Texas is currently home to 4879 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Houston, Dallas, San Antonio and Austin. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Promoting Recovery Outcomes Through Precise Early Locomotor Interventions in Persons With Spinal Cord Injury
Recruiting
The purpose of this study is to evaluate if a specific type of additional walking therapy, called body weight supported treadmill training (BWSTT) affects walking ability following a traumatic spinal cord injury. Specifically, the study will look at whether starting BWSTT, which uses a body harness to support body weight while walking on a treadmill at different times within the first 6 months after the injury, makes a difference in how effective this therapy may be, While we know that the brain... Read More
Gender:
ALL
Ages:
Between 16 years and 75 years
Trial Updated:
04/04/2024
Locations: Baylor Scott and White Institute for Rehabilitation, Fort Worth, Texas
Conditions: Spinal Cord Injuries
Healing Osteoarthritic Joints in the Wrist With Adult ADRCs
Recruiting
This is a prospective, randomized, double-blinded, active controlled, single site safety and efficacy study in subjects suffering from chronic wrist osteoarthritis comparing a single ADRC injection generated with the Transpose® RT system into the wrist.
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
04/04/2024
Locations: HD Research, Houston, Texas
Conditions: Osteoarthritis of the Wrist
A Long-term Follow-up Study to Evaluate SKG0106 in the Treatment of Patients With nAMD
Recruiting
This is a Prospective, Non-interventional, Multicenter, Long-term Follow-up Study to Evaluate SKG0106 in the Treatment of Patients with Neovascular (Wet) Age-related Macular Degeneration (nAMD). All subject who completed the parent clinical study (NCT06213038 and NCT05986864) will undergo safety and efficacy assessments up to 5 years post study drug injection.
Gender:
ALL
Ages:
50 years and above
Trial Updated:
04/03/2024
Locations: Retina Consultants of Texas, Katy, Texas
Conditions: Neovascular (Wet) Age-related Macular Degeneration
Nicotinamide Riboside (NR) to Treat Moyamoya-like Cerebrovascular Disease in Smooth Muscle Dysfunction Syndrome (SMDS)
Recruiting
The purpose of this study is to determine whether SMDS patients treated with NR at the proposed dose exhibit decreased glucose uptake in the aorta, to determine if NR treatment results in measurable changes of blood NAD+ and NR levels, to determine if aortic measurements are stable after treatment with NR and to evaluate the safety and tolerability of NR in SMDS patients.
Gender:
ALL
Ages:
Between 5 years and 18 years
Trial Updated:
04/03/2024
Locations: The University of Texas Health Science Center at Houston, Houston, Texas
Conditions: Smooth Muscle Dysfunction Syndrome (SMDS)
Prandial Metabolic Phenotype in Adults
Recruiting
Previous studies suggest that changes in metabolism due to the effects of aging might serve as a potential for therapeutic agents. The investigating lab developed a pulse method combining multiple stable isotopes to study multiple metabolic pathways in the same individual simultaneously. By measuring whole-body metabolism in a large group of older adults, the investigators may be able to unravel age-related deterioration in protein turnover (synthesis and breakdown) that contributes to impaired... Read More
Gender:
ALL
Ages:
Between 60 years and 80 years
Trial Updated:
04/03/2024
Locations: Human Clinical Research Facility, College Station, Texas
Conditions: Protein Metabolism
Family Champions Project
Recruiting
This evaluation uses a formative approach and a descriptive design with repeated measures to assess the efficacy of a Continuous Quality Improvement (CQI) Process to improve services delivered by the Family Champions Project (FCP). The FCP delivers education-based services-TYRO Leadership and Core Communication curricula-with funding from the Office of Family Assistance to low-income fathers and mothers to promote healthy family relationships and economic stability in their households. TYRO Lead... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/03/2024
Locations: Anthem Strong Families, Dallas, Texas
Conditions: Fathers, Mothers
HER2-specific Chimeric Antigen Receptor (CAR) T Cells for Children With Ependymoma
Recruiting
This is a Phase I study to evaluate the safety profile of a type of immune therapy called HER2 CAR T cells (short for HER2 chimeric antigen receptor T cells). In addition to looking for side effects, we will study how well this treatment works against a brain tumor called ependymoma that has come back after treatment (recurrent) or has not responded well to treatment (progressive) in children. The HER2 CAR T cells used in this trial are made from the patient's own blood. A new gene, called the H... Read More
Gender:
ALL
Ages:
Between 1 year and 22 years
Trial Updated:
04/03/2024
Locations: Texas Children's Cancer Center, Houston, Texas
Conditions: Ependymoma
ARGONAUT: Stool and Blood Sample Bank for Cancer Patients
Recruiting
ARGONAUT is a longitudinal, prospective, observational study that will enroll up to 5,000 advanced-stage cancer patients of diverse racial backgrounds to collect data used to develop precision microbiome medicines and for the identification of clinically actionable cancer-specific biomarkers to guide therapeutic decisions. Four types of solid tumor cancers will be profiled including non-small cell lung cancer (NSCLC), triple negative breast cancer (TNBC), colorectal cancer (CRC) and pancreatic c... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/03/2024
Locations: Southwest Family Medicine Associates, Dallas, Texas
Conditions: Non-small Cell Lung Cancer, Colorectal Cancer, Triple Negative Breast Cancer, Pancreas Cancer
Prospective Long-Term Outcomes of a Standardized Ross Procedure
Recruiting
This standardized prospective long-term outcome analysis will help reaffirm these findings via a multicenter patient cohort and describe the best practices/techniques for stabilization of the autograft and right ventricular outflow tract reconstruction.
Gender:
ALL
Ages:
Between 18 years and 90 years
Trial Updated:
04/02/2024
Locations: Baylor Scott and White Heart Hospital, Plano, Texas
Conditions: Ross Procedure (Pulmonary Autograft Replacement)
Activities-based Locomotor Training Program Versus Traditional Physical Therapy in Children With Cerebral Palsy
Recruiting
The purpose of this study is to investigate the impact of an intensive activities-based locomotor training program as compared to traditional physical therapy on activity, participation, and central and peripheral neurophysiological adaptation in children with cerebral palsy.
Gender:
ALL
Ages:
Between 2 years and 6 years
Trial Updated:
04/01/2024
Locations: Baylor University, Waco, Texas
Conditions: Cerebral Palsy
Neoadjuvant Sasanlimab With Radiation as an in Situ Vaccine for Cisplatin-ineligible Muscle Invasive Bladder Cancer
Recruiting
This is a prospective, single-institution, single-arm, phase II clinical trial that tests a novel strategy of neoadjuvant Sasanlimab, an immune checkpoint inhibitor (ICI), in combination with stereotactic body radiation therapy as an in-situ vaccination in patients, who are ineligible to receive cisplatin-based chemotherapy and undergoing radical cystectomy for muscle-invasive bladder cancer.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/31/2024
Locations: Houston Methodist Hospital, Houston, Texas
Conditions: Urothelial Carcinoma Bladder
A Clinical Trial on Safety and Efficacy of CBT-001 in Patients With Pterygium
Recruiting
The objective is to evaluate the safety and efficacy of low dose and high dose CBT-001 eye drop dosed twice daily for 24 months compared to vehicle in reducing conjunctival hyperemia and preventing pterygium progression in eyes with pterygia.
Gender:
ALL
Ages:
12 years and above
Trial Updated:
03/29/2024
Locations: Baylor College of Medicine, Houston, Texas
Conditions: Pterygium