Texas is currently home to 4879 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Houston, Dallas, San Antonio and Austin. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
A Study to Evaluate the Efficacy and Safety of Autogene Cevumeran With Nivolumab Versus Nivolumab Alone in Participants With High-Risk Muscle-Invasive Urothelial Carcinoma (MIUC)
Recruiting
The main purpose of the study is to evaluate the efficacy of adjuvant treatment with autogene cevumeran plus nivolumab compared with nivolumab in participants with high risk MIUC. In this study participants will be enrolled in a safety run-in phase to receive autogene cevumeran + nivolumab. This phase will be conducted to monitor and ensure the safety of study participants. After all participants in the safety run-in have been enrolled to receive autogene cevumeran + nivolumab, further particip... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/23/2025
Locations: MD Anderson Cancer Center, Houston, Texas
Conditions: Muscle Invasive Urothelial Carcinoma
A Phase 3 Study to Evaluate Petosemtamab Plus Pembrolizumab vs Pembrolizumab in First-line Treatment of Head and Neck Cancer (LiGeR - HN1)
Recruiting
This is a Phase 3 randomized, open-label study to evaluate the efficacy and safety of petosemtamab plus pembrolizumab vs pembrolizumab in first-line treatment of recurrent or metastatic PD-L1+ head and neck squamous cell carcinoma.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/23/2025
Locations: Site 22, Austin, Texas
Conditions: Head and Neck Squamous Cell Carcinoma
A Phase 2 Study of WU-CART-007, an Anti-CD7 Allogeneic CAR-T Cell Therapy in T-Cell Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma
Recruiting
The main purpose of this study is to evaluate the Composite Complete Remission Rate (CRc) of WU-CART-007 in Relapsed/Refractory (R/R) T-Cell Acute Lymphoblastic Leukemia (T-ALL)/Lymphoblastic Lymphoma (LBL) patients and to evaluate the efficacy of WU-CART-007 to induce complete Minimum Residual Disease (MRD) negative response
Gender:
ALL
Ages:
1 year and above
Trial Updated:
06/23/2025
Locations: MD Anderson Cancer Center, Houston, Texas
Conditions: T-cell Acute Lymphoblastic Leukemia, Lymphoblastic Lymphoma
Study of Sacituzumab Govitecan Versus Treatment of Physician's Choice in Participants With Endometrial Cancer After Platinum-Based Chemotherapy and Immunotherapy (ASCENT-GYN-01/GOG-3104/ENGOT-en26)
Recruiting
The goal of this clinical study is to find out how the study drug, sacituzumab govitecan (SG) works in participants with endometrial cancer who have received prior treatment with platinum-based chemotherapy and immunotherapy, versus the treatment of physician's choice (TPC). The primary objectives of this study are to evaluate the effect of SG compared to TPC on progression-free survival (PFS) as assessed by blinded independent central review (BICR) and overall survival (OS).
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
06/23/2025
Locations: University of Texas Southwestern Medical Center, Dallas, Texas
Conditions: Endometrial Cancer
Topical ENS-002 for Atopic Dermatitis in Adults
Recruiting
The goal of this study is to determine the safety and effects of ENS-002, a live biotherapeutic product (LBP) consisting of commensal, clonal, non-pathogenic bacteria in participants with atopic dermatitis.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/23/2025
Locations: Derm Research, Austin, Texas
Conditions: Atopic Dermatitis, Atopic Dermatitis Eczema
Phase 3 Study of T-DXd and Rilvegostomig Versus SoC in Advanced HER2-expressing Biliary Tract Cancer
Recruiting
The purpose of this study is to measure the efficacy and safety of T-DXd with rilvegostomig or T-DXd monotherapy compared with gemcitabine plus cisplatin and durvalumab in patients with advanced treatment naïve HER2-expressing BTC.
Gender:
ALL
Ages:
Between 18 years and 99 years
Trial Updated:
06/23/2025
Locations: Research Site, Austin, Texas
Conditions: Biliary Tract Cancer
A Virtual, Group-Based, Expressive Writing Intervention for Survivors of Adolescent and Young Adult Cancer
Recruiting
To learn more about the experiences of adolescent and young adult cancer survivors and investigate whether a group-based writing intervention can help to improve quality of life of adolescent and young adult cancer survivors.
Gender:
ALL
Ages:
Between 18 years and 39 years
Trial Updated:
06/23/2025
Locations: MD Anderson Cancer Center, Houston, Texas
Conditions: Cancer
A Study Describing the Efficacy and Safety of Belimumab Administered in Adult Participants With Early Systemic Lupus Erythematosus (SLE)
Recruiting
This is a prospective, open-label, single arm 3-year clinical study to describe the short-term and long-term efficacy and safety of belimumab in participants with autoantibody positive early SLE with ongoing disease activity despite stable initial SLE therapy.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/23/2025
Locations: GSK Investigational Site, Austin, Texas
Conditions: Systemic Lupus Erythematosus
A Phase I Study Investigating the Combination of the Ziftomenib, Venetoclax and Azacitidine in Pediatric Relapsed and Refractory Acute Leukemias
Recruiting
To find the highest safe dose of ziftomenib that can be combined with venetoclax and azacitidine in pediatric participants with acute leukemia that has certain types of genetic mutations (changes).
Gender:
ALL
Ages:
Between 2 years and 21 years
Trial Updated:
06/23/2025
Locations: MD Anderson Cancer Center, Houston, Texas
Conditions: Refractory Acute Leukemia, Pediatric Relapsed
A Study to Assess the Efficacy, Safety, and Pharmacokinetics of FNP-223 to Slow Progression of Progressive Supranuclear Palsy (PSP)
Recruiting
PROSPER trial is a trial to assess the efficacy of FNP-223 in slowing disease progression in participants with PSP as measured by the PSP Rating Scale (PSPRS) over 52 weeks and to assess the safety and tolerability of FNP-223 for 52 weeks in participants with PSP.
Gender:
ALL
Ages:
Between 50 years and 80 years
Trial Updated:
06/23/2025
Locations: Central Texas Neurology Consultants, Round Rock, Texas
Conditions: Progressive Supranuclear Palsy
The Golazo® Peripheral Atherectomy System for a Safe and Effective Atherectomy (GREAT Trial)
Recruiting
The objective of this study is to establish reasonable assurance of safety and effectiveness of the Golazo® Peripheral Atherectomy System when used as indicated in 159 subjects with symptomatic infrainguinal peripheral arterial disease (PAD) in up to 15 investigational sites in the U.S.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/23/2025
Locations: Hope Vascular & Podiatry, Houston, Texas
Conditions: Peripheral Arterial Disease
Phenotyping of Postural Orthostatic Tachycardia Syndrome (POTS)
Recruiting
This is an observational study to deeply phenotype the disorder of POTS using multiple testing modalities.
Gender:
ALL
Ages:
14 years and above
Trial Updated:
06/23/2025
Locations: UT Southwestern Medical Center, Dallas, Texas
Conditions: Postural Orthostatic Tachycardia Syndrome