Texas is currently home to 5016 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Houston, Dallas, San Antonio and Austin. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Bilirubin Neurotoxicity (BN) and Neurodevelopmental Impairment (NDI) in Extremely Preterm (EP) Infants: Avoidable by Reducing the Usual Intravenous Lipid (UL) Administration
NCT04584983
Recruiting
The purpose of this study is to evaluate the effect of usual versus reduced lipid intake on unbound bilirubin levels, brainstem auditory evoked responses, and neurodevelopmental outcome at 2 years in extremely preterm infants.
Gender:
All
Ages:
27 weeks and below
Trial Updated:
08/02/2023
Locations: The University of Texas Health Science Center at Houston, Houston, Texas
Conditions: Bilirubin Encephalopathy
Register for Updates
Pre-diabetes in Subject With Impaired Fasting Glucose (IFG) and Impaired Glucose Tolerance (IGT)
NCT02969798
Recruiting
HYPOTHESIS: Impaired glucose tolerance (IGT) and impaired fasting glucose (IFG) have distinct pathophysiologic etiologies. Therefore, therapeutic interventions designed to correct the specific underlying pathogenic abnormalities in IGT and IFG will be required to optimally prevent the progressive beta cell failure and development of overt type 2 diabetes.
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
08/02/2023
Locations: The University of Texas Health Science Center at San Antonio, San Antonio, Texas
Conditions: Diabetes Mellitus, Type 2, Impaired Glucose Tolerance (IGT), Impaired Fasting Glucose (IFG)
Register for Updates
Outcomes of Pulmonary Valve Replacement With the INSPIRIS (Model 11500A) Valve
NCT05986396
Recruiting
The goal of this retrospective chart review is to contribute to the literature on the mid-term durability and hemodynamics of the INSPIRS Resilia bioprosthesis when implanted in children and young adults.
Gender:
All
Ages:
Between 0 years and 64 years
Trial Updated:
08/01/2023
Locations: Baylor College of Medicine at CHRISTUS Children's, San Antonio, Texas
Conditions: Heart Valve Prosthesis
Register for Updates
Study of NG-350A Plus Pembrolizumab in Metastatic or Advanced Epithelial Tumours (FORTIFY)
NCT05165433
Recruiting
This is a phase 1a/1b, multicentre, open-label, non-randomized study of NG-350A in combination with pembrolizumab in patients with metastatic or advanced epithelial tumours.
Gender:
All
Ages:
18 years and above
Trial Updated:
08/01/2023
Locations: MD Anderson Cancer Center, Houston, Texas
Conditions: Epithelial Tumor, Metastatic Cancer
Register for Updates
Study of RP1 Monotherapy and RP1 in Combination With Nivolumab
NCT03767348
Recruiting
RPL-001-16 is a Phase 1/2, open label, dose escalation and expansion clinical study of RP1 alone and in combination with nivolumab in adult subjects with advanced and/or refractory solid tumors, to determine the maximum tolerated dose (MTD) and recommended Phase 2 dose (RP2D), as well as to evaluate preliminary efficacy.
Gender:
All
Ages:
18 years and above
Trial Updated:
08/01/2023
Locations: The University of Texas MD Anderson Cancer Center, Houston, Texas
Conditions: Cancer, Melanoma (Skin), Mismatch Repair Deficiency, Microsatellite Instability, Non-melanoma Skin Cancer, Cutaneous Melanoma, NSCLC
Register for Updates
Investigator-Initiated Study of Imipramine Hydrochloride and Lomustine in Recurrent Glioblastoma
NCT04863950
Recruiting
This study is designed as a single center, prospective, open label, single-arm therapeutic trial with both surgical and non-surgical cohorts.
Gender:
All
Ages:
All
Trial Updated:
07/31/2023
Locations: Mays Cancer Center, UT Health San Antonio, San Antonio, Texas
Conditions: Glioblastoma
Register for Updates
BFR Therapy for Post-Op Rehab of ACL Reconstruction With Quadriceps Tendon Autograft
NCT04519801
Recruiting
The overall objective of the proposed research is to conduct a prospective, randomized controlled trial to investigate whether the addition of BFR therapy to standard post-operative rehabilitation regimen significantly improves clinical outcomes following anterior cruciate ligament reconstruction (ACLR) standardized with respect to both surgical technique and graft selection. Patients indicated for ACLR will be screened and offered enrollment into this prospective, randomized controlled trial. M... Read More
Gender:
All
Ages:
Between 15 years and 45 years
Trial Updated:
07/31/2023
Locations: Brooke Army Medical Center- Clinical Research Center, San Antonio, Texas
Conditions: ACL Injury
Register for Updates
Radiation Therapy With Protons or Photons in Treating Patients With Liver Cancer
NCT03186898
Recruiting
This phase III trial studies how well radiation therapy with protons works compared with photons in treating patients with liver cancer. Radiation therapy, such as photon therapy, uses high energy x-rays to send the radiation inside the body to the tumor while proton therapy uses a beam of proton particles. Proton therapy can stop shortly after penetrating through the tumor and may cause less damage to the surrounding healthy organs and result in better survival in patients with liver cancer.
Gender:
All
Ages:
18 years and above
Trial Updated:
07/31/2023
Locations: M D Anderson Cancer Center, Houston, Texas
Conditions: Unrectable or Locally Recurrent Hepatocellular Carcinoma
Register for Updates
Gedatolisib Plus Fulvestrant With or Without Palbociclib vs Standard-of-Care for the Treatment of Patients With Advanced or Metastatic HR+/HER2- Breast Cancer (VIKTORIA-1)
NCT05501886
Recruiting
This is a Phase 3, open-label, randomized, clinical trial evaluating the efficacy and safety of gedatolisib plus fulvestrant with or without palbociclib for the treatment of patients with locally advanced or metastatic HR+/HER2- breast cancer following progression on or after CDK4/6 and aromatase inhibitor therapy.
Gender:
All
Ages:
18 years and above
Trial Updated:
07/30/2023
Locations: Texas Oncology - Austin, Austin, Texas
Conditions: Breast Cancer
Register for Updates
Brain Substrates for Cardiovascular Stress Physiology
NCT05298956
Recruiting
Transcranial infrared laser stimulation is a non-invasive neuromodulation technique. The study will examine the effect of transcranial infrared laser stimulation on cardiovascular and metabolic responses to stress.
Gender:
All
Ages:
Between 18 years and 30 years
Trial Updated:
07/28/2023
Locations: Annie T. Ginty, Waco, Texas
Conditions: Stress Reaction
Register for Updates
Open-Label Proof of Concept Study of VP-315 in Basal Cell Carcinoma
NCT05188729
Recruiting
This is a 2-part, open-label, multicenter, dose-escalation, proof-of-concept study with a safety run-in designed to assess the safety, tolerability, MTD, and objective antitumor efficacy of ascending dose strengths of VP-315 when administered intratumorally to adults with biopsy proven basal cell carcinoma (BCC). The study is expected to enroll approximately 80 subjects with a histological diagnosis of BCC in at least 1 eligible target lesion (confirmed by punch or shave biopsy).
Gender:
All
Ages:
18 years and above
Trial Updated:
07/28/2023
Locations: Austin Institute of Clinical Research - Dripping Springs, Dripping Springs, Texas
Conditions: Basal Cell Carcinoma, Skin Cancer, Cancer of the Skin, Basal Cell, Cancer of the Skin, Carcinoma
Register for Updates
The Effects and Safety of 5% Lifitegrast Ophthalmic Solution in Subjects With Dry Eye Disease in Ocular Graft-versus-Host Disease
NCT04792580
Recruiting
The objective of this study is to evaluate the clinical efficacy of 5% lifitegrast ophthalmic solution in subjects with dry eye disease secondary to ocular Graft-versus-Host Disease compared to placebo.
Gender:
All
Ages:
Between 18 years and 85 years
Trial Updated:
07/28/2023
Locations: Richard W Yee, MD PLLC, Bellaire, Texas
Conditions: Graft-versus-host-disease, Ocular Graft-versus-host Disease
Register for Updates