Texas is currently home to 4885 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Houston, Dallas, San Antonio and Austin. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
FaCT Trial (Facilitated Cascade Testing Trial)
Recruiting
The purpose of this study is to assess an intervention that incorporates engagement strategies with a medical team navigator, an educational video and accessible genetic testing services to maximize the genetic testing and education of at-risk relatives. In this study, first degree relatives who agree to participate will either receive this intervention or standard of care. The investigators do not know if the facilitated interventional method will be more effective than the standard of care met... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/24/2024
Locations: MD Anderson Cancer Center, Houston, Texas
Conditions: BRCA1 Mutation, BRCA2 Mutation
Non-Invasive Diagnosis of Pediatric Pulmonary Invasive Mold Infections
Recruiting
This study will establish a non-invasive diagnostic approach and evaluate clinical outcomes for children at high-risk for pulmonary invasive fungal infection (PIFI).
Gender:
ALL
Ages:
Between 120 days and 21 years
Trial Updated:
09/24/2024
Locations: Ascension Seton Medical Center, Austin, Texas
Conditions: Pulmonary Invasive Aspergillosis, Pulmonary Invasive Fungal Infections
Guselkumab vs Golimumab in PsA TNF Inadequate Responder Patients
Recruiting
The trial is an open-label randomized study that will examine whether switching to a selective IL23 inhibitor (guselkumab) is more effective than switching to a second TNFi (golimumab) among patients with PsA who have an inadequate response to a TNFi.
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
09/23/2024
Locations: Heritage Rheumatology and Arthritis Care, Colleyville, Texas
Conditions: Psoriatic Arthritis
Phase III Efficacy and Safety Study of Miconazole Oil for Otomycosis
Recruiting
The goal of this clinical trial is to prove the that miconazole oil works well on fungal infections of the ears, by comparing the drug with a placebo. The researcher or the participants will not know if they are getting the drug or the placebo. The researcher will show the participants how to use the drug or placebo. After 14 days of using the drug or placebo, the participants will be examined by the researcher and graded on how well the drug worked on the ear(s) fungal infection. Participants w... Read More
Gender:
ALL
Ages:
All
Trial Updated:
09/23/2024
Locations: Alamo ENT Associates, San Antonio, Texas
Conditions: Otomycosis
M6®-C Artificial Cervical Disc Two-Level IDE Pivotal Study
Recruiting
Prospective, concurrently controlled, multi-center study to evaluate the safety and effectiveness of the Spinal Kinetics M6-C™ artificial cervical disc compared to anterior cervical discectomy and fusion (ACDF) for the treatment of contiguous two-level symptomatic cervical radiculopathy at vertebral levels from C3 to C7 with or without spinal cord compression.
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
09/20/2024
Locations: Ascension Texas Spine and Scoliosis, Austin, Texas
Conditions: Cervical Disc Degenerative Disorder
Sacituzumab Govitecan in Recurrent Glioblastoma
Recruiting
This is an open-label single arm study. All patients will receive the investigational agent.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/20/2024
Locations: Texas Oncology, Dallas, Texas
Conditions: Glioblastoma
Comparison of Surgery and Medicine on the Impact of Diverticulitis (COSMID) Trial
Recruiting
The COSMID (Comparison of Surgery and Medicine on the Impact of Diverticulitis) trial is a pragmatic, patient-level randomized superiority trial of elective colectomy vs. best medical management for patients with quality of life (QoL) limiting diverticular disease. A parallel observational cohort will include those who are disinclined to have their treatment choice randomized, but are willing to contribute information about their outcomes. The goal of the COSMID trial is to answer the question:... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/20/2024
Locations: UT Southwestern Medical Center, Dallas, Texas
Conditions: Diverticulitis
Genetic Analysis of Pheochromocytomas, Paragangliomas and Associated Conditions
Recruiting
Pheochromocytomas and paragangliomas are neural crest-derived tumors of the nervous system that are often inherited and genetically heterogeneous. Genetic screening is recommended for patients and their relatives, and can guide clinical decisions. However, a mutation is not found in all cases. The aims of this proposal are to: 1) to map gene(s) involved in pheochromocytoma, and 2) identify genotype-phenotype correlations in patients with pheochromocytoma/paraganglioma of various genetic origins.
Gender:
ALL
Ages:
All
Trial Updated:
09/20/2024
Locations: University of Texas Health Science Center, San Antonio, Texas
Conditions: Pheochromocytoma, Paraganglioma, Inherited Cancer Syndrome, Associated Conditions, Kidney Neoplasms, Bone Cancer, Thyroid Neoplasms, Other Cancer
Consent for Use of Stored Patient Specimens for Future Testing
Recruiting
The purpose of this study is to obtain informed consent to use stored human biological materials (HBM) (e.g., blood and other tissues) for future studies that may include genetic testing.
Gender:
ALL
Ages:
All
Trial Updated:
09/20/2024
Locations: Dallas VA Medical Center (3752), Dallas, Texas
Conditions: HIV Infections
Safety and Feasibility of Umbilical Cord Wharton's Jelly Allograft Injections for Knee Osteoarthritis
Recruiting
This is a Pilot Study which is randomized, prospective, open label, dose escalation, non-controlled evaluating safety and feasibility of intra-articular Wharton's Jelly (WJ) allograft will be evaluated in patients suffering with knee osteoarthritis. The participants will be randomized to one of three dosing treatment arms that will consist of one intra-articular knee injection containing either low dose, medium dose or high dose WJ allograft tissue.
Gender:
ALL
Ages:
30 years and above
Trial Updated:
09/19/2024
Locations: Dr. Duc (Steve) Le, MD, Cleveland, Texas
Conditions: Osteoarthritis, Knee
Screening Emotions in Adolescents at the Hospital for mTBI
Recruiting
The goal of this observational study is to develop and validate a clinical tool to predict which adolescents aged 11 to less than 18 years of age with mild traumatic brain injury (mTBI) are at an increased risk for developing significant new or worsening mental health conditions. The main aims the study wish to answer are: * Does the adolescent have new or worsening depression or anxiety defined as a change from their previous medical history using self-reported questionnaires at either one or... Read More
Gender:
ALL
Ages:
Between 11 years and 17 years
Trial Updated:
09/19/2024
Locations: University of Texas Southwestern Medical Center, Dallas, Texas
Conditions: Brain Injury Traumatic Mild, Brain Injuries, Brain Injuries, Acute, Head Injury With Intracranial Hemorrhage, Head Injury Trauma, Brain Injury Traumatic Focal With Loss of Consciousness, Skull Fractures, Diffuse Axonal Injury, Intracranial Hemorrhages, Head Injury
Efficacy of M640 in Acute Lumbosacral Musculoskeletal Conditions.
Recruiting
The goal of this clinical trial is to learn if a modification to metaxalone 640 mg can reduce low back and leg pain. The participants will be 18 to 80 years old, healthy with newly occurring back or leg pain. The main question aims to compare a group taking active treatment and a group taking a look-alike substance containing no active treatment. All participants will answer questions on Day 1, before treatment, and on 7-day after treatment, about: * Amount and quality of pain * Interference wi... Read More
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
09/19/2024
Locations: Heritage Rheumatology & Arthritis Care, Colleyville, Texas
Conditions: Sciatica Acute, Lumbar Spinal Stenosis