California is currently home to 5955 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Los Angeles, San Francisco, San Diego and Sacramento. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Efficacy of Diuretics in Kidney Disease
Recruiting
This study will determine the efficacy of diuretics in patients with chronic kidney disease.
Gender:
All
Ages:
18 years and above
Trial Updated:
09/29/2022
Locations: Stanford University, Palo Alto, California
Conditions: Chronic Kidney Disease, End Stage Renal Disease
Efficacy of Twice Weekly Hemodialysis in Patients With Residual Kidney Function
Recruiting
The study will determine the efficacy of twice weekly hemodialysis in patients with residual kidney function.
Gender:
All
Ages:
Between 18 years and 85 years
Trial Updated:
09/29/2022
Locations: VA Palo Alto Health Care System, Palo Alto, California
Conditions: Hemodialysis, Kidney Failure, Chronic
Differential Target Multiplexed Spinal Cord Stimulation (DTM-SCS®) Real World Outcomes
Recruiting
The UPGRADE registry will capture long-term, real-world outcomes to understand the effect of Differential Target Multiplexed (DTM®) programming in the Spinal Cord Stimulation (SCS) implanted population on the management of chronic pain, primarily on its use for trunk and/or limb pain. The clinical study is sponsored by Celéri Health and is funded through a financial grant from Medtronic's External Research Program. The registry study will be conducted across approximately 25 centers in the Unite... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
09/28/2022
Locations: NuVation Pain Group - Buena Park, Buena Park, California
Conditions: Chronic Pain
Comparing Mobile Health Strategies to Improve Pre-exposure Prophylaxis Use (PrEP) for HIV Prevention
Recruiting
The purpose of this study is to compare the effectiveness of two mobile health technologies (text messaging or a mobile app) designed to help people take HIV pre-exposure prophylaxis (PrEP) as directed by the clinic. PrEP is the use of a daily anti-HIV medications by HIV-negative people to help prevent HIV infection.
Gender:
All
Ages:
15 years and above
Trial Updated:
09/27/2022
Locations: Bridge HIV, San Francisco Department of Public Health, San Francisco, California
Conditions: HIV Infections, Sexually Transmitted Diseases
tDCS and Cognitive Training in Active Duty Service Members With Mild TBI: A Pilot Study
Recruiting
The proposed study will evaluate a new approach to cognitive rehabilitation of mild traumatic brain injury (mTBI) using a brain stimulation technique called transcranial direct current stimulation (tDCS). Specifically, we will investigate how tDCS combined with cognitive training improves deficits to attention and working memory in Active Duty Service Members with a history of mild traumatic brain injury (TBI). Measures of attention-related brain activity, neurocognitive assessments, and self-re... Read More
Gender:
All
Ages:
Between 18 years and 55 years
Trial Updated:
09/26/2022
Locations: Naval Medical Center San Diego, San Diego, California
Conditions: Brain Concussion, Brain Trauma, Attention Concentration Difficulty, Brain Injuries, Brain Injuries, Traumatic, Neurocognitive Dysfunction, Attention Impaired, Memory Impairment, Mild Traumatic Brain Injury, Mild Cognitive Impairment
Physiologic Signals and Signatures With the Accuryn Monitoring System - The Accuryn Registry
Recruiting
The Accuryn Registry Study is an open-ended, global, multi-center, retrospective and prospective, single-arm data collection study with an FDA cleared device. The target population are cardiovascular surgery patients. Physiologic data measurements will be collected from enrolled subjects using electronic medical records and data streams via the Accuryn Monitoring System.
Gender:
All
Ages:
18 years and above
Trial Updated:
09/26/2022
Locations: Cedars-Sinai Medical Center, Los Angeles, California
Conditions: Intraabdominal Hypertension, Abdominal Compartment Syndrome, Acute Kidney Injury, Cardiovascular Surgery
Study for the Evaluation of the Feasibility of Applying Advanced MRI Scanning in Pediatric Clinical Practice
Recruiting
The purpose of this research study is to evaluate the feasibility in conducting advanced MRI sequences in a pediatric clinical setting. The study will be observational in nature, and will only evaluate the studies of pediatric patients who have already been prescribed an advanced MRI for clinical neurological purposes. The only difference for the subject in participating in this study is that the data and information about their scan can be used and disclosed for research purposes, i.e. understa... Read More
Gender:
All
Ages:
All
Trial Updated:
09/26/2022
Locations: Neurological Associates of West Los Angeles, Santa Monica, California
Conditions: Neurodevelopmental Disorders
Expression of Stress Markers During Meth Treatment (EXPRESS+)
Recruiting
This is a non-randomized behavioral trial that aims to investigate whether changes in inflammatory and type I IFN expression coincide with changes in methamphetamine use and viral load over the course of 12 weeks in HIV-positive people assigned male at birth with and without methamphetamine use disorder.
Gender:
Male
Ages:
Between 18 years and 45 years
Trial Updated:
09/23/2022
Locations: UCLA Vine Street Clinic, Los Angeles, California
Conditions: Substance-Related Disorders, HIV
Evaluation of The Comfort of Orthokeratology Lenses Fit Using A New Software
Recruiting
As new orthokeratology fitting software emerges onto the market, it is of interest to assess their usefulness in guiding eye practitioners with lens fit. The goal of this study is to evaluate the comfort of Paragon orthokeratology lenses when they are fit using the new Procornea software.
Gender:
All
Ages:
Between 6 years and 35 years
Trial Updated:
09/22/2022
Locations: 4S Eyecare and Optometry, San Diego, California
Conditions: Myopia
Home With TablO outcoMEs (HOME) Registry
Recruiting
Prospective, multicenter, single arm, post-market study to evaluate real world clinical outcomes in ESRD patients receiving in-home dialysis on the Tablo Hemodialysis System.
Gender:
All
Ages:
15 years and above
Trial Updated:
09/22/2022
Locations: Satellite Healthcare, Inc., San Jose, California
Conditions: End Stage Renal Disease
Determining the Utility of a Behavioral Intervention in Chronic Migraine
Recruiting
This proposal will involve a pilot study to evaluate the feasibility, acceptability, and outcomes of a lifestyle behavior protocol in managing chronic migraine. Additionally, the proposal will investigate biomolecules that are uniquely involved in chronic migraine patients who respond to the protocol. Successful completion of this proposal will inform the design of a future full-scale behavioral clinical trial to control chronic migraine.
Gender:
All
Ages:
18 years and above
Trial Updated:
09/20/2022
Locations: Stanford University, Stanford, California
Conditions: Migraine, Headache, Migraine Disorders, Chronic Migraine, Lifestyle Factors, Headache Disorders
A Study Evaluating An Integrated Pharmacy Digital Diary and Delivery Strategy to Increase PrEP Use Among MSM and TGW
Recruiting
The PrEP 3D randomized controlled trial (RCT) will study the effectiveness of the PrEP-3D app compared to standard of care for starting pre-exposure prophylaxis (PrEP), continuing PrEP, and adherence to PrEP.
Gender:
Male
Ages:
18 years and above
Trial Updated:
09/16/2022
Locations: Bridge HIV, San Francisco Department of Public Health, San Francisco, California
Conditions: HIV Prevention, Pre-exposure Prophylaxis (PrEP), Risk Reduction, Adherence, Medication