Texas is currently home to 4888 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Houston, Dallas, San Antonio and Austin. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
UTHealth Turner Syndrome Research Registry
NCT03185702
Recruiting
The investigators will conduct genetic comparisons between Turner Syndrome (TS) patients with and without Bicuspid Aortic Valve (BAV) to identify causative agents of BAV in people with TS. The investigators will correlate the patterns and prevalence of structural heart defects in TS women with emerging molecular data to identify patients who are at high risk for cardiovascular complications
Gender:
FEMALE
Ages:
All
Trial Updated:
11/27/2023
Locations: University of Texas Health Science Center Houston, Houston, Texas
Conditions: Turner Syndrome
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Pediatric Vasculitis Initiative
NCT02006134
Recruiting
Childhood chronic vasculitis describes a group of rare life-threatening diseases that have in common inflammation of blood vessels in vital organs such as kidneys, lungs and brain. Most knowledge about them comes from adult patients. Severe disease requires aggressive life-saving treatments with steroids and some cancer drugs which can themselves cause damage, and increase risks of cancer and severe infections. Conversely, milder disease can be treated with less toxic drugs. Different classifica... Read More
Gender:
ALL
Ages:
20 years and below
Trial Updated:
11/27/2023
Locations: Texas Children's Hospital, Houston, Texas
Conditions: Wegeners Granulomatosis (Granulomatosis With Polyangiitis), Microscopic Polyangiitis, Polyarteritis Nodosa, Takayasu Arteritis, Primary CNS Vasculitis, Unclassified Vasculitis, Eosinophilic Granulomatosis With Polyangiitis
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Nasal Compression Device Study for Epistaxis
NCT05789264
Recruiting
This study will explore how a nasal compression device compares to manual compression for stopping anterior nosebleeds. This will be a non-randomized controlled trial enrolling participants presenting to medical care for anterior nosebleeds. Participants will be assigned to receive either a nasal compression device or standard of care consisting of digital compression. Participants will be asked to complete survey questions to assess satisfaction with the care they received, comfort, and overall... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/20/2023
Locations: Next Level Urgent Care, Houston, Texas
Conditions: Epistaxis Nosebleed
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Prospective Database Registry Study of Scoliosis in Children With Cerebral Palsy
NCT00680264
Recruiting
The purpose of this study is to determine the radiographic and clinical outcomes of Scoliosis surgical and non-operative treatment in patients with Cerebral Palsy.
Gender:
ALL
Ages:
Between 8 years and 21 years
Trial Updated:
11/20/2023
Locations: Texas Scottish Rite Hospital, Dallas, Texas
Conditions: Cerebral Palsy, Scoliosis
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Appropriateness of Methodist Health System(MHS) Inter-facility Transfers of Traumatic Intracranial Subarachnoid Hemorrhage and Spontaneous Bleeds for Level-1 Advanced Surgical Intervention
NCT06136078
Recruiting
Brain injuries are common and challenging problems faced by emergency physicians. These diagnoses may include traumatic intracerebral hemorrhage, subarachnoid hemorrhage, ruptured cerebral aneurysms, unruptured cerebral aneurysms, and arteriovenous malformations, which require neurological, neurosurgical, and/or endovascular treatment.
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
11/15/2023
Locations: Clinical Research Institute at Methodist Health System, Dallas, Texas
Conditions: Traumatic Intracranial Subarachnoid Hemorrhage
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Penetrating Trauma Registry and Open Source Data
NCT06136273
Recruiting
Penetrating injuries comprise roughly 30% of Methodist Health System (MHS) trauma patients. Firearm-related events have become more prevalent in the past few years. Active shooter events, mass casualties, assaults, and homicide are more commonplace which leads to an increase of trauma patients needing management of penetrating injuries.
Gender:
ALL
Ages:
Between 16 years and 75 years
Trial Updated:
11/14/2023
Locations: Methodist Dallas Medical Center, Dallas, Texas
Conditions: Penetrating Trauma Registry and Open Source Data
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Clinical Outcome of Pericardial Closure Using Gentrix Following Cardiac Surgery
NCT06136182
Recruiting
A descriptive comparative project will be conducted to determine if there is a difference in outcomes for adult patients requiring pericardial reconstruction using CorMatrix compared to Gentrix
Gender:
ALL
Ages:
Between 18 years and 85 years
Trial Updated:
11/14/2023
Locations: Clinical Research Institute at Methodist Health System, Dallas, Texas
Conditions: Clinical Outcome of Pericardial Closure Using Gentrix
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DETEC® Esterase for Screening Wound Infection at Point of Care
NCT04614870
Recruiting
This non-interventional, single-blinded, prospective, observational study assesses the planar distribution of leukocyte esterase in wounds by placing wound exudates soaked wound dressings in the DETEC® Esterase device during routine wound care. The output of the device is correlated with clinical determination of infection to assess the device efficacy in identifying presumptive infections.
Gender:
ALL
Ages:
21 years and above
Trial Updated:
11/14/2023
Locations: Complex Healthcare Solutions, Arlington, Texas
Conditions: Diabetic Foot Ulcer, Venous Leg Ulcer, Pressure Ulcer
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DETEC® pH Point of Care Wound Diagnostic Test
NCT04614038
Recruiting
The purpose of this study is to determine the relationship between wound alkalinity and the non-healing status of chronic ulcer wounds. It is hypothesized that wounds with an alkaline environment as indicated by DETEC pH will have a high chance of not healing over 12 weeks of wound care.
Gender:
ALL
Ages:
21 years and above
Trial Updated:
11/14/2023
Locations: Complex Healthcare Solutions, Arlington, Texas
Conditions: Diabetic Foot Ulcer, Venous Leg Ulcer, Pressure Ulcer, Wound, Non-Healed
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Cardiovascular Events Among Adults Patients With Relapsed or Refractory Aggressive B-Cell Lymphoma Treated With Standard of Care Chimeric Antigen Receptor T Cell Therapy
NCT04870853
Recruiting
This study characterizes cardiac events following standard of care chimeric antigen receptor T cell therapy in patients with aggressive B-Cell Lymphoma that has come back (relapsed) or does not respond to treatment (refractory). The results from this study may allow a description of these events, their managements and outcome.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/10/2023
Locations: M D Anderson Cancer Center, Houston, Texas
Conditions: Recurrent Aggressive B-Cell Non-Hodgkin Lymphoma, Recurrent Diffuse Large B-Cell Lymphoma, Recurrent High Grade B-Cell Lymphoma, Recurrent Primary Mediastinal (Thymic) Large B-Cell Lymphoma, Recurrent Transformed Follicular Lymphoma to Diffuse Large B-Cell Lymphoma, Refractory Aggressive B-Cell Non-Hodgkin Lymphoma, Refractory Diffuse Large B-Cell Lymphoma, Refractory High Grade B-Cell Lymphoma, Refractory Primary Mediastinal (Thymic) Large B-Cell Lymphoma, Refractory Transformed Follicular Lymphoma to Diffuse Large B-Cell Lymphoma
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Comparative Pharmacokinetic Study of Three Abatacept Products in Male Normal Healthy Volunteers by the Subcutaneous Route
NCT06126042
Recruiting
This is a randomised, double-blind, single dose, parallel groups study to compare the PK, immunogenicity, and safety of 3 abatacept products (DRL_AB, RP and RMP) in male NHV.
Gender:
MALE
Ages:
Between 18 years and 50 years
Trial Updated:
11/08/2023
Locations: ICON Early Phase Services, LLC, San Antonio, Texas
Conditions: Rheumatoid Arthritis
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Project Sueño: Sleep & Understanding Early Nutrition in Obesity
NCT06117631
Recruiting
The purpose of the study is to understand how mothers think and feel about feeding their babies and putting them to sleep, understand more about programs that can support mothers taking care of babies, and how professionals can be most helpful in helping mothers make decisions about their baby's feeding and sleeping. The overarching goal is to prevent early life obesity and progression to metabolic syndrome in high-risk populations, starting with healthy toddler weights by age 2 years.
Gender:
FEMALE
Ages:
Between 18 years and 45 years
Trial Updated:
11/01/2023
Locations: CommUnity Care: North Central Health Center, Austin, Texas
Conditions: Infant Overweight, Infant Obesity, Infant Overnutrition, Infant Development, Metabolic Syndrome, Diabetes Mellitus Risk
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