Texas is currently home to 4891 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Houston, Dallas, San Antonio and Austin. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Childhood Trauma, Exercise, and Cognition
NCT05972265
Recruiting
This study aims to identify and compare the effects of acute and chronic exercise interventions on cognition in middle-aged adults with cognitive complaints and a history of abuse or neglect in childhood. Each participant will be enrolled in the study for up to 78 days, in five parts following verification that the participant meets criteria to be included in the study: 1) initial assessment; 2) first acute exercise condition in lab, symptom measures, and neuropsychological testing; 3) second ac... Read More
Gender:
ALL
Ages:
Between 40 years and 60 years
Trial Updated:
11/27/2023
Locations: University of Texas at Austin, Austin, Texas
Conditions: Adverse Childhood Experiences
Register for Updates
Operant Conditioning for Rehabilitation After Stroke
NCT05020080
Recruiting
The purposes of this study include: 1. To test if multiple upper extremity muscles represented within a discrete primary motor cortex site reflect existing muscle synergies after stroke. 2. To test if altered muscle synergies and intermuscular coordination are malleable to motor evoked potential conditioning that induces corticospinal plasticity for the targeted muscle, wrist extensor carpi radialis
Gender:
ALL
Ages:
Between 40 years and 75 years
Trial Updated:
11/27/2023
Locations: University of Houston, Houston, Texas
Conditions: Stroke
Register for Updates
Study of HQP1351 in Subjects With Refractory CML and Ph+ ALL
NCT04260022
Recruiting
A multi-center, open-label, randomized, phase Ib study to evaluate the pharmacokinetics (PK) of HQP1351 and to determine the recommended phase 2 dose (RP2D) of HQP1351 in subjects with CML chronic phase (CP), accelerated phase (AP), or blast phase (BP) or with Ph+ ALL, who have experienced resistance or intolerance to at least two tyrosine kinase inhibitors (TKIs) or in subjects with Ph+ B-cell precursor (BCP) ALL or lymphoid blast phase CML (CML LBP), who have experienced resistance or intolera... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/27/2023
Locations: University of Texas MD Anderson Cancer Center, Houston, Texas
Conditions: Leukemia, Myeloid, Chronic, Myeloid Leukemia, Chronic Myeloid Leukemia, Philadelphia Positive Acute Lymphoblastic Leukemia, B Cell Precursor Type Acute Leukemia
Register for Updates
UTHealth Turner Syndrome Research Registry
NCT03185702
Recruiting
The investigators will conduct genetic comparisons between Turner Syndrome (TS) patients with and without Bicuspid Aortic Valve (BAV) to identify causative agents of BAV in people with TS. The investigators will correlate the patterns and prevalence of structural heart defects in TS women with emerging molecular data to identify patients who are at high risk for cardiovascular complications
Gender:
FEMALE
Ages:
All
Trial Updated:
11/27/2023
Locations: University of Texas Health Science Center Houston, Houston, Texas
Conditions: Turner Syndrome
Register for Updates
Pediatric Vasculitis Initiative
NCT02006134
Recruiting
Childhood chronic vasculitis describes a group of rare life-threatening diseases that have in common inflammation of blood vessels in vital organs such as kidneys, lungs and brain. Most knowledge about them comes from adult patients. Severe disease requires aggressive life-saving treatments with steroids and some cancer drugs which can themselves cause damage, and increase risks of cancer and severe infections. Conversely, milder disease can be treated with less toxic drugs. Different classifica... Read More
Gender:
ALL
Ages:
20 years and below
Trial Updated:
11/27/2023
Locations: Texas Children's Hospital, Houston, Texas
Conditions: Wegeners Granulomatosis (Granulomatosis With Polyangiitis), Microscopic Polyangiitis, Polyarteritis Nodosa, Takayasu Arteritis, Primary CNS Vasculitis, Unclassified Vasculitis, Eosinophilic Granulomatosis With Polyangiitis
Register for Updates
Nasal Compression Device Study for Epistaxis
NCT05789264
Recruiting
This study will explore how a nasal compression device compares to manual compression for stopping anterior nosebleeds. This will be a non-randomized controlled trial enrolling participants presenting to medical care for anterior nosebleeds. Participants will be assigned to receive either a nasal compression device or standard of care consisting of digital compression. Participants will be asked to complete survey questions to assess satisfaction with the care they received, comfort, and overall... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/20/2023
Locations: Next Level Urgent Care, Houston, Texas
Conditions: Epistaxis Nosebleed
Register for Updates
Prospective Database Registry Study of Scoliosis in Children With Cerebral Palsy
NCT00680264
Recruiting
The purpose of this study is to determine the radiographic and clinical outcomes of Scoliosis surgical and non-operative treatment in patients with Cerebral Palsy.
Gender:
ALL
Ages:
Between 8 years and 21 years
Trial Updated:
11/20/2023
Locations: Texas Scottish Rite Hospital, Dallas, Texas
Conditions: Cerebral Palsy, Scoliosis
Register for Updates
Appropriateness of Methodist Health System(MHS) Inter-facility Transfers of Traumatic Intracranial Subarachnoid Hemorrhage and Spontaneous Bleeds for Level-1 Advanced Surgical Intervention
NCT06136078
Recruiting
Brain injuries are common and challenging problems faced by emergency physicians. These diagnoses may include traumatic intracerebral hemorrhage, subarachnoid hemorrhage, ruptured cerebral aneurysms, unruptured cerebral aneurysms, and arteriovenous malformations, which require neurological, neurosurgical, and/or endovascular treatment.
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
11/15/2023
Locations: Clinical Research Institute at Methodist Health System, Dallas, Texas
Conditions: Traumatic Intracranial Subarachnoid Hemorrhage
Register for Updates
Penetrating Trauma Registry and Open Source Data
NCT06136273
Recruiting
Penetrating injuries comprise roughly 30% of Methodist Health System (MHS) trauma patients. Firearm-related events have become more prevalent in the past few years. Active shooter events, mass casualties, assaults, and homicide are more commonplace which leads to an increase of trauma patients needing management of penetrating injuries.
Gender:
ALL
Ages:
Between 16 years and 75 years
Trial Updated:
11/14/2023
Locations: Methodist Dallas Medical Center, Dallas, Texas
Conditions: Penetrating Trauma Registry and Open Source Data
Register for Updates
Clinical Outcome of Pericardial Closure Using Gentrix Following Cardiac Surgery
NCT06136182
Recruiting
A descriptive comparative project will be conducted to determine if there is a difference in outcomes for adult patients requiring pericardial reconstruction using CorMatrix compared to Gentrix
Gender:
ALL
Ages:
Between 18 years and 85 years
Trial Updated:
11/14/2023
Locations: Clinical Research Institute at Methodist Health System, Dallas, Texas
Conditions: Clinical Outcome of Pericardial Closure Using Gentrix
Register for Updates
DETEC® Esterase for Screening Wound Infection at Point of Care
NCT04614870
Recruiting
This non-interventional, single-blinded, prospective, observational study assesses the planar distribution of leukocyte esterase in wounds by placing wound exudates soaked wound dressings in the DETEC® Esterase device during routine wound care. The output of the device is correlated with clinical determination of infection to assess the device efficacy in identifying presumptive infections.
Gender:
ALL
Ages:
21 years and above
Trial Updated:
11/14/2023
Locations: Complex Healthcare Solutions, Arlington, Texas
Conditions: Diabetic Foot Ulcer, Venous Leg Ulcer, Pressure Ulcer
Register for Updates
DETEC® pH Point of Care Wound Diagnostic Test
NCT04614038
Recruiting
The purpose of this study is to determine the relationship between wound alkalinity and the non-healing status of chronic ulcer wounds. It is hypothesized that wounds with an alkaline environment as indicated by DETEC pH will have a high chance of not healing over 12 weeks of wound care.
Gender:
ALL
Ages:
21 years and above
Trial Updated:
11/14/2023
Locations: Complex Healthcare Solutions, Arlington, Texas
Conditions: Diabetic Foot Ulcer, Venous Leg Ulcer, Pressure Ulcer, Wound, Non-Healed
Register for Updates