California is currently home to 5930 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Los Angeles, San Francisco, San Diego and Sacramento. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Shifting Sleep Timing in Teens
Recruiting
The goal of this clinical trial is to determine whether a combination of a novel lighting intervention and a behavioral intervention are able to increase total sleep time in adolescents. The main questions this trial aims to answer are whether this combination therapy is able to meaningfully increase total sleep time in adolescents, and do so over a sustained period of time, and whether such a changes is associated with concomitant changes in mood and cognitive performance.
Gender:
All
Ages:
Between 14 years and 18 years
Trial Updated:
04/18/2023
Locations: Stanford University, Stanford, California
Conditions: Sleep Insufficiency, Sleep, Adolescent Behavior
A Clinical Investigation to Follow the Progress of Exuding Chronic Wounds Using Mepilex® Up as the Primary Dressing.
Recruiting
The goal of this clinical trial is to follow the progress of wounds in those with venous leg ulcers and diabetic foot ulcers while using an absorbent dressing called Mepilex Up. The main objective is to follow the progress of these wounds over time from initial visit to each follow-up visit. Participants will be asked to wear Mepilex Up dressing for up to 6 weeks of treatment or until healed, changed at every one-week interval.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/18/2023
Locations: Center for Clinical Research, Inc., Castro Valley, California
Conditions: Wounds, Wound of Skin, Wound Leg, Wound; Foot, Diabetic Foot Ulcer, Venous Leg Ulcer
Registry of Patients With a Diagnosis of Spinal Muscular Atrophy (SMA)
Recruiting
Spinal muscular atrophy (SMA) is a neurogenetic disorder caused by a loss or mutation in the survival motor neuron 1 gene (SMN1) on chromosome 5q13, which leads to reduced SMN protein levels and a selective dysfunction of motor neurons. SMA is an autosomal recessive, early childhood disease with an incidence of 1:10,000 live births. SMA is the leading cause of infant mortality due to genetic diseases. Until recently, the mainstay of treatment for these patients was supportive medical care. Howe... Read More
Gender:
All
Ages:
All
Trial Updated:
04/18/2023
Locations: Loma Linda University Health, Loma Linda, California
Conditions: Spinal Muscular Atrophy (SMA)
Parkinson Progression Marker Initiative Online (PPMI Online)
Recruiting
Parkinson Progression Marker Initiative Online (PPMI Online) is an observational study collecting participant reported information from people with and without Parkinson's disease (PD), for the goal of better understanding risk and predictive factors for PD. PPMI Online is part of the broader Parkinson Progression Marker Initiative aimed at identifying markers of disease progression for use in clinical trials of therapies to reduce progression of PD disability.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/17/2023
Locations: UCSF Movement Disorders and Neuromodulation Center (MDNC), San Francisco, California
Conditions: Parkinson Disease
Bedside Ultrasound of Gastric Contents in Pediatric Populations
Recruiting
Perioperative aspiration of gastric contents is a rare but serious adverse event. The risk of aspiration can be estimated by perioperative evaluation of stomach contents with ultrasound using a validated technique and scoring system. A lack of knowledge or familiarity is frequently cited by anesthesia providers as a rationale for not performing perioperative ultrasound assessments. The purpose of this study is to determine whether novice ultrasonography users (medical students, undergraduates, o... Read More
Gender:
All
Ages:
Between 2 years and 60 years
Trial Updated:
04/17/2023
Locations: LPCH/SHC, Stanford, California
Conditions: Gastric Contents
Neuroimaging Biomarkers for Predicting rTMS Response in OCD
Recruiting
This study evaluates an accelerated schedule of theta-burst stimulation using a Transcranial Magnetic Stimulation (TMS) device for treatment-resistant Obsessive Compulsive Disorder (OCD). In a randomized fashion, half the participants will receive accelerated theta-burst stimulation at the dorsomedial prefrontal cortex (DMPFC), while half will receive accelerated theta-burst stimulation at the right orbitofrontal (rOFC) site.
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
04/16/2023
Locations: Department of Psychiatry and Behavioral Sciences, Stanford School of Medicine, Stanford, California
Conditions: Obsessive-Compulsive Disorder
Virtual Reality Attention Management
Recruiting
Problems with distraction are widespread in the 21st century, but for people with developmental delays or behavioral challenges they can have more damaging effects. For example, susceptibility to distraction is associated with worse school and social performance, lower high school graduation rates, and increased incidence of serious accidents. The investigators' goal is to improve understanding of distractibility and develop a targeted treatment. The proposed intervention is based on models of h... Read More
Gender:
All
Ages:
Between 8 years and 12 years
Trial Updated:
04/16/2023
Locations: UC Davis MIND Institute, Sacramento, California
Conditions: ADHD
Mental Health Crises in Youth With IDDs
Recruiting
This study is an unmatched, case-control study of 150 youth (Ages 7-17) with a parent reported Intellectual Developmental Disability (IDD) who present to Rady Children's Hospital Emergency Department with a Mental Health Crisis (MHC). Rady Children's Institute for Genomic Medicine (RCIGM) will collect biological samples (such as blood) of these participants to study their genomes, medical and psychiatric profiles to better understand specific characteristics that may predispose them to MHC's. Th... Read More
Gender:
All
Ages:
Between 7 years and 17 years
Trial Updated:
04/14/2023
Locations: Rady Children's Hospital San Diego, San Diego, California
Conditions: Intellectual Disability
Water-based Activity to Enhance Recall in Veterans
Recruiting
This four-year study will evaluate the efficacy of an exercise training augmentation for cognitive training intervention to improve memory performance in Veterans with a diagnosis of amnestic Mild Cognitive Impairment (aMCI). This is a two-phased trial: 1) an exercise phase and 2) a cognitive training program. The exercise phase will be an aquatic based exercise program. A combination of exercise and cognitive training programs designed for persons without cognitive impairment have significantly... Read More
Gender:
All
Ages:
Between 50 years and 90 years
Trial Updated:
04/14/2023
Locations: VA Palo Alto Health Care System, Palo Alto, CA, Palo Alto, California
Conditions: Mild Cognitive Impairment
Efficacy and Safety of Masitinib Versus Placebo in the Treatment of ALS Patients
Recruiting
The objective is to compare the efficacy and safety of masitinib in combination with riluzole versus matched placebo in combination with riluzole for the treatment of Amyotrophic Lateral Sclerosis (ALS).
Gender:
All
Ages:
Between 18 years and 81 years
Trial Updated:
04/14/2023
Locations: University of Southern California, Los Angeles, California
Conditions: Amyotrophic Lateral Sclerosis
Comparing Operative vs Non Operative Treatment for Pilonidal Disease
Recruiting
The goal is to evaluate whether surgical excision of the pilonidal disease is needed after resolution of the initial symptoms when the patient follows regular hair removal regimen such as laser epilation.
Gender:
All
Ages:
8 years and above
Trial Updated:
04/13/2023
Locations: Stanford University School of Medicine, Palo Alto, California
Conditions: Pilonidal Disease
Vicryl Rapide Versus Nonabsorbable Suture
Recruiting
This will be a prospective, randomized controlled trial assessing noninferiority of Vicryl Rapide compared to nonabsorbable suture. The study will be conducted in the Community Regional Medical Center emergency department (ED). The aim of this study, then, is to prospectively determine if 3-month cosmesis for traumatic laceration repair of trunk/extremity lacerations in adult patients with Vicryl Rapide is noninferior to nonabsorbable suture.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/13/2023
Locations: Community Regional Medical Center, Fresno, California
Conditions: Traumatic Lacerations