Texas is currently home to 4857 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Houston, Dallas, San Antonio and Austin. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Integrated Tele-Behavioral Activation and Fall Prevention for Low-income Homebound Seniors With Depression
Recruiting
This study will test clinical and cost effectiveness of an integrated tele- and bachelor's-level counselor/coach delivered behavioral activation (BA) and fall prevention (FP) for low-income homebound older adults. The long-term objective of the proposed study is to improve access to depression treatment and fall prevention for growing numbers of low-income homebound seniors. We plan to recruit 320 low-income, racially diverse homebound seniors who are served by a home-delivered meal (HDM) progra... Read More
Gender:
ALL
Ages:
Between 50 years and 100 years
Trial Updated:
01/07/2024
Locations: University of Texas at Austin, Austin, Texas
Conditions: Depression, Unipolar, Fall
Implementation of the Parents Taking Action in Paraguay
Recruiting
The principal aim of this study is to conduct a single group design pilot of a psychoeducational caregiver training (i.e., culturally adapted Parents Taking Action) with a group of family caregivers of young children with autism in Paraguay. The following research questions will be addressed: Research Question #1: What is the feasibility and acceptability of the intervention? Research Question #2: Do participants improve between pre and post-test on outcome measures? Parents will receive 10 wee... Read More
Gender:
ALL
Ages:
Between 18 years and 100 years
Trial Updated:
01/04/2024
Locations: University of Texas at Austin, Austin, Texas
Conditions: Depression, Autism
Coflex PS3 Actual Conditions for Use Study
Recruiting
A 2 and 5 year evaluation of clinical outcomes in the treatment of degenerative spinal stenosis with concomitant low back pain by decompression with additional stabilization using the coflex® Interlaminar Technology for FDA Actual Conditions of Use Study.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/04/2024
Locations: Austin Neurosurgeons, Austin, Texas
Conditions: Spinal Stenosis Lumbar
CLN-049 in Patients With Relapsed/Refractory Acute Myeloid Leukemia (AML) or Myelodysplastic Syndrome (MDS)
Recruiting
CLN-049-001 is a Phase 1, open-label, multicenter, first-in-human trial of CLN-049 in patients with Relapsed/Refractory Acute Myeloid Leukemia (AML) or Myelodysplastic Syndrome (MDS)
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/22/2023
Locations: MD Anderson, Houston, Texas
Conditions: Relapsed/Refractory Acute Myeloid Leukemia (AML), Myelodysplastic Syndrome (MDS)
The Mobility Toolkit: Electronically Augmented Assessment of Functional Recovery Following Lower-extremity Trauma
Recruiting
The study will prospectively enroll and follow 300 participants ages 18-60 surgically treated for a lower-extremity articular injury including fractures of the tibial plateau, pilon, ankle, and calcaneus.
Gender:
ALL
Ages:
Between 18 years and 60 years
Trial Updated:
12/22/2023
Locations: University of Texas Health Science Center - Houston, Houston, Texas
Conditions: Gait
A Study to Evaluate DAY101 in Pediatric and Young Adult Patients With Relapsed or Progressive Low-Grade Glioma and Advance Solid Tumors
Recruiting
FIREFLY-1 is an ongoing, Phase 2, multi center, open-label study to evaluate the safety and efficacy of oral pan-RAF inhibitor DAY101 in pediatric, adolescent, and young adult patients with recurrent or progressive low-grade glioma or an advanced solid tumor harboring a known RAF alteration.
Gender:
ALL
Ages:
Between 6 months and 25 years
Trial Updated:
12/21/2023
Locations: Texas Children's Hospital, Houston, Texas
Conditions: Low-grade Glioma, Advanced Solid Tumor
Safety and Efficacy Study of reSept ASD Occluder for Treating Secundum ASD
Recruiting
Evaluation of the safety and efficacy of the reSept ASD Occluder to treat patients with clinically significant secundum atrial septal defect
Gender:
ALL
Ages:
84 years and below
Trial Updated:
12/21/2023
Locations: Medical City Dallas Hospital, Dallas, Texas
Conditions: Heart Septal Defect, Heart Septal Defects, Atrial, Heart Defects, Congenital, Cardiovascular Abnormalities, Cardiovascular Diseases, Heart Diseases, Congenital Abnormalities
Impact of Atelectasis on RVEDP Following Orthotropic Heart Transplantation
Recruiting
Following orthoptopic heart transplantation (OHT), children undergo surveillance cardiac catheterizations to assess for signs of rejection including muscle biopsy as well as pressure measurements to guide post transplant treatment regiments. These procedures are done under general anesthesia which promotes lung tissue collapse (atelectasis). What is not known is the effect of atelectasis on intracardiac pressures which are a critical area of monitoring post-transplant patients for rejection.
Gender:
ALL
Ages:
All
Trial Updated:
12/20/2023
Locations: Texas Childrens Hospital, Houston, Texas
Conditions: Heart Transplant Failure, Anesthesia
Implementation of Therapy Together
Recruiting
The goal of this pilot clinical trial is to learn about the implementation of Therapy Together, a pediatric constraint-induced movement therapy program in young children with unilateral cerebral palsy. The main question\[s\] it aims to answer are: * Is the Therapy Together program effective in improving hand function and occupational performance compared to usual care? * Is it feasible to implement the Therapy Together program within the standard care, early intervention framework? Participant... Read More
Gender:
ALL
Ages:
Between 3 months and 35 months
Trial Updated:
12/20/2023
Locations: Scottish Rite for Children, Frisco, Texas
Conditions: Cerebral Palsy, Hemiplegic Cerebral Palsy
A Registry of Subjects With Primary Indeterminate Lesions or Choroidal Melanoma
Recruiting
The purpose of this observational research study is to follow participants who have been treated with either bel-sar or received alternate treatment (sham, standard of care therapy, etc.) while participating in a previous Aura Biosciences clinical research study to assess the long-term safety and effectiveness in these subjects. This study will collect information from procedures conducted as part of routine follow-up eye care and cancer care. Additionally, the registry will collect all adverse... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/20/2023
Locations: Texas Retina Associates, Dallas, Texas
Conditions: Choroidal Melanoma, Indeterminate Lesions of Eye
Substance Abuse Pre-Treatment Screening Study
Recruiting
The overarching goal of this project is to have a consolidated consent and evaluation procedure that will lead potential subjects to the most appropriate clinical trial or human laboratory study (and its consent process) for their presenting concerns or interests. A second purpose is to have a consolidated intake data base on which secondary analyses can be conducted.
Gender:
ALL
Ages:
Between 18 years and 60 years
Trial Updated:
12/19/2023
Locations: University of Texas Medical School- Houston, Dept. of Psychiatry Mental Sciences Institute, Houston, Texas
Conditions: Cocaine Abuse, Cocaine Dependence, Opiate Dependence, Alcohol Dependence, Substance Abuse
Open Nipple Sparing Mastectomy (NSM)
Recruiting
This is retrospective, multicenter chart review is to evaluate the complication rates of prophylactic open NSM procedures through 42 days postoperatively
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
12/17/2023
Locations: Univ. of Texas MD Anderson Cancer Center, Houston, Texas
Conditions: Nipple Sparing Mastectomy