liver Transplant
Recruiting
This is a study to help understand how well new combinations of immunosuppressive medications (medications that weaken your immune system to prevent your body from rejecting the transplanted liver) work compared to standard immunosuppressive medications after your liver transplant. Also the study will assess how safe the new combination of immunosuppressive medicines are and if there are any changes in how your kidneys work after taking these medicines.
Gender:
All
Ages:
Between 18 years and 78 years
Trial Updated:
07/06/2022
Locations: UCLA Medical Center, Los Angeles, California
Conditions: Asses Immunosuppression Modulation on Renal Recovery Post LT
Ocular Pathogen and Transcriptome Investigation Using Comprehensive Sequencing
Recruiting
This is a multi-center randomized controlled evaluator-masked trial designed to compare metagenomic deep sequencing (MDS) versus standard of care testing for improvement of outcomes for intraocular infections. Patients with presumed intraocular infections who meet the eligibility criteria will be randomized to receive MDS testing results or not to receive MDS testing results. All patients will receive standard-of-care testing to guide management. Enrolled patients will be followed at week 2, wee... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
07/05/2022
Locations: University of California San Francisco (UCSF), San Francisco, California
Conditions: Uveitis, Infectious Disease
Phase 2 Study of Efficacy and Safety of AK120, in Subjects With Moderate-to-Severe Atopic Dermatitis
Recruiting
This is a phase 2, multi-center, randomized, placebo-controlled, double-blind, parallel-group, dose-ranging study, conducted in subjects with moderate-to-severe atopic dermatitis.
Gender:
All
Ages:
18 years and above
Trial Updated:
07/04/2022
Locations: AkesoBio Investigative Site 2010, Canoga Park, California
Conditions: Atopic Dermatitis
A Study to Monitor Ambulatory Blood Pressure Monitoring in Hypogonadal Men Treated With Nasal Testosterone Gel
Recruiting
The purpose of this study is to assess the change in 24-hour ambulatory blood pressure monitoring (ABPM) between baseline (Day 0) and Day 120 following 4 months of testosterone therapy with Natesto.
Gender:
Male
Ages:
Between 18 years and 80 years
Trial Updated:
07/04/2022
Locations: Valley Clinical Trials, Northridge, California
Conditions: Hypogonadism
Artisan Aphakia Lens for the Correction of Aphakia in Children
Recruiting
The purpose of this study is to determine the safety and effectiveness of the Artisan Aphakia Lens in the treatment of aphakia in children.
Gender:
All
Ages:
Between 2 years and 21 years
Trial Updated:
06/24/2022
Locations: The Vision Center, Los Angeles, California
Conditions: Aphakia