Texas is currently home to 4891 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Houston, Dallas, San Antonio and Austin. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Electrocorticography in Mapping Functional Brain Areas During Surgery in Patients With Brain Tumors
Recruiting
This pilot clinical trial studies how well electrocorticography works in mapping functional brain areas during surgery in patients with brain tumors. Using a larger than the standard mapping grid currently used during brain tumor surgery or a high-definition grid for electrocorticogram brain mapping may help doctors to better identify which areas of the brain are active during specific limb movement and speech during surgery in patients with brain tumors.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/21/2025
Locations: M D Anderson Cancer Center, Houston, Texas
Conditions: Brain Neoplasm, Metastatic Malignant Neoplasm in the Brain, Recurrent Brain Neoplasm
LCH-IV, International Collaborative Treatment Protocol for Children and Adolescents With Langerhans Cell Histiocytosis
Recruiting
The LCH-IV is an international, multicenter, prospective clinical study for pediatric Langerhans Cell Histiocytosis LCH (age \< 18 years).
Gender:
ALL
Ages:
18 years and below
Trial Updated:
05/21/2025
Locations: Children's Medical Center Dallas, UT Southwestern, Dallas, Texas
Conditions: Langerhans Cell Histiocytosis
Assessing CSF Flow Dynamics in Pediatric Hemorrhagic Hydrocephalus
Recruiting
The purpose of this study is to evaluate the safety and efficacy of ventricular microdosing of indocyanine green (ICG) in order to assess cerebrospinal fluid (CSF) ventricular dynamics and extracranial CSF outflow using fluorescent Cap-based Transcranial Optical Tomography (fCTOT) and Near-InfraRed Fluorescent (NIRF) imaging and to evaluate inflammation markers of the CSF and to correlate with CSF ventricular dynamics, extracranial outflow into the lymphatics, ventriculomegaly, and patient's cli... Read More
Gender:
ALL
Ages:
6 months and below
Trial Updated:
05/20/2025
Locations: The University of Texas Health Science Center at Houston, Houston, Texas
Conditions: Post-hemorrhagic Hydrocephalus (PHH)
Clinical and Biochemical Effects of a Defined Plant-Based Diet on Heart Disease
Recruiting
A plant-based diet will be utilized in the treatment of coronary artery disease.
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
05/20/2025
Locations: Montgomery Heart & Wellness Center, Houston, Texas
Conditions: Coronary Artery Disease
Evaluation of Efficacy and Safety of Milsaperidone as Adjunctive Therapy in Patients With Major Depressive Disorder
Recruiting
The purpose of this study is to determine the efficacy and safety of milsaperidone compared to placebo as adjunctive therapy in patients with Major Depressive Disorder
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
05/20/2025
Locations: Vanda Investigational Site, Richardson, Texas
Conditions: Major Depressive Disorder (MDD)
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of ASC30 Injection in Participants With Obesity
Recruiting
This randomized, double-blind, placebo-controlled single ascending dose (SAD)/ multiple ascending dose (MAD) study is designed to evaluate the safety, tolerability, pharmacokinetics, and efficacy of ASC30 injection
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
05/20/2025
Locations: Ascletis clinical site, San Antonio, Texas
Conditions: Chronic Weight Management
The Use of Cytomegalovirus Cell Mediated Immunity to Optimize the Duration of Letermovir Prophylaxis in Hematopoietic Cell Transplant Recipients
Recruiting
The goal of this laboratory research study is to learn if interrupting a patient's letermovir dosing based on their immune system response can help HSC transplant patients avoid post-treatment CMV infections better than taking letermovir every day without interruption.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/20/2025
Locations: The University of Texas MD Anderson Cancer Center, Houston, Texas
Conditions: Cytomegalovirus Cell Mediated Immunity, Hematopoietic Cell Transplant
Study on Biomarkers of Periodontitis and Type 2 Diabetes Mellitus in Males and Females 30 - 70 Years of Age
Recruiting
The purpose of this study is to learn about the interactions of markers of type 2 diabetes (T2DM) and periodontitis (PD). Study VPE00001 is a multi-center cross-sectional study. Participants will be categorized based on point-of-care hemoglobin A1c (HbA1c) and periodontal disease (PD) staging into 9 subgroups. The key objectives of the study are: * To evaluate immune signatures in well-characterized populations with or without PD and/or T2DM * To evaluate baseline clinical biomarkers of T2DM an... Read More
Gender:
ALL
Ages:
Between 30 years and 70 years
Trial Updated:
05/20/2025
Locations: UT Health Houston School of Dentistry- Site Number : 8400003, Houston, Texas
Conditions: Periodontal Disease
Safety/Efficacy Study of CID-078 in Patients With Advanced Solid Tumor Malignancies
Recruiting
This is a first-in-human, multicenter, open-label, phase 1 study to evaluate safety, tolerability, and efficacy of CID-078, a Cyclin A/B-RxL inhibitor, in patients with advanced solid tumors.
Gender:
ALL
Ages:
12 years and above
Trial Updated:
05/20/2025
Locations: MD Anderson Cancer Center, Houston, Texas
Conditions: Advanced Solid Tumor, Metastatic Solid Tumor, Refractory Solid Tumor, Cancer, Lung Cancer, Triple Negative Breast Cancer, Breast Neoplasms, Neuroendocrine Tumors, Neuroendocrine Carcinoma, RB1 Gene Mutation
Ziftomenib in Combination With Chemotherapy for Children With Relapsed/Refractory Acute Leukemia
Recruiting
The primary objective of the study is to determine the recommended phase 2 dose (RP2D) of ziftomenib in combination with chemotherapy (FLA) in children with relapsed or refractory KMT2A-r, NUP98-r, or NPM1-m acute leukemia based on safety and pharmacokinetics (PK).
Gender:
ALL
Ages:
Between 0 years and 21 years
Trial Updated:
05/20/2025
Locations: Texas Children's Hospital, Houston, Texas
Conditions: Relapsed/Refractory KMT2A-r Acute Leukemia, Relapsed/Refractory NUP98-r Acute Leukemia, Relapsed/Refractory NPM1-m Acute Leukemia
STRICT - Surveillance With TRoponin During Immune Checkpoint Therapy
Recruiting
To learn if monitoring blood levels of heart injury (troponin levels) in cancer participants treated with immune checkpoint inhibitors will lead to decreased heart-related side effects.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/20/2025
Locations: MD Anderson Cancer Center, Houston, Texas
Conditions: Immune Checkpoint Therapy
Bacteriophage Therapy TP-102 in Patients With Diabetic Foot Infection
Recruiting
TP-102 is a novel bacteriophage cocktail comprised of 5 (five) lytic bacteriophages against Staphylococcus aureus, Pseudomonas aeruginosa, and Acinetobacter baumannii. TP-102 is being developed for topical treatment of patients with wound infections including chronic ulcers; applied every other day (three times weekly (TIW)).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/20/2025
Locations: Tranquil Clinical Research, Webster, Texas
Conditions: Diabetic Foot Infection