Texas is currently home to 4891 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Houston, Dallas, San Antonio and Austin. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Triathlon All-Polyethylene Tibia Outcomes Study
NCT04636190
Recruiting
The purpose of this study is to evaluate the clinical functional results of the Triathlon All-Polyethylene Tibia Knee Device.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/06/2025
Locations: Musculoskeletal Institute, University of Texas Health Austin, Austin, Texas
Conditions: Arthropathy of Knee, Replacement, Knee Arthritis
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Project Talk Trial: Engaging Underserved Communities in End-of-life Conversations
NCT04612738
Recruiting
Compared to the general population, individuals from underserved communities are more likely to receive low quality end-of-life care and unwanted, costly and burdensome treatments due in part to a lack of advance care planning (ACP; the process of discussing wishes for end-of-life care with loved ones/clinicians and documenting them in advance directives). This study will use existing, trusted, and respected social networks to evaluate two conversation-based tools intended to engage underserved... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/06/2025
Locations: Turner Alumni Association, Carthage, Texas
Conditions: Advance Care Planning, Advance Directives, Terminal Illness, Chronic Illness, Communication
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A Novel Multiplex ELISA Assay for Evaluating Patients With Gross Hematuria for Bladder Cancer
NCT03193528
Recruiting
To improve upon the non-invasive detection of BCa by further validating a multiplex ELISA assay directed at a BCa-associated diagnostic signature in voided urine samples of patients with gross hematuria.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/06/2025
Locations: UT Southwestern Medical Center at Dallas, Dallas, Texas
Conditions: Bladder Cancer
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Radiation Therapy With Protons or Photons in Treating Patients With Liver Cancer
NCT03186898
Recruiting
This phase III trial studies how well radiation therapy with protons works compared with photons in treating patients with liver cancer. Radiation therapy, such as photon therapy, uses high energy x-rays to send the radiation inside the body to the tumor while proton therapy uses a beam of proton particles. Proton therapy can stop shortly after penetrating through the tumor and may cause less damage to the surrounding healthy organs and result in better survival in patients with liver cancer.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/06/2025
Locations: M D Anderson Cancer Center, Houston, Texas
Conditions: Recurrent Hepatocellular Carcinoma, Stage III Hepatocellular Carcinoma AJCC v7, Unresectable Hepatocellular Carcinoma
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Molecular Basis for Variations in Hereditary Colorectal Cancer Syndromes
NCT02863172
Recruiting
Objectives: 1. To examine the variations in clinical features, survival outcomes, family history, and health behavior among proband patients who are known or suspected to have a hereditary colorectal cancer syndrome 2. To compare the clinical features, survival outcomes, and health behavior of the proband vs. his/her family members who may or may not be affected by the hereditary colorectal cancer syndrome 3. To explore for correlations between germline genetic variations in both the probands a... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/06/2025
Locations: University of Texas MD Anderson Cancer Center, Houston, Texas
Conditions: Hereditary Colorectal Cancer Syndrome
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Optimized Cord Blood Transplantation for the Treatment of Patients With High-risk Hematologic Malignancies Who Have Relapsed After First Allogeneic Stem Cell Transplantation
NCT06807606
Recruiting
The goal of this clinical research study is to learn if intermediate-intensity conditioning therapy followed by a cord blood transplant can help to control high-risk hematological malignancies in patients who need a second allogeneic stem cell transplantation.
Gender:
ALL
Ages:
60 years and below
Trial Updated:
05/05/2025
Locations: The University of Texas M. D. Anderson Cancer Center, Houston, Texas
Conditions: Hematologic Malignancies
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A Phase 2 Trial to Assess Safety and Efficacy of Tofacitinib 2% Cream in the Treatment of Cutaneous T-cell Lymphoma (CTCL), Stages IA, IB, and IIA
NCT06698822
Recruiting
To study the safety and effectiveness of tofacitinib 2% cream in treating early-stage CTCL.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/05/2025
Locations: MD Anderson Cancer Center, Houston, Texas
Conditions: Cutaneous T-Cell Lymphoma
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A Study to Investigate the Safety and Efficacy of KQB198 as Monotherapy and in Combination in Participants With Advanced Hematologic Malignancies
NCT06645886
Recruiting
The goal of this clinical trial is to learn if KQB198 works to treat advanced hematologic malignancies in adults. It will also learn about the safety of KQB198. The main questions it aims to answer are: * What is the safe dose of KQB198 by itself or in combination with other anti-cancer drugs? * Does KQB198 alone or in combination with other anti-cancer drugs decrease the size of the tumor? * What happens to KQB198 in the body? Participants will: * Take KQB198 daily, alone or in combination w... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/05/2025
Locations: Texas Oncology Austin Central, Austin, Texas
Conditions: Hematologic Malignancies, Adult
Register for Updates
Protein Supplementation After ACL Surgery
NCT06311058
Recruiting
The purpose of the study is to assess the longitudinal post-operative care effects of protein supplementation on muscle atrophy in the post-operative period following ACL reconstruction. The main outcome will be muscle size/mass as measured using dual energy x-ray absorptiometry (DEXA) scanning. The primary objective is to assess for any beneficial impact of protein supplementation, with implications of standardizing a recommended protocol for protein supplementation after ACL reconstruction. S... Read More
Gender:
ALL
Ages:
Between 16 years and 40 years
Trial Updated:
05/05/2025
Locations: Houston Methodist, Houston, Texas
Conditions: ACL Reconstruction
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CHARGE Study: CHoice ARchitecture Genetic tEsting
NCT06284330
Recruiting
CHARGE is a hybrid type I feasibility study to compare a choice architecture intervention for cascade genetic testing to usual care.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/05/2025
Locations: UT Southwestern Medical Center, Dallas, Texas
Conditions: Hereditary Cancer
Register for Updates
Effect of BFR Rehab After Achilles Tendon Rupture
NCT06254794
Recruiting
The purpose of this study is to determine if blood flow restriction therapy after Achilles tendon rupture reconstruction decreases post-operative calf atrophy, improves reported outcomes, and ultimately decreases return to play time.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/05/2025
Locations: Houston Methodist Hospital, Houston, Texas
Conditions: Achilles Tendon Rupture
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A Pilot Study for Pupillary Assessment to Predict CAR-T Related Neurotoxicity
NCT06144151
Recruiting
To learn about the relationship between changes in pupil size and reactivity and the start of neurological side effects in patients after receiving CAR-T cell therapy.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/05/2025
Locations: MD Anderson Cancer Center, Houston, Texas
Conditions: Neurotoxicity
Register for Updates