Texas is currently home to 5027 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Houston, Dallas, San Antonio and Austin. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Ultrasound Evaluation for Improving Patient Selection in vNOTES
Recruiting
Vaginal Natural Orifice Transluminal Endoscopic Surgery (vNOTES) is an emerging field in minimally invasive surgery. International consensus-based statement was recently published to help guide the basis for adopting vNOTES into clinical practice, including regarding patient selection. It was agreed that women with potential adhesions are not appropriate candidates for vNOTES approach including women with suspected adhesions due to history of severe pelvic inflammatory disease (PID) or endometri... Read More
Gender:
Female
Ages:
18 years and above
Trial Updated:
05/17/2023
Locations: University of Texas, Houston, Texas
Conditions: Surgery
Metabolic Remodeling in Pulmonary Arterial Hypertension (PAH)
Recruiting
Pulmonary arterial hypertension (PAH) is a progressive disease in which clinically relevant symptoms present a few years after the onset in rise of pulmonary arterial pressure. Increased PA pressure presents an overload on the right ventricle (RV), with RV failure being a common cause of mortality in PAH. Current therapeutic targets help reduce vascular resistance and RV afterload, however, RV dysfunction may continue to progress. Therefore, the reason for RV failure in PAH cannot be contributed... Read More
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
05/17/2023
Locations: UT Southwestern Medical Center, Dallas, Texas
Conditions: Pulmonary Arterial Hypertension
Isatuximab as Upfront Therapy for the Treatment of High Risk AL Amyloidosis
Recruiting
This phase I trial studies the side effects of isatuximab and to see how well it works in treating patients with high risk immunoglobulin light chain amyloidosis (AL amyloidosis). Isatuximab is a monoclonal antibody that may interfere with the ability of tumor cells to grow and spread.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/17/2023
Locations: UT Southwestern, Dallas, Texas
Conditions: AL Amyloidosis
Oesophageal Protection Study: A Multicentre Study.
Recruiting
Atrial fibrillation (AF) is a common debilitating heart rhythm condition that can cause heart failure and negatively impact a patient's outlook in terms of symptoms and disability. It is an irregular fast heart rhythm disorder coming from the top chamber of the heart (left atrium). Catheter ablation treatment has been shown to be effective in controlling or eliminating AF and its associated symptoms. This is now a common and effective treatment option for patients suffering with AF. During ablat... Read More
Gender:
All
Ages:
Between 18 years and 85 years
Trial Updated:
05/17/2023
Locations: Texas Cardiac Arrhythmia Research Foundation, Austin, Texas
Conditions: AF - Atrial Fibrillation, Complication, Atrio-Esophageal Fistula
Safety and Feasibility of Paired Vagus Nerve Stimulation With Rehabilitation for Improving Upper Extremity Function in People With Cervical Spinal Cord Injury
Recruiting
The purpose of this study is to determine the safety and feasibility of pairing vagus nerve stimulation (VNS) with rehabilitation and to determine the efficacy of pairing VNS with rehabilitation.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/16/2023
Locations: The University of Texas Health Science Center at Houston, Houston, Texas
Conditions: Cervical Spinal Cord Injury
Allogeneic NK T-Cells Expressing CD19 Specific CAR in B-Cell Malignancies
Recruiting
This study is a multi-center study to evaluate the safety of KUR-502 in subjects with refractory/relapsed B-cell NHL or leukemia (ALL or CLL).
Gender:
All
Ages:
Between 3 years and 75 years
Trial Updated:
05/16/2023
Locations: Baylor College of Medicine, Houston, Texas
Conditions: NHL, Relapsed, Adult, B-cell Lymphoma, B-cell Leukemia, DLBCL - Diffuse Large B Cell Lymphoma, ALL, Adult B Cell, ALL, Childhood, CLL/SLL
JAB-3312 Based Combination Therapy in Adult Patients With Advanced Solid Tumors
Recruiting
To evaluate the safety and tolerability of JAB-3312 administered in investigational regimens in adult participants with advanced solid tumors.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/16/2023
Locations: Research Site, Houston, Texas
Conditions: Solid Tumor, NSCLC
DECAMP 1 PLUS: Prediction of Lung Cancer Using Noninvasive Biomarkers
Recruiting
DECAMP 1 PLUS aims to improve the efficiency of the diagnostic evaluation of patients with indeterminate pulmonary nodules (8-25 mm). Molecular biomarkers for lung cancer diagnosis measured in minimally invasive and non-invasive biospecimens may be able to distinguish between malignant or benign indeterminate pulmonary nodules in high-risk smokers. Ultimately, this study aims to validate molecular as well as clinical and imaging biomarkers of lung cancer in individuals with indeterminate lung no... Read More
Gender:
All
Ages:
46 years and above
Trial Updated:
05/16/2023
Locations: MD Anderson Cancer Center [Administrative Site], Houston, Texas
Conditions: Pulmonary Disease
Evaluation of Hemostasis in Bleeding and Thrombotic Disorders
Recruiting
The objective of this study will be to assess the coagulation system in-vitro in a variety of bleeding and clotting disorders using the ROTEG analyzer and the thrombin generation assay.
Gender:
All
Ages:
Between 1 day and 98 years
Trial Updated:
05/16/2023
Locations: The Univerisity of Texas Health Science Center at Houston, Houston, Texas
Conditions: Blood Coagulation Disorders, Inherited, Thrombotic Disorder
Study of Immune Globulin Intravenous (Human) GC5107 in Pediatric Subjects With Primary Humoral Immunodeficiency
Recruiting
The purpose of this study is to evaluate the pharmacokinetics and safety of Immune Globulin Intravenous (Human) GC5107 in pediatric subjects with Primary Humoral Immunodeficiency (PHID).
Gender:
All
Ages:
Between 2 years and 16 years
Trial Updated:
05/15/2023
Locations: Allergy Partners of North Texas Research, Dallas, Texas
Conditions: Primary Immune Deficiency
VItamin C in Thermal injuRY: The VICToRY Trial
Recruiting
This study aims to show that giving high dose, intravenous vitamin C in addition to standard care to burned critically ill patients will be associated with less organ dysfunction, improved survival and a quicker rate of recovery. In this study, all patients will receive standard care and of the patients will also receive high dose intravenous vitamin C, while the other half of patients will receive placebo.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/15/2023
Locations: Southwestern Medical Center - University of Texas, Dallas, Texas
Conditions: Shock, Thermal Burn
Yield of Diagnostic Tests and Effects of Crofelemer for Chronic Idiopathic Diarrhea In Non-HIV Patients
Recruiting
The purpose of this study is to evaluate the effectiveness of the drug Crofelemer in the treatment of non-HIV patients with chronic idiopathic diarrhea; to determine the prevalence of identifiable causes of chronic diarrhea in a non-HIV patients; to assess the diagnostic yield, in terms of identification of treatable etiologies, of commercially available diagnostic evaluations in adult, non-HIV patients with chronic idiopathic diarrhea, that is, evaluate which tests, among the standard diagnosti... Read More
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
05/15/2023
Locations: The University of Texas Health Science Center at Houston, Houston, Texas
Conditions: Chronic Diarrhea of Unknown Origin