California Clinical Trials

A listing of California Clinical Trials actively recruiting patient volunteers.

In California there are several research institutes and hospitals that conduct clinical trials. The University of California Los Angeles (UCLA) has one of the largest medical research institutes in the state and conducts clinical trials not only in Los Angeles but all across California. The larger cities in California, such as Los Angeles, San Francisco, San Diego, San Jose, and Sacramento all have ongoing clinical trials dedicated to a variety of conditions, including both paid and non-paid clinical trials.

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6191 trials found

Study Comparing Trifarotene Cream, 0.005% To AKLIEF ® (Trifarotene 0.005% Cream) In The Treatment Of Acne Vulgaris

NCT05550337

To compare the safety and efficacy of the test (Trifarotene 0.005% cream), placebo (vehicle cream) and reference AKLIEF® (Trifarotene 0.005% cream) treatments to demonstrate clinical equivalence in subjects with acne vulgaris.

Conditions: Acne Vulgaris

CRC Detection Reliable Assessment With Blood

NCT05551052

The CRC DRAW study will assess the sensitivity and specificity of the blood-based, Next-Gen CRC Screening Test for the detection of CRC.

Conditions: Colorectal Cancer, Adenomas Colon, Colon Cancer, Rectal Cancer, Colon Neoplasm, Colon Lesion, Colon Disease, Colon Polyp, Polyps, Adenoma, Rectal Diseases, Rectal Polyp, Gastrointestinal Neoplasms, Intestinal Neoplasms, Colonic Diseases, Functional, Intestinal Disease

Study of Inebilizumab in Pediatric Subjects With Neuromyelitis Optica Spectrum Disorder

NCT05549258

A Phase 2, open-label, multicenter study to evaluate the pharmacokinetics (PK), pharmacodynamics (PD), and safety of inebilizumab in eligible pediatric participants 2 to < 18 years of age with recently active neuromyelitis optica spectrum disorder (NMOSD) who are seropositive for autoantibodies against aquaporin-4 (AQP4-immunoglobulin [Ig]G).

Conditions: Neuromyelitis Optica Spectrum Disorder

Researchers at UC San Diego Are Learning About the Benefits of Human Milk and How it Influences Infant and Child Health

NCT05553743

The purpose of the UCSD Human Milk Biorepository is to establish and maintain a repository of breast milk samples that can be used to learn more about how breast milk influences infant and child health.

Conditions: Breastfeeding, COVID-19 Infection, COVID-19 Vaccine, Remdesivir, Antibiotics

COVID-19 iCura SARS-CoV-2 Ag OTC: Clinical Evaluation

NCT05555030

SARS-CoV-2 rapid antigen over the counter clinical performance evaluation.

Conditions: SARS-CoV-2 Infection, COVID-19
Phase: Not Applicable

Pulse Oximetry Errors in Hospitalized Patients Across Varying Skin Pigmentation

NCT05554510

This is a prospective observational study designed to quantify and understand errors in pulse oximetry in hospitalized patients in relation to their skin pigmentation. It is driven by three recent retrospective studies showing missed diagnosis of hypoxemia in patients across a spectrum of skin pigmentation, defined as blood SaO2 <90% when their pulse oximeter reads 92% or greater.

Conditions: Hypoxemia, Pulse Oximetry, Skin Pigment

International CDKL5 Clinical Research Network

NCT05558371

Pathogenic variants in the Cyclin-dependent kinase like 5 (CDKL5) gene cause CDKL5 deficiency disorder (CDD, MIM 300672, 105830), a severe developmental and epileptic encephalopathy associated with cognitive and motor impairments and cortical visual impairment. While capability for disease modifying therapies is accelerating, there is a critical barrier for clinical trial readiness that may result in failure of these therapies, not due to lack of efficacy but due to lack of validated outcome mea ...

Conditions: CDKL5, CDKL5 Deficiency Disorder, CDD

Expression of Stress Markers During Meth Treatment (EXPRESS+)

NCT05558345

This is a non-randomized behavioral trial that aims to investigate whether changes in inflammatory and type I IFN expression coincide with changes in methamphetamine use and viral load over the course of 12 weeks in HIV-positive people assigned male at birth with and without methamphetamine use disorder.

Conditions: Substance-Related Disorders, HIV
Phase: Not Applicable

Effect of Anti-inflammatory (ITIS) Diet in Knee Osteoarthritis

NCT05559463

To study the effect of anti-inflammatory diet on clinical and biological outcomes in patients with knee osteoarthritis

Conditions: Osteoarthritis, Knee
Phase: Not Applicable

Remote Cognitive Assessment for Surgical Patients

NCT05566275

This is a pilot study to evaluate the use of remote cognitive testing to identify patients who may have cognitive vulnerability and may benefit from cognitive care pathways. Participants in this study are asked to complete a smartphone battery of thinking, memory, speech, and motor function tests on their smartphone.

Conditions: Mild Cognitive Impairment, Delirium

A Study of mRNA-1010 Seasonal Influenza Vaccine in Adults 50 Years Old and Older

NCT05566639

The purpose of this study is to evaluate the safety and efficacy of mRNA-1010 in preventing seasonal influenza in adults 50 years and older.

Conditions: Seasonal Influenza