California is currently home to 5930 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Los Angeles, San Francisco, San Diego and Sacramento. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Physiologic Signals and Signatures With the Accuryn Monitoring System - The Accuryn Registry
Recruiting
The Accuryn Registry Study is an open-ended, global, multi-center, retrospective and prospective, single-arm data collection study with an FDA cleared device. The target population are cardiovascular surgery patients. Physiologic data measurements will be collected from enrolled subjects using electronic medical records and data streams via the Accuryn Monitoring System.
Gender:
All
Ages:
18 years and above
Trial Updated:
09/26/2022
Locations: Cedars-Sinai Medical Center, Los Angeles, California
Conditions: Intraabdominal Hypertension, Abdominal Compartment Syndrome, Acute Kidney Injury, Cardiovascular Surgery
Study for the Evaluation of the Feasibility of Applying Advanced MRI Scanning in Pediatric Clinical Practice
Recruiting
The purpose of this research study is to evaluate the feasibility in conducting advanced MRI sequences in a pediatric clinical setting. The study will be observational in nature, and will only evaluate the studies of pediatric patients who have already been prescribed an advanced MRI for clinical neurological purposes. The only difference for the subject in participating in this study is that the data and information about their scan can be used and disclosed for research purposes, i.e. understa... Read More
Gender:
All
Ages:
All
Trial Updated:
09/26/2022
Locations: Neurological Associates of West Los Angeles, Santa Monica, California
Conditions: Neurodevelopmental Disorders
Evaluation of The Comfort of Orthokeratology Lenses Fit Using A New Software
Recruiting
As new orthokeratology fitting software emerges onto the market, it is of interest to assess their usefulness in guiding eye practitioners with lens fit. The goal of this study is to evaluate the comfort of Paragon orthokeratology lenses when they are fit using the new Procornea software.
Gender:
All
Ages:
Between 6 years and 35 years
Trial Updated:
09/22/2022
Locations: 4S Eyecare and Optometry, San Diego, California
Conditions: Myopia
Home With TablO outcoMEs (HOME) Registry
Recruiting
Prospective, multicenter, single arm, post-market study to evaluate real world clinical outcomes in ESRD patients receiving in-home dialysis on the Tablo Hemodialysis System.
Gender:
All
Ages:
15 years and above
Trial Updated:
09/22/2022
Locations: Satellite Healthcare, Inc., San Jose, California
Conditions: End Stage Renal Disease
Determining the Utility of a Behavioral Intervention in Chronic Migraine
Recruiting
This proposal will involve a pilot study to evaluate the feasibility, acceptability, and outcomes of a lifestyle behavior protocol in managing chronic migraine. Additionally, the proposal will investigate biomolecules that are uniquely involved in chronic migraine patients who respond to the protocol. Successful completion of this proposal will inform the design of a future full-scale behavioral clinical trial to control chronic migraine.
Gender:
All
Ages:
18 years and above
Trial Updated:
09/20/2022
Locations: Stanford University, Stanford, California
Conditions: Migraine, Headache, Migraine Disorders, Chronic Migraine, Lifestyle Factors, Headache Disorders
A Study Evaluating An Integrated Pharmacy Digital Diary and Delivery Strategy to Increase PrEP Use Among MSM and TGW
Recruiting
The PrEP 3D randomized controlled trial (RCT) will study the effectiveness of the PrEP-3D app compared to standard of care for starting pre-exposure prophylaxis (PrEP), continuing PrEP, and adherence to PrEP.
Gender:
Male
Ages:
18 years and above
Trial Updated:
09/16/2022
Locations: Bridge HIV, San Francisco Department of Public Health, San Francisco, California
Conditions: HIV Prevention, Pre-exposure Prophylaxis (PrEP), Risk Reduction, Adherence, Medication
Envi™-SR Randomized Controlled Trial for Endovascular Treatment of Ischemic Stroke
Recruiting
The study objective is to examine and compare clinical outcomes, as measured by Modified Rankin Scale (mRS) at 90 days (± 15 days) post treatment, and related performance characteristics of the Envi™-SR and concurrent parallel Control Devices currently cleared by the U.S. FDA for treatment of stroke.
Gender:
All
Ages:
18 years and above
Trial Updated:
09/15/2022
Locations: Providence Medical Foundation, Irvine, California
Conditions: Acute Ischemic Stroke
Blossom Smart Expander Technology in Breast Reconstruction in Participants With Breast Cancer Undergoing Mastectomy
Recruiting
This phase 1 trial studies how well Blossom Smart Expander Technology works in breast reconstruction in participants with breast cancer undergoing mastectomy. Blossom Smart Expander Technology allows for slow and continuous injection of small amounts of saline, from an external pouch and based on precise pressure and volume measurements, into breast expander implants. It may help in achieving the same reconstructive goals as conventional tissue expansion in a shorter period of time and while avo... Read More
Gender:
Female
Ages:
18 years and above
Trial Updated:
09/09/2022
Locations: Stanford University Medical Center, Stanford, California
Conditions: Breast Carcinoma, Breast Disorder
ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation
Recruiting
The purpose of ORACLE is to demonstrate the ability of a novel ctDNA assay developed by Guardant Health to detect recurrence in individuals treated for early-stage solid tumors. It is necessary that ctDNA test results are linked to clinical outcomes in order to demonstrate clinical validity for recurrence detection and explore its value in a healthcare environment subject to cost containment.
Gender:
All
Ages:
18 years and above
Trial Updated:
09/07/2022
Locations: Redwood City, Redwood City, California
Conditions: Bladder Carcinoma, Ureter Carcinoma, Renal Pelvis Carcinoma, Non-small Cell Lung Cancer, Invasive Breast Carcinoma, Cutaneous Melanoma, Esophageal Carcinoma, Gastroesophageal Junction Carcinoma, Gastric Adenocarcinoma, Pancreatic Adenocarcinoma, Squamous Cell Carcinoma of the Head and Neck, Epithelial Ovarian Carcinoma, Fallopian Tube Carcinoma, Endometrial Carcinoma, Renal Cell Carcinoma
Safety, Tolerability, and Efficacy of AXA1125 in NASH With Fibrosis
Recruiting
This study will compare the effects of AXA1125, an orally active mixture of amino acids, compared to placebo, on improving fat and inflammation (steatohepatitis) as well as fibrosis in subjects with non alcoholic steatohepatitis (NASH). as well as the safety and tolerability of AXA1125. Subjects will take one of two different doses of AXA1125 or a placebo twice daily, and a liver biopsy will be done at the beginning and end of the 48-week study.
Gender:
All
Ages:
18 years and above
Trial Updated:
09/07/2022
Locations: San Fernando Valley Health Institute, Canoga Park, California
Conditions: Non Alcoholic Steatohepatitis (NASH)
Electron Beam Intraoperative Radiation Therapy Following Chemoradiation in Patients With Pancreatic Cancer With Vascular Involvement
Recruiting
This research study is studying an intervention as a possible treatment for pancreatic cancer.
Gender:
All
Ages:
18 years and above
Trial Updated:
09/07/2022
Locations: University of California, Irvine, Irvine, California
Conditions: Pancreas Cancer
MR-Guided Focused Ultrasound in the Treatment of Focal Epilepsy (EP001)
Recruiting
The purpose of this study is to evaluate the feasibility, safety, and initial effectiveness of Exablate thermal ablation of a focal epileptic target area in the brain of patients suffering from medication-refractory epilepsy, using the Exablate transcranial system to produce multiple sonications targeted in the focus of interest. The investigators will establish the feasibility and collect data to establish the basic safety of this type of treatment as the basis for later studies that will evalu... Read More
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
09/07/2022
Locations: Stanford University, Stanford, California
Conditions: Epilepsy