California is currently home to 5957 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Los Angeles, San Francisco, San Diego and Sacramento. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Transcatheter Aortic Valve Replacement (TAVR) Double Balloon Valvuloplasty
Recruiting
In this study, the investigators evaluate whether routine double inflation of the valve could have a lasting impact. The investigators hypothesize that a routine second reinflation of the balloon, or "double tap", will improve flow across the valve when compared to a single inflation. The investigators hypothesize that "double tap" (1) will decrease mean gradient between first and second inflation during the procedure, (2) will decrease mean gradient on immediate post procedure and 30 day postpr... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
12/28/2021
Locations: Community Memorial Hospital, Ventura, California
Conditions: Aortic Valve Stenosis
POC Study to Evaluate the Performance of the AcuVid COVID-19 Rapid Antigen Saliva Test
Recruiting
The AcuVid COVID-19 Rapid Antigen Saliva Test is a lateral flow immunoassay to detect SARS-CoV-2 nucleocapsid antigens in human saliva specimens from individuals suspected of COVID-19 by their healthcare provider within the first seven days of symptom onset, or from individuals without symptoms or other epidemiological reasons to suspect. The AcuVid COVID-19 Rapid Antigen Saliva Test performance will be compared to a high sensitivity FDA EUA approved RT-PCR COVID-19 test. Nasopharyngeal (for RT... Read More
Gender:
All
Ages:
12 years and above
Trial Updated:
12/21/2021
Locations: Covid Clinic Inc., Modesto, California
Conditions: COVID-19
Effect of Prehabilitation on Surgical Outcomes of Abdominally-based Plastic Surgery Procedures
Recruiting
The purpose of this study is to determine whether a program to optimize patient physical fitness and nutrition ("prehabilitation") prior to and after plastic surgery involving the abdomen improves surgical outcomes. The investigators hope to determine how a multimodal peri-operative prehabilitation program can be most effective in engaging and motivating patients to physically and mentally get ready for an abdominally-based plastic surgery operation. The overall goal is to determine if this prog... Read More
Gender:
All
Ages:
19 years and above
Trial Updated:
12/14/2021
Locations: Stanford Cancer Center South Bay, San Jose, California
Conditions: Ventral Hernia, Panniculus, Abdominoplasty, Flap Reconstruction
Trigger Point Injections Versus Lidocaine Patch for Myofascial Pain in the Emergency Department
Recruiting
The aim of this trial is to investigate the efficacy of trigger point injections with 1% lidocaine in reducing myofascial back and neck pain in the Emergency Department compared to lidocaine patches 5%.
Gender:
All
Ages:
18 years and above
Trial Updated:
12/08/2021
Locations: Emergency Room at UCI Medical Center, Orange, California
Conditions: Myofascial Trigger Point Pain, Myofacial Pain
Single-Blind Study of STAT-205 in Mild COVID-19
Recruiting
This is a randomized, single blind, study. Males and females meeting inclusion criteria who have symptoms of mild COVID-19 and in whom a positive PCR result for SARS-CoV-2 is obtained may be enrolled to the study treatment within 72 hours of the positive PCR result. Eligible patients are those considered to be at high risk for COVID-19 disease progression. This includes patients ≥ 65 years of age or with any one or more of certain medical conditions including: cancer, COPD, cardiovascular diseas... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
12/07/2021
Locations: Loma Linda University, Loma Linda, California
Conditions: COVID-19
COVID-19 Administration of Single-Dose Subcutaneous Anti- Spike(s) SARS-CoV-2 Monoclonal Antibodies Casirivimab and Imdevimab in High-Risk Pediatric Participants Under 12 Years of Age
Recruiting
The primary objective of the study is to characterize the concentrations of casirivimab+imdevimab in serum over time after a single subcutaneous (SC) administration The secondary objectives of the study are: To assess the safety and tolerability of SC or single administration of casirivimab+imdevimab To assess the occurrence of grade ≥3 injection site reactions and grade ≥3 hypersensitivity reactions, in participants treated with SC doses of casirivimab+imdevimab To assess the immunogenicity o... Read More
Gender:
All
Ages:
12 years and below
Trial Updated:
12/06/2021
Locations: Advanced Research Center, Inc, Anaheim, California
Conditions: COVID-19
Study to Assess Switching to B/F/TAF in Treatment Experienced People With HIV Who Are at Least 65 Years of Age
Recruiting
To assess patient reported treatment satisfaction and medication tolerability in virologically suppressed HIV-1 infected adults who are at least 65 years of age who switch to a bictegravir/emtricitabine/tenofovir alafenamide (B/F/TAF) fixed-dose combination regimen.
Gender:
All
Ages:
65 years and above
Trial Updated:
12/06/2021
Locations: DAP Health, Palm Springs, California
Conditions: HIV-1-infection
A Retrospective Study to Examine the Effect of CMF Stimulation on Primary ACDF Patients
Recruiting
A retrospective parallel group comparison study to support expansion of the indication of the company's FDA approved Spinalogic™ device to include the cervical spine. The SpinalogicTM device was initially approved by FDA as an adjunct to one- or two-level lumbar fusion (P910066/S011). It is a non-invasive bone growth stimulator (BGS) that generates a combined magnetic field (CMF) that has been proven to accelerate bone healing and fusion in the lumbar spine.
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
12/06/2021
Locations: SIOSD, San Diego, California
Conditions: Degeneration of Cervical Intervertebral Disc
Prediction of Outcomes After Surgery for Unruptured Intracranial Aneurysms
Recruiting
Accurate preoperative identification of patients at high risk for adverse outcomes would be clinically advantageous, as it would allow enhanced resource preparation, better surgical decision-making, enhanced patient education and informed consent, and potentially even modification of certain modifiable risk factors. The aim of the Prediction of adverse events after microsurgery for intracranial unruptured aneurysms (PRAEMIUM) study is therefore to develop and externally validate a clinically app... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
12/05/2021
Locations: UCLA, Los Angeles, California
Conditions: Aneurysm, Brain
Communities Fighting COVID-19!
Recruiting
To create and evaluate effective COVID-19 testing uptake strategies that focus on underserved individuals who are exposed but have not accessed testing, and underserved individuals who are not routinely tested because they are unaware of their exposure or risk status in order to increase testing among these populations and reduce Covid-19 related disparities.
Gender:
All
Ages:
Between 6 years and 120 years
Trial Updated:
12/03/2021
Locations: Contact Households, San Diego, California
Conditions: Covid19
A Mobile Health Intervention to Reduce Sweet Beverage Consumption in Latino Children
Recruiting
Sugar-sweetened beverage consumption is a major contributor to childhood obesity, caries, fatty liver disease, and Type 2 diabetes. Latino children are more likely to consume sugar-sweetened beverages (SSBs) and to suffer from all of the aforementioned conditions. Reading out loud to children from birth through age 5 is critical for the promotion of language and early literacy skills. Children whose parents read aloud to them are more likely to start school with the skills required for early rea... Read More
Gender:
All
Ages:
Between 12 months and 59 months
Trial Updated:
11/15/2021
Locations: San Francisco General Hospital Children's Health Center, San Francisco, California
Conditions: Child Obesity, Child Development
Osteopathic Manipulative Treatment for Recurrent Mastitis
Recruiting
This study will investigate whether Osteopathic Manipulative Treatment (OMT) is effective in treating recurrent mastitis without the use of antibiotics and if it helps in preventing future recurrence of mastitis in individuals who have had multiple occurrences of mastitis.
Gender:
Female
Ages:
Between 18 years and 50 years
Trial Updated:
11/12/2021
Locations: Western University of Health Sciences, Pomona, California
Conditions: Mastitis