Texas is currently home to 4881 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Houston, Dallas, San Antonio and Austin. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Evaluating the Effects of Tasimelteon vs. Placebo in Treating Pediatric Insomnia
Recruiting
This is a multicenter, double-blind, randomized study to evaluate the efficacy and safety of a daily single oral dose of tasimelteon and matching placebo in male and female pediatric participants with insomnia disorder.
Gender:
ALL
Ages:
Between 2 years and 17 years
Trial Updated:
04/23/2025
Locations: Vanda Investigational Site, San Antonio, Texas
Conditions: Insomnia Disorder
ADAPTING AND ASSESSING THE FEASIBILITY OF A TELEHEALTH DIABETES PREVENTION PROGRAM FOR HISPANIC ADOLESCENTS
Recruiting
Hispanic adolescents are disproportionately burdened by type 2 diabetes (T2D). Social determinants of health (SDoH) serve as barriers to behavior change and participation in disease prevention efforts, especially among vulnerable adolescents. Telehealth is a potentially effective approach for delivering disease prevention programs as it addresses some SDoH like transportation, childcare needs, and parent work schedules. Unfortunately, there are no theory- or evidence-based telehealth diabetes pr... Read More
Gender:
ALL
Ages:
Between 14 years and 16 years
Trial Updated:
04/23/2025
Locations: USDA/ARS Children's Nutrition Research Center, Baylor College of Medicine, Houston, Texas
Conditions: Obesity and Type 2 Diabetes
A Clinical Study to Evaluate the Safety and Efficacy of the FloStent in Men With Benign Prostatic Hyperplasia Symptoms
Recruiting
The goal of this study is to determine the safety and effectiveness of the FloStent, a medical device used to treat men with symptoms of Benign Prostatic Hyperplasia, compared to sham (procedure without deployment of the FloStent). All participants will undergo a flexible cystoscopy and those randomized to the treatment arm will receive the FloStent, while those randomized to the sham arm will not receive the FloStent.
Gender:
MALE
Ages:
45 years and above
Trial Updated:
04/23/2025
Locations: Midtown Urology Associates, Austin, Texas
Conditions: Benign Prostatic Hyperplasia
Study Assessing Left Ventricular Administration of a Genetic Medicine Directing Organ Regeneration in Heart Failure
Recruiting
This clinical trial investigates the safety and preliminary effectiveness of YAP101, a gene therapy designed to improve heart function in adults with ischemic heart failure and reduced ejection fraction (HFrEF). Ischemic heart failure, often resulting from a prior heart attack, leads to poor heart function and quality of life. Current treatments are limited, and there is an urgent need for new therapies. YAP101 works by delivering a gene therapy using a specialized vector to heart cells, target... Read More
Gender:
ALL
Ages:
Between 18 years and 79 years
Trial Updated:
04/23/2025
Locations: Texas Heart Institute, Houston, Texas
Conditions: Heart Failure With Reduced Ejection Fraction
Pilot Trial of Spiritual Care Interventions for Patients With Cancer
Recruiting
This is a pilot trial of the effects of spiritual care interventions on spiritual well-being and readiness to engage in advance care planning (ACP) among black patients with advanced cancer recruited from outpatient settings to determine the feasibility of conducting a larger trial of effects of early integration of spiritual care into outpatient oncology care on patient outcomes.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/23/2025
Locations: The University of Texas Medical Branch, Galveston, Galveston, Texas
Conditions: Advanced Cancer
A Multicenter Phase 1b/2 Study of Adagrasib, Cetuximab, and Cemiplimab for Metastatic Colorectal Cancer Harboring KRAS G12C Mutations
Recruiting
To learn if the drug combination of adagrasib, cetuximab, and cemiplimab can help to control metastatic CRC with KRAS G12C mutations.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/23/2025
Locations: MD Anderson Cancer Center, Houston, Texas
Conditions: Metastatic Colorectal Cancer, KRAS G12C Mutations
A Phase I Study of Decitabine, Lisaftoclax, and Olverembatinib in Patients With Advanced Chronic Myeloid Leukemia and Philadelphia Chromosome-Positive Acute Myeloid Leukemia
Recruiting
To find the recommended doses of lisaftoclax and olverembatinib that can be given in combination with decitabine to participants with advanced CML and Ph+ AML.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/23/2025
Locations: MD Anderson Cancer Center, Houston, Texas
Conditions: Advanced Chronic Myeloid Leukemia, Philadelphia Chromosome-Positive Acute Myeloid Leukemia
A Study Evaluating AMG 193 in Combination With Other Therapies in Participants With Advanced Gastrointestinal, Biliary Tract, or Pancreatic Cancers With Homozygous Methylthioadenosine Phosphorylase (MTAP)-Deletion
Recruiting
The study aims to determine maximum tolerated dose (MTD) or recommended combination dose of the MTA-cooperative PRMT5 inhibitor AMG 193 administered in combination with other therapies in adult participants with metastatic or locally advanced methylthioadenosine phosphorylase (MTAP)-deleted gastrointestinal, biliary tract, or pancreatic cancers. The study also aims to determine the safety profile of AMG 193 administered in combination with other therapies in adult participants with metastatic or... Read More
Gender:
ALL
Ages:
Between 18 years and 100 years
Trial Updated:
04/23/2025
Locations: Oncology Consultants Cancer Center, Houston, Texas
Conditions: Advanced Gastrointestinal, Biliary Tract, and Pancreatic Cancers
A Study Evaluating the Safety and Efficacy of Inhaled AP01 in Participants With Progressive Pulmonary Fibrosis
Recruiting
A randomized, double-blind, placebo-controlled clinical study to evaluate the safety and efficacy of 2 doses of inhaled pirfenidone (AP01) versus placebo on top of standard of care in participants with PPF over 52 weeks.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/23/2025
Locations: Baylor Scott & White Research Institute, Baylor University Medical Center, Dallas, Texas
Conditions: Progressive Pulmonary Fibrosis
Efficacy of LoDoCo in Improving Exercise Capacity Among Patients With HFpEF and Inflammation
Recruiting
The purpose of this research study is to determine the effectiveness of low dose colchicine (LoDoCo) on measures of exercise capacity, physical function, frailty, and quality of life, among patients with heart failure with chronic stable preserved ejection fraction (HFpEF) and systemic inflammation. The use of LoDoCo in this study is considered investigational as it has not been approved by the Food and Drug Administration (FDA) for the treatment of exercise capacity in patients with HFpEF. Par... Read More
Gender:
ALL
Ages:
50 years and above
Trial Updated:
04/23/2025
Locations: UT Southwestern Medical Center, Dallas, Texas
Conditions: Heart Failure, Inflammation
Phase 2 Trial of Obinutuzumab and CC-99282 for Patients With Previously Untreated High Tumor Burden Follicular Lymphoma
Recruiting
To learn if obinutuzumab in combination with CC-99282 can help to control previously untreated, high tumor burden FL
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/23/2025
Locations: M D Anderson Cancer Center, Houston, Texas
Conditions: Follicular Lymphoma, Tumor
Safety and Efficacy of OBX-115 in Advanced Solid Tumors
Recruiting
This is a study to investigate the safety and efficacy of an investigational OBX-115 regimen in adult participants with advanced solid tumors.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/23/2025
Locations: M.D. Anderson Cancer Center (Melanoma/NSCLC), Houston, Texas
Conditions: Tumor Skin, Metastatic Melanoma, Melanoma, Lung Cancer, Metastatic Lung Cancer, Non Small Cell Lung Cancer, Metastatic Non Small Cell Lung Cancer