California is currently home to 5797 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Los Angeles, San Francisco, San Diego and Sacramento. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
To Evaluate the Efficacy and Safety of Parsaclisib and Ruxolitinib in Participants With Myelofibrosis (LIMBER-313)
Recruiting
The purpose of the study is to compare the efficacy of parsaclisib when combined with ruxolitinb versus placebo combined with ruxolitinib in participants with myelofibrosis.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/24/2021
Locations: CCARE, Fresno, California
Conditions: Myelofibrosis, Primary Myelofibrosis, Post Essential Thrombocythemia Myelofibrosis, Post Polycythemia Vera Myelofibrosis
Evaluating the Impact of Incentives on Clinical Trial Participation
Recruiting
The objective of this study is to investigate the impact of incentives on clinical trial participation. 1) characterize key stakeholders' views on and assessment of incentives, 2) reach consensus among stakeholders on the factors to be considered when choosing incentives and their relative importance, 3) pilot test using vignettes for incentive decision making. We hypothesize that potential study participants make trade-offs regarding the characteristics of a research study when deciding whether... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
03/18/2021
Locations: UC Riverside, Riverside, California
Conditions: Hiv, Aging, Incentives
A Study to Evaluate Safety and PK of Multiple Doses of LT3001 Drug Product and Drug-drug Interaction in Healthy Subjects
Recruiting
This Phase 1 study is planned to establish the clinical safety and pharmacokinetics profile of multiple dose of LT3001 drug product and to investigate drug interactions of LT3001 with potential concomitant medications in healthy subjects.
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
03/17/2021
Locations: Lumosa Phase 1 Unit, Cypress, California
Conditions: Acute Ischemic Stroke
Glucose Differences Between the Left Arm and Right Arm in Diabetic Patients Using a Continuous Glucose Monitor
Recruiting
Continuous glucose monitoring (CGM) is an emerging field for diabetes management. CGMs are small devices primarily placed on a patient's upper arm that allow providers and patients to individualize therapy by looking at real time glucose levels. While the accuracy of these devices is extensively researched, there are no large-scale studies evaluating the differences between left and right arm glucose readings in the diabetic population. Additionally cinnamon and aloe vera are supplements commonl... Read More
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
03/05/2021
Locations: Manshadi Heart Institute, Inc., Stockton, California
Conditions: Diabetes
The Use of a Sustained Dynamic Compression Intramedullary Nail for Subtalar Arthrodesis
Recruiting
The purpose of this study is to determine the clinical efficacy of a novel dynamic sustained compression intramedullary nail for subtalar (talocalcaneal) arthrodesis.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/03/2021
Locations: University of California, Davis Medical Center, Sacramento, California
Conditions: Foot Arthritis
Study of External Neuromodulation to Improve Signs and Symptoms of Dry Eye in Visual Display Terminal Users
Recruiting
Two study arms - sham and treatment; There will be a cross over of the sham group to the treatment group at day 15.
Gender:
All
Ages:
Between 18 years and 69 years
Trial Updated:
02/17/2021
Locations: Fishman Vision, Palo Alto, California
Conditions: Visual Display Users With Previously Undiagnosed Dry Eye
Evaluation of the PhageTech Virus BioResistor
Recruiting
To evaluate the effectiveness of the PhageTech Virus BioResistor to detect bladder cancer biomarkers.
Gender:
All
Ages:
18 years and above
Trial Updated:
02/12/2021
Locations: Providence Saint John's Health Center and the Saint John's Cancer Institute, Santa Monica, California
Conditions: Bladder Cancer
In-Home Sleep Monitoring to Detect Suicide Risk in Veterans
Recruiting
This research will assess the ability of nightly objective sleep scheduling and sleep heart rate data to predict variation in suicidal ideation in U.S. military veterans identified as high-risk according to actuarial and/or clinical indicators. These data will be recorded using one of two low-cost, commercial, zero-burden, mattress actigraphic systems that enable remote, centralized, data access. Participants will be veterans accrued both from the REACH VET and local high-risk lists, a process i... Read More
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
02/03/2021
Locations: VA Palo Alto Health Care System, Palo Alto, California
Conditions: Suicidal Ideation, Sleep Disturbance
Validation of Cognitive Enhancement Techniques for Mild Traumatic Brain Injury
Recruiting
With an average of 21,000 diagnosed brain injuries each year among military personnel, traumatic brain injury (TBI) remains a major health concern for the United States Military Health System. Mild traumatic brain injury (mTBI) is the most common type of brain injury sustained by military personnel and may result in chronic cognitive impairment.Unfortunately, many service members (SMs) have a history of multiple head injuries as well as psychological co-morbidities that negatively influence reco... Read More
Gender:
All
Ages:
All
Trial Updated:
02/01/2021
Locations: Naval Hospital Camp Pendleton, Oceanside, California
Conditions: Mild Traumatic Brain Injury
An Active and Placebo-Controlled Study of Brazikumab in Participants With Moderately to Severely Active Ulcerative Colitis
Recruiting
The present study D5272C00001 (Legacy # 3151-201-008) seeks to evaluate the efficacy and safety of brazikumab versus placebo in patients with moderately to severely active UC and will include assessments of clinical responses as demonstrated by improvement of symptoms and of colonic mucosal appearance as observed on endoscopy.
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
01/19/2021
Locations: Research Site, Chula Vista, California
Conditions: Ulcerative Colitis
The Effect of Cooling on Sclerotherapy Efficacy
Recruiting
The primary objective of this study is to evaluate the efficacy of sclerotherapy with forced-air cooling during treatment.
Gender:
All
Ages:
Between 25 years and 75 years
Trial Updated:
12/28/2020
Locations: West Dermatology Research Center/Cosmetic Laser Dermatology, San Diego, California
Conditions: Leg Veins
Open-Label Extension Study of BION-1301 in IgA Nephropathy
Recruiting
This is an open-label extension (OLE) study to evaluate the safety, pharmacokinetics (PK), pharmacodynamics (PD), and clinical activity of BION-1301 in adults with IgA nephropathy
Gender:
All
Ages:
18 years and above
Trial Updated:
12/22/2020
Locations: Amicis Research Center, Northridge, California
Conditions: IgA Nephropathy