California is currently home to 5952 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Los Angeles, San Francisco, San Diego and Sacramento. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Artisan Aphakia Lens for the Correction of Aphakia (Secondary) in Adults
Recruiting
This study will determine the safety and effectiveness of the Artisan Aphakia Lens when used as a secondary implant to correct aphakia in adults.
Gender:
All
Ages:
22 years and above
Trial Updated:
06/24/2022
Locations: Assil Eye Institute, Beverly Hills, California
Conditions: Aphakia
Tabelecleucel for Solid Organ or Allogeneic Hematopoietic Cell Transplant Participants With Epstein-Barr Virus-Associated Post-Transplant Lymphoproliferative Disease (EBV+ PTLD) After Failure of Rituximab or Rituximab and Chemotherapy
Recruiting
The purpose of this study is to determine the clinical benefit and characterize the safety profile of tabelecleucel for the treatment of Epstein-Barr virus-associated post-transplant lymphoproliferative disease (EBV+ PTLD) in the setting of (1) solid organ transplant (SOT) after failure of rituximab and rituximab plus chemotherapy or (2) allogeneic hematopoietic cell transplant (HCT) after failure of rituximab.
Gender:
All
Ages:
All
Trial Updated:
06/23/2022
Locations: City of Hope (Adults and Pediatrics), Duarte, California
Conditions: Epstein-Barr Virus+ Associated Post-transplant Lymphoproliferative Disease (EBV+ PTLD), Solid Organ Transplant Complications, Lymphoproliferative Disorders, Allogeneic Hematopoietic Cell Transplant, Stem Cell Transplant Complications
Evaluation of the Effectiveness of PermeaDerm® (PD) as Compared to Mepilex Ag®
Recruiting
A total of 68 adult and pediatric patients who suffer from at least one discrete partial thickness thermal burn wound (Grade II) will be recruited. Subjects will be randomized (1:1) to either PermeaDerm® or Mepilex Ag®. Evaluations will occur at 7, 14 and 21 days with long term follow-up at 6 and 12 months.
Gender:
All
Ages:
75 years and below
Trial Updated:
06/21/2022
Locations: University of California, Davis, Sacramento, California
Conditions: Thermal Burn
Papillary Balloon Dilation Versus Intraductal Lithotripsy
Recruiting
Our aim is to compare the efficacy, safety, procedural time required, and costs of a strategy initially employing cholangioscopy guided intraductal lithotripsy (laser/electrohydraulic lithtripsy (EHL)) versus a strategy initially using papillary dilation for removal of large bile duct stones.
Gender:
All
Ages:
Between 18 years and 115 years
Trial Updated:
06/14/2022
Locations: Keck Hospital of USC, Los Angeles, California
Conditions: Choledocholithiasis
Los Angeles Prospective GI Biliary and EUS Series
Recruiting
Endoscopic retrograde cholangiopancreatography and endoscopic ultrasound are increasingly being used to manage complex disease of the bile duct, pancreas and cancer. Gastroenterology patients at the Los Angeles County Hospital presents a unique and diverse patient population. Our aim is to study the biochemical, radiographic, and clinical predictors of bile duct stones. Exploratory aims include the study of the management of cholangitis, bile leaks, GI cancer diagnosis and management, and the m... Read More
Gender:
All
Ages:
All
Trial Updated:
06/14/2022
Locations: Los Angeles County Hospital, Los Angeles, California
Conditions: Biliary Disease, Pancreatitis, Gastrointestinal Neoplasms
Validation of myStrength's Macropersonalization Engine
Recruiting
This is a study to validate myStrength's macropersonalization algorithm. Specifically, the study seeks to answer: Does myStrength's macropersonalization algorithm match what a clinician would offer as a diagnosis following an expert assessment? Participants will be treatment-seeking adults, ages 18 to 65, recruited from an evidence-based group psychotherapy practice. Participants will be asked to complete myStrength onboarding and a clinician-conducted initial assessment. Inter-rater reliability... Read More
Gender:
All
Ages:
Between 18 years and 85 years
Trial Updated:
06/09/2022
Locations: Pacific Anxiety Group, Menlo Park, California
Conditions: Depression, Anxiety, Trauma
LIFE Cancer Survivorship Database for Pediatric Cancer
Recruiting
The purpose of this study is to develop a mechanism for utilizing the comprehensive clinical database of childhood cancer survivors at Childrens Hospital Los Angeles (CHLA) for research purposes. Using clinical information obtained from follow-up visits of childhood cancer survivors, the database will focus on interventions to improve health status and health-related quality of life in childhood cancer survivors. This study allows for establishment and analyses of a research database for LIFE su... Read More
Gender:
All
Ages:
All
Trial Updated:
06/09/2022
Locations: Children's Hospital Los Angeles, Los Angeles, California
Conditions: Pediatric Cancer
Intervention Development and Pilot Study to Prevent Untreated Native Hawaiian and Pacific Islander Opioid Use Disorder
Recruiting
This study will design and pilot/feasibility test a culturally grounded intervention to increase the treatment seeking of Pacific Islanders with opioid use disorders in formal services.
Gender:
All
Ages:
18 years and above
Trial Updated:
06/08/2022
Locations: UC Riverside, Riverside, California
Conditions: Opioid-use Disorder
Engaging Pacific Islanders in Mental Health Treatment
Recruiting
This study will create and pilot test a culturally grounded intervention (Talking Story) to increase mental health treatment seeking among Pacific Islanders with mental disorders (e.g., major depressive disorder, generalized anxiety disorder).
Gender:
All
Ages:
18 years and above
Trial Updated:
06/08/2022
Locations: UC Riverside, Riverside, California
Conditions: Depression, Anxiety Disorders
Serranator Recoil Study
Recruiting
The study objective is to assess the ability to define and measure post treatment recoil in infrapopliteal arteries. Preliminary evidence as to the differences between serration angioplasty and standard balloon angioplasty as defined by post treatment recoil, lumen gain, and dissection will be collected.
Gender:
All
Ages:
18 years and above
Trial Updated:
06/07/2022
Locations: Stanford University, Palo Alto, California
Conditions: Peripheral Arterial Disease, Critical Limb Ischemia
2021 PMT iAge® Intervention Trial by Edifice Health
Recruiting
This is a decentralized, double-blind, randomized, placebo-controlled study to assess the effectiveness of different dietary supplements in decreasing systemic chronic inflammation (SCI) and lowering inflammatory age (iAge®). iAge® is a metric for age-related chronic inflammation and immune function decline calculated from a standard blood draw utilizing immune phenotyping and artificial intelligence algorithms. SCI is a natural process that occurs within the body. It is believed to accelerate t... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
06/07/2022
Locations: La Follette Ob-Gyn & Aesthetics, Greenbrae, California
Conditions: Chronic Inflammation, Inflammaging
Erector Spinae Plane Block Catheters and Intrathecal Morphine for Hepatic Resection
Recruiting
To determine whether the addition of erector spinae plane (ESP) catheters to existing multimodal analgesic regimen with intrathecal morphine provides superior postoperative analgesia in patients undergoing hepatic resection compared with patients not receiving ESP catheters.
Gender:
All
Ages:
18 years and above
Trial Updated:
06/06/2022
Locations: University of California, San Diego, San Diego, California
Conditions: Hepatic Resection, Acute Pain, Anesthesia, Anesthesia, Local