California is currently home to 5954 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Los Angeles, San Francisco, San Diego and Sacramento. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Characterization of Inclusion Body Myopathy Associated With Paget's Disease of Bone and Frontotemporal Dementia (IBMPFD)
Recruiting
The investigators are researching families with inherited inclusion body myopathy (IBM) and/or Paget disease of bone (PDB) and/or dementia (FTD) which is also called IBMPFD. IBMPFD is caused by mutations in the VCP gene. Our main goal is to understand how changes in the VCP gene cause the muscle, bone and cognitive problems associated with the disease. The investigators are collecting biological specimen such as blood and urine samples, family and medical histories, questionnaire data of patien... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
04/07/2021
Locations: University of California, Irvine, Irvine, California
Conditions: Inclusion Body Myopathy With Early-onset Paget Disease and Frontotemporal Dementia, Paget Disease of Bone, Frontotemporal Dementia, Myopathy
Biomarker Study of Previously Treated Lyme Disease Volunteers in Comparison to Healthy Volunteers
Recruiting
Non-interventional study evaluating stool and blood samples collected from individuals previously treated with Lyme disease versus healthy volunteers
Gender:
All
Ages:
18 years and above
Trial Updated:
04/06/2021
Locations: Dr. Curtis Scribner, Berkeley, California
Conditions: Lyme Disease
Study of Personalized Cancer Therapy to Determine Response and Toxicity
Recruiting
The purpose of this study is to learn more about personalized cancer therapy including response to treatment and side effects. Information about the tests and treatments a person received, or will receive, for their cancer will be collected from medical records to help the researchers determine whether or not patients respond better when their physicians choose to treat them according to the genetic makeup of their tumor. Optional research tests may be performed on tissue, body cavity fluid, blo... Read More
Gender:
All
Ages:
7 years and above
Trial Updated:
04/01/2021
Locations: UCSD Moores Cancer Center, La Jolla, California
Conditions: Cancer
Optimizing Daily Mindfulness Interventions Using Peer Support to Increase Well-Being in First-Year Students
Recruiting
This project aims to examine the effect of a self-guided, evidence-based, online mindfulness intervention on well-being among first-year undergraduates at the 5 Claremont Colleges (5C's) and graduate students in the community. Additionally, it explores the feasibility and efficacy of peer support (pairs) as an adjunctive treatment component to enhance engagement and treatment effects, including social-connectedness, well- being, academic outcomes, and anxiety. Findings will provide insight into... Read More
Gender:
All
Ages:
Between 18 years and 30 years
Trial Updated:
03/31/2021
Locations: Claremont Graduate University, Claremont, California
Conditions: OMI, OMI+, Control Group
To Evaluate the Efficacy and Safety of Parsaclisib and Ruxolitinib in Participants With Myelofibrosis (LIMBER-313)
Recruiting
The purpose of the study is to compare the efficacy of parsaclisib when combined with ruxolitinb versus placebo combined with ruxolitinib in participants with myelofibrosis.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/24/2021
Locations: CCARE, Fresno, California
Conditions: Myelofibrosis, Primary Myelofibrosis, Post Essential Thrombocythemia Myelofibrosis, Post Polycythemia Vera Myelofibrosis
Evaluating the Impact of Incentives on Clinical Trial Participation
Recruiting
The objective of this study is to investigate the impact of incentives on clinical trial participation. 1) characterize key stakeholders' views on and assessment of incentives, 2) reach consensus among stakeholders on the factors to be considered when choosing incentives and their relative importance, 3) pilot test using vignettes for incentive decision making. We hypothesize that potential study participants make trade-offs regarding the characteristics of a research study when deciding whether... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
03/18/2021
Locations: UC Riverside, Riverside, California
Conditions: Hiv, Aging, Incentives
A Study to Evaluate Safety and PK of Multiple Doses of LT3001 Drug Product and Drug-drug Interaction in Healthy Subjects
Recruiting
This Phase 1 study is planned to establish the clinical safety and pharmacokinetics profile of multiple dose of LT3001 drug product and to investigate drug interactions of LT3001 with potential concomitant medications in healthy subjects.
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
03/17/2021
Locations: Lumosa Phase 1 Unit, Cypress, California
Conditions: Acute Ischemic Stroke
Molecular Autopsy Study
Recruiting
This study seeks to incorporate genetic testing into the postmortem examination of cases of sudden unexplained death.
Gender:
All
Ages:
45 years and below
Trial Updated:
03/16/2021
Locations: Scripps Translational Science Institute, La Jolla, California
Conditions: Sudden Unexplained Death
Glucose Differences Between the Left Arm and Right Arm in Diabetic Patients Using a Continuous Glucose Monitor
Recruiting
Continuous glucose monitoring (CGM) is an emerging field for diabetes management. CGMs are small devices primarily placed on a patient's upper arm that allow providers and patients to individualize therapy by looking at real time glucose levels. While the accuracy of these devices is extensively researched, there are no large-scale studies evaluating the differences between left and right arm glucose readings in the diabetic population. Additionally cinnamon and aloe vera are supplements commonl... Read More
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
03/05/2021
Locations: Manshadi Heart Institute, Inc., Stockton, California
Conditions: Diabetes
The Use of a Sustained Dynamic Compression Intramedullary Nail for Subtalar Arthrodesis
Recruiting
The purpose of this study is to determine the clinical efficacy of a novel dynamic sustained compression intramedullary nail for subtalar (talocalcaneal) arthrodesis.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/03/2021
Locations: University of California, Davis Medical Center, Sacramento, California
Conditions: Foot Arthritis
Study of External Neuromodulation to Improve Signs and Symptoms of Dry Eye in Visual Display Terminal Users
Recruiting
Two study arms - sham and treatment; There will be a cross over of the sham group to the treatment group at day 15.
Gender:
All
Ages:
Between 18 years and 69 years
Trial Updated:
02/17/2021
Locations: Fishman Vision, Palo Alto, California
Conditions: Visual Display Users With Previously Undiagnosed Dry Eye
Evaluation of the PhageTech Virus BioResistor
Recruiting
To evaluate the effectiveness of the PhageTech Virus BioResistor to detect bladder cancer biomarkers.
Gender:
All
Ages:
18 years and above
Trial Updated:
02/12/2021
Locations: Providence Saint John's Health Center and the Saint John's Cancer Institute, Santa Monica, California
Conditions: Bladder Cancer