Texas is currently home to 4871 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Houston, Dallas, San Antonio and Austin. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Evaluation of Daily Disposable Toric Soft Lenses Manufactured With an Alternative Hydration Process
Recruiting
This is a prospective, multi-site, dispensing, randomized, controlled, double-masked, bilateral wear, 2x2 crossover study to evaluate the safety and effectiveness of the test lens.
Gender:
ALL
Ages:
Between 18 years and 39 years
Trial Updated:
05/09/2025
Locations: Tyler Eye Associates, Tyler, Texas
Conditions: Astigmatism
Clinical Performance Evaluation of the Artificial Intelligence (AI)/ Machine Learning (ML) Technologies Utilized by the Origin Medical EXAM ASSISTANT
Recruiting
A multicenter study will be conducted to assess the role of the AI/ML technologies of Origin Medical EXAM ASSISTANT (OMEA) in interpreting first-trimester fetal ultrasound examinations (11 weeks 0 days - 13 weeks 6 days). The performance of the AI-based system will be compared against the ground truth provided by an independent reading panel of maternal-fetal medicine physicians.
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
05/09/2025
Locations: Total Womens Care PLLC, Houston, Texas
Conditions: To Validate the Clinical Performance of AI/ML Technologies in First-trimester Pregnant Participants, First Trimester Pregnancy
Optimizing Body Mass Index (BMI) With TCMCB07, The Paradox Trial
Recruiting
This is a randomized, double-blind, placebo-controlled study of B07, administered daily by subcutaneous (SC) injection, in up to 100 patients with newly diagnosed metastatic colorectal cancer. This study will evaluate different doses of B07 on weight, body composition and BMI in patients with sub-optimal BMIs (18 to ≤ 29 kg/m2). Treatment will begin on the same day as the start of cancer chemotherapy and continue during the first 28 days of cytotoxic therapy with a goal of preserving muscle and... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/09/2025
Locations: Investigative Site, Laredo, Texas
Conditions: Cachexia; Cancer
53-Week Study Evaluating the Safety and Efficacy of Intra-articular Injections of TPX-100 With Mild to Severe Tibio-Femoral Osteoarthritis of the Knee
Recruiting
53-Week Study Evaluating the Safety and Efficacy of Intra-articular (IA) Injections of TPX-100 vs Placebo in Subjects with Mild to Severe Tibio-Femoral Osteoarthritis of the Knee
Gender:
ALL
Ages:
Between 50 years and 80 years
Trial Updated:
05/09/2025
Locations: Accurate Clinical Research, LLC, Baytown, Texas
Conditions: Osteoarthritis (OA) of the Knee
Study of Novel Treatment Combination Therapies in Participants With Head and Neck Squamous Cell Carcinoma.
Recruiting
Master protocol: The main goal of this master clinical study is to evaluate the efficacy and safety of multiple novel combination therapies in participants with head and neck squamous cell carcinoma (HNSCC) in various substudies.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/09/2025
Locations: The University of Texas, MD Anderson Cancer Center, Houston, Texas
Conditions: Head and Neck Squamous Cell Carcinoma
Post-Cardiac Surgery Acute Kidney Injury Prevention by Administration of Proton Pump Inhibitor (P2 Trial)
Recruiting
The central hypothesis of this research study is that perioperative administration of the proton pump inhibitor (PPI) pantoprazole could reduce the development of acute kidney injury (AKI) following cardiac surgery by activation molecular pathways for kidney protection. The investigators propose a single-center, randomized, controlled, single-blinded trial to determine whether perioperative intravenous administration of pantoprazole will reduce the incidence of AKI, some molecules that can be de... Read More
Gender:
ALL
Ages:
Between 18 years and 90 years
Trial Updated:
05/09/2025
Locations: Memorial Hermann Texas Medical Center, Houston, Texas
Conditions: Acute Kidney Injury
Mirikizumab Real World Protocol
Recruiting
The goal of this observational study is to learn about how effective mirikizumab (Omvoh) is when treating patients with ulcerative colitis (UC) Does mirikizumab (Omvoh) lead to a reduction in symptoms at intervals throughout one year? Participants being prescribed mirikizumab (Omvoh) as part of their regular medical care for UC will answer online survey questions about their bowel habits for 1 year.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/09/2025
Locations: Southern Star Research Institute, San Antonio, Texas
Conditions: Ulcerative Colitis
APVO436 Phase 1b/2 Study in Patients With Newly Diagnosed AML
Recruiting
A multi-center, open-label, dose-finding study of five dose levels of APVO436 in combination with venetoclax and azacitidine (ven/aza) in adult patients with newly diagnosed, CD123+ AML.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/09/2025
Locations: University of Texas Southwestern Medical Center, Dallas, Texas
Conditions: Acute Myeloid Leukemia (AML)
Evaluating Mechanical Properties of Post-Mastectomy Skin Flaps to Estimate Reconstruction Risks, the EMPOWER Study
Recruiting
This study evaluates the skin and surrounding soft tissue that is removed during an implant reconstruction after a mastectomy.
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
05/09/2025
Locations: M D Anderson Cancer Center, Houston, Texas
Conditions: Breast Carcinoma
Phase 1 Dose Escalation and Dose Expansion Trial of NP-101 in Patients With Solid Tumors
Recruiting
To evaluate the safety and preliminary efficacy of NP-101 in patients with solid tumors.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/09/2025
Locations: MD Anderson Cancer Center, Houston, Texas
Conditions: Solid Tumor
A Comparison of NeuroSpan Bridge, NeuraGen Nerve Guide, and Nerve Autograft for Peripheral Nerve Repair
Recruiting
This is a multicenter, prospective, randomized, subject and evaluator blinded clinical trial to asses the efficacy of Auxilium's NeuroSpan Bridge.
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
05/09/2025
Locations: The San Antonio Orthopaedic Group (TSAOG Orthopaedics), San Antonio, Texas
Conditions: Peripheral Nerve Injuries
Validating Innovative Biosensors for Rett Autonomic Symptom Tracking
Recruiting
The VIBRANT study aims to validate biosensors to objectively and directly measure symptoms in Rett syndrome and create confidence in the use of these devices in clinical trials. VIBRANT will use several FDA-cleared wearable biosensors and a non-wearable device to collect symptom data from patients with Rett syndrome for up to 9 weeks. Symptoms of interest include heart rate, breathing, sleep, blood oxygen levels, and movement. Participants will use the biosensors intermittently at home, document... Read More
Gender:
ALL
Ages:
All
Trial Updated:
05/09/2025
Locations: Baylor College of Medicine, Houston, Texas
Conditions: Rett Syndrome